[Potential of the image analyzer "videotest" for performing microphotometric study in cytology]. / Vozmozhnosti analizatora izobrazhenii "videotest" dlia provedeniia mikrofotometricheskikh issledovanii v tsitologii.

Precision features of image analyser "Videotest" and possibilities of its applications for cytophotometric investigations have been analysed. It has been shown that a photometric feature is linear at least to optical density 1.1. Cytophotometry of the Feulgen stained rat hepatocyte nuclei has been performed. Coefficients of variation of DNA for 2c, 4c and 8c nuclei are 7.72, 7.65 and 6.50%, respectively, and ratios between average values of these nuclei are 1.00:2.06:4.12. Possible causes of errors of digital television equipment for cytophotometry are discussed.

Testing the safety and effectiveness of oral administration of a live influenza vaccine.

Tests to determine the reactogenicity and immunogenicity of a live influenza vaccine when administered by mouth showed that the new method caused no reactions in adults and children and was adequately immunogenic, the results being in no way inferior to those obtained by intranasal administration. These results provide a basis for the wider use of this simpler and more convenient method of administration.Oral administration of the live influenza vaccine was followed by reproduction of the vaccine virus. The rapid elimination of catarrhal symptoms existing before vaccination indicates intensive production of interferon in the nasopharynx of the vaccinated persons.The standard influenza vaccine for adults induced strong reactions in children, even when the less dangerous oral route of vaccination was used. For oral vaccination of children it is thus essential to use the variant of the live influenza vaccine made from further-attenuated, cold-adapted vaccine strains of influenza virus. This vaccine is quite safe and effective whether administered intranasally or by mouth.