1.
Org Biomol Chem
; 19(10): 2277-2283, 2021 03 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33624664
RESUMO
A three-component [3 + 2 + 1] annulation strategy for the synthesis of biologically and pharmaceutically active 2,3-diarylpyridine derivatives by using a series of allylic alcohols, ketones, and ammonium acetate as substrates has been developed. The method proceeds efficiently under metal-free conditions, and the desired heterocycles could be obtained in a site-specific selectivity manner with good functional group tolerance.