Impacto del tratamiento alergológico integral en la calidad de vida de los pacientes con asma / Wholemeal allergologic treatment impact in the quality of life of patients with asthma

Introducción: Calidad de vida es la percepción del paciente de los efectos de suenfermedad y sus consecuencias terapéuticas. Con los cuestionarios validados yestandarizados se evalúa la calidad de vida de los pacientes con asma.Objetivo: Estimar el impacto del tratamiento alergológico integral en los pacientescon asma que acudieron a consulta al servicio de Alergia e InmunologíaClínica del Hospital Universitario de Puebla.Material y métodos: Se realizó un estudio prospectivo en pacientes con asmaalérgica de ambos sexos y mayores de 18 años, con inclusión de dos meses yseguimiento de 12 visitas. A cada paciente se le realizó la anamnesis, las pruebascutáneas, la espirometría y un cuestionario de calidad de vida y estimaciónde la gravedad al inicio y final del seguimiento. El tratamiento alergológico integralse basó en los criterios de GINA. El tamaño de la muestra se calculó deacuerdo a métodos estandarizados.Resultados: Se incluyeron 20 pacientes y todos terminaron el seguimiento. El85% era mujer y la edad media era de 41,8 años con una desviación estándarde 13,4. La gravedad más frecuente fue la moderada persistente en el 40% alinicio y al final del seguimiento y la intermitente en el 75%. Se observaron diferenciassignificativas entre el índice de calidad de vida al ingreso de los pacientesy durante el seguimiento a partir de la octava visita.Conclusión: El tratamiento alergológico integral modifica la calidad de vida yla gravedad de los pacientes con asma alérgica

Introduction: The quality of life is conceived as the perception of the patient of the functional effects of his/her illness and its therapeutics consequences. Development of validated and standardized questionnaires had may to evaluated the quality of life of patients with asthma. Objective: Determine the impact of integral alergologic treatment on quality of life of patients with allergic asthma visited in the external consultation of the service of Allergy and Clinical Immunology of the Hospital Universitario de Puebla. Material and methods: A prospective study was carried out in patients of both sexes, older than 18 years, whit allergic asthma, through a period of inclusion of two months with twelve visits of follow-up. History, skin test, spirometry and a standarized questionary were obtained in each patient, as well as estimation of severity degree of the illness at the beginning and at the end of the study. The integral allergic treatment was based on the Global Innitiative for Asthma judgments. The size of the sample was calculated according to standardized methods. Results: Twenty patients were included an all of them completed the follow-up. Eighty-five per cent of them were women. The average age was 41.8 years old with a SD of 13.4. The severity degree most frequent were the moderate persistent, with a 40% at inclusion and end of the follow- up, and the intermittent with a 75%. Significative differences between index of quality of life at the inclusion and during the follow-up were observed after 8th visit. Conclusion: The integral treatment modifies the quality of life and severity degree of the patients with allergic asthma

[Correlation between Blatella germanica and Periplaneta americana in allergic patients]. / Correlación entre Blatella germanica y Periplaneta americana en pacientes alérgicos.

BACKGROUND: It has been identified shared allergens from whole body between Blatella germanica and Periplaneta americana. It has been reported high correlation between both cockroaches. OBJECTIVE: To estimate correlation between skin test for two major species of intradomiciliary cockroaches. METHODS: It was included patients with clinical diagnostic of allergy pathology whom attended to external consult of Allergy and Clinical Immunology Service of the Hospital Universitario de Puebla in a period of six months, prick skin tests with standardized antigens of Blatella germanica and Periplaneta americana were made. RESULTS: One hundred twenty patients were enrolled in the study, 54.2% were women and 45.8% were men, with a mean age of 15.7 years old. The correlation coefficient between Germany cockroach and American cockroach to erythema was 0.49 and to papule was 0.40. CONCLUSION: The outcomes showed a moderate correlation or a considerable relation between both cockroaches whether erythema or papule. Based on the results presented, we suggest to evaluate both antigens in order to improve diagnostic accuracy.

[Incidence of adverse reactions to immunotherapy in allergic patients at Puebla University Hospital]. / Incidencia de reacciones adversas a la inmunoterapia en pacientes alérgicos del Hospital Universitario de Puebla.

MATERIAL AND METHOD: In order to know adverse reaction incidence to, immunotherapy, it realized a longitudinal, prospective and descriptive study in patients of outward consultation of Allergy Immunology Clinic Service of Hospital Universitario de Puebla in a period of 10 months. It determined age, sex, diagnostic, reaction adverse kind and presentation time of them. Initial immunotherapy dose was 0.05 ml administered subcutaneously with treatment antigens 1:100 weight/volume without premedication. It included 170 patients with average age of 22.6 years (SID 15.4), 56.5% female sex and 43.5% male. RESULTS: Most frequent pathologics were asthma and rhinitis. Adverse reactions incidence at specific immunotherapy were 2.4%, all of them were of immediate and local kind. CONCLUSION: These results are influence by the concentration and dose of antigens utilized and may differ of another studies.

[Validity of a scale of vital prognosis in multiorgan failure syndrome: experience at a pediatric ICU]. / Validez de una escala de pronóstico vital en el síndrome de falla multiorgánica: experiencia de una UCI pediátrica.

In order to evaluate the utility of modified score index for multiple organ failure syndrome (MOFS) detection, we studied 31 critically ill pediatric patients at University Hospital of Puebla. They had a critical illness and they were successfully animated and developed two or more organ failure other than initial lesion. Were calculated sensibility, specificity, positive predictive value and negative predictive value of clinical and biochemical criterion of modified score index and results were few consistent. Were assessed that scale for know its predictive value and results were significant: sensitivity 81%, specificity 30% and accuracy, 54.5%. Finally we recommended caution to use anyone score system in evaluating MOFS.