RESUMO
OBJECTIVE: Ossicular chain damage from chronic ear disease is a significant problem in the Australian population. The ideal ossicular chain reconstruction prosthesis has yet to be defined. This paper examines, for the first time, the use of a titanium prosthesis for ossicular chain reconstruction in Australian patients. STUDY DESIGN: Retrospective chart review. SUBJECTS AND METHODS: All patients undergoing ossicular chain reconstruction with a titanium prosthesis between 1 February 2002 and 31 March 2007. RESULTS: Results showed a low complication rate, with only one extrusion out of 55 cases (1.8 per cent). Successful rehabilitation of conductive hearing loss (i.e. to < or =20 dB air-bone gap) was obtained in 85 per cent of the partial ossicular chain reconstruction group and 77 per cent of the total ossicular chain reconstruction group. Pure tone thresholds improved by an average 18 dB in the partial reconstruction group and 25 dB in the total reconstruction group. CONCLUSION: Titanium is an ideal material for ossicular chain reconstruction due to its ease of insertion, low rate of extrusion and good functional results.
Assuntos
Ossículos da Orelha/cirurgia , Perda Auditiva Condutiva/cirurgia , Prótese Ossicular , Substituição Ossicular/métodos , Titânio/uso terapêutico , Adolescente , Adulto , Idoso , Austrália , Criança , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Recuperação de Função Fisiológica , Estudos Retrospectivos , Resultado do Tratamento , Adulto JovemRESUMO
Multiple myeloma remains a challenge for the treating physician, with extremely low complete response rates (5-10%) to conventional induction therapy. High dose therapy with autologous hematopoietic stem cell transplant results in improved response, event-free and overall survival and should be considered the standard of care for patients who are candidates for transplantation. Several newer treatment option are now available.
Assuntos
Mieloma Múltiplo/terapia , Humanos , Mieloma Múltiplo/complicações , Mieloma Múltiplo/patologia , Estadiamento de Neoplasias , PrognósticoRESUMO
Classical Freyer's method was modified in which, prostatic fossa was packed after the enucleation of the gland for hemostatic purpose; and the pack and suprapubic drain were brought out laterally. The pack was removed after 48-72 hours postoperatively and catheter was introduced per urethrum for early closure of suprapubic ostomy. Fifty such cases of Modified Freyer's prostatectomy were compared with cases of classical Freyer's prostatectomy (n = 25) and Millin's prostatectomy (n = 25). The duration of surgery and requirements for perioperative blood transfusion were found to be less with our method.
