RESUMO
Chlorella has a variety of biological activities, and it is worth further exploring its pharmacological effects. In this study, we investigated the antioxidant and anti-ageing activities of Chlorella polysaccharide extract (CPE). Further studies revealed that CPE exhibited anti-ageing, and antioxidant activities in vivo, including an extended Caenorhabditis elegans stress resistance, decreased deposition of lipofuscin, and reduced effects of amyloid ß protein on mobility, decreased levels of reactive oxygen species and increased activity of antioxidant enzymes. Moreover, it dramatically increased the expression of anti-stress and longevity genes and reduced the expression of ageing-related genes; therefore, it was hypothesised that the mechanism of the age-delaying effect of CPE was related to the insulin signalling pathway. In summary, CPE could delay ageing and provide a new avenue for the application and development of CPE.
RESUMO
The electrophysiological function of the tongue involves complicated activities in taste sense, producing the perceptions of salty, sweet, bitter, and sour. However, therapies and prevention of taste loss arising from dysfunction in electrophysiological activity require further fundamental research. Optogenetics has revolutionized neuroscience and brought the study of sensory system to a higher level in taste. The year 2022 marks a decade of developments of optogenetics in taste since this technology was adopted from neuroscience and applied to the taste research. This review summarizes a decade of advances that define near-term translation with optogenetic tools, and newly-discovered mechanisms with the applications of these tools. The main limitations and opportunities for optogenetics in taste research are also discussed.
RESUMO
NASICON type KTi2(PO4)3 decorated by NTCDA-derived carbon layer (KTP/NC) was prepared as anode material to obtain sustainable lithium/sodium ion storage (LIBs/SIBs). Due to its prominent capacitance, good electronic conductivity and ability to constrain volume, the KTP/NC composite realizes highly electrochemical kinetics both in LIBs and SIBs. For LIBs, the KTP/NC composite delivers a superior reversible capacity of 598.1 mAh g-1 after 200 cycles at 0.5C, impressive cyclability with 225.5 mAh g-1 after 3000 cycles at an ultrahigh current density of 26.1 C and conspicuous rate performance of 160.6 mAh g-1 even at 52.2 C. In addition, the composite has a wide operation-temperature window with favorable capacities of 147.1-372.9 mAh g-1 from -10 °C to 50 °C. As for SIBs, the KTP/NC composite maintains a stable discharge capacity of 112.5 mAh g-1 after 700 cycles at a current density of 2.6 C and conspicuous rate performance of 86.7 mAh g-1 at 5.2 C. The KTP/NC anode exhibits discharge capacities of 29.9-112.6 mAh g-1 from -10 °C to 40 °C. The results demonstrate that the KTP/NC composite would be a promising electrode material for LIBs and SIBs.
RESUMO
Hetero-MoO3/MoO2@N-doped carbon nanobelt anodes (h-MoO3/MoO2@NC) with long lifespan and superior rate capability were proposed by a simple in situ reduction tactic, in which pristine MoO3 was transformed into heterogeneous MoO3/MoO2. The hetero-MoO3/MoO2 architecture significantly improves the electronic conductivity and affords abundant oxygen deficiencies. Meanwhile, the synergistic effect of internal MoO3/MoO2 heterostructure and outer N-doped carbon layer (NC) accomplishes a balance of sustainable potassium/sodium storage and ultra-durable structure stability. In potassium ion batteries, the anodes steadily maintain a reversible capacity of 283 mAh g-1 after 6000 cycles at 0.5 A g-1 and 153 mAh g-1 after 1000 cycles under 2 A g-1, as well as an impressive rate capability of 131 mAh g-1 at 3 A g-1. In sodium ion batteries, the anodes purchase a steady capacity of 152 mAh g-1 even after 10,000 cycles at 2 A g-1, and 190 mAh g-1 after 5000 cycles at 0.5 A g-1. Moreover, the h-MoO3/MoO2@NC composite possesses a prominent pseudocapacitive effect and good thermal adaptability (-10 to 50 °C) in both KIBs and SIBs. The results indicate that the h-MoO3/MoO2@NC composite would be an auspicious material for potassium/sodium storage and other ion batteries.
