Correction: An examination of the prospective association between physical activity and academic achievement in youth at the population level.

[This corrects the article DOI: 10.1371/journal.pone.0253142.].

Medial prefrontal brain activity correlates with emerging symptoms of anxiety and depression in late adolescence: A fNIRS study.

The brain undergoes dramatic changes over the course of the adolescent years, and these developmental changes are implicated in the emergence of disorders that involve negative emotionality. Late adolescence might be the window within which brain networks manifest vulnerabilities to depressive and anxiety symptomology; particularly within the prefrontal cortex (PFC), which houses emotional control (dorsolateral) and emotional processing (medial) nodes. Given the comorbidity of depressive and anxious symptomology, it may be that the neural signature is similar for both within the developing PFC. In a sample of 67 adolescents (M = 15.97 years, SD = 1.36), we used functional near-infrared spectroscopy (fNIRS) to examine the neural signature of emergent anxiety and depressive symptoms among younger and older adolescents. We further examined the extent to which neural signatures of anxiety and depressive symptoms within the PFC were similar or different. Findings revealed that self-reported anxiety and depressive symptoms were highly correlated, and that the neural signatures of both within the PFC were similar, corresponding with the medial subregions of the PFC (i.e., those involved in evaluative processing). These findings were evident only in later adolescence, suggesting the possibility of a common vulnerability for anxiety and depressive disorders emerging around this developmental window.

Examining the relationships among adolescent health behaviours, prefrontal function, and academic achievement using fNIRS.

Several adolescent health behaviours have been hypothesized to improve academic performance via their beneficial impact on cognitive control and functional aspects of the prefrontal cortex (PFC). The primary objective of this study is to examine the association between lifestyle behaviours and academic performance in a sample of adolescents, and to examine the extent to which activity within the PFC and behavioural indices of inhibition may mediate this relationship. Sixty-seven adolescents underwent two study sessions five days apart. Sleep and physical activity were measured using wrist-mounted accelerometry; eating habits, substance use and academic achievement were measured by self-report. Prefrontal function was quantified by Multi-Source Interference Task (MSIT) performance, and task-related activity via functional near-infrared spectroscopy (fNIRS). Higher levels of physical activity predicted higher MSIT accuracy scores (ß = .321, ρ = 0.019) as well as greater activation within the right dlPFC (b = .008, SE = .004, ρ = .0322). Frequency of fast-food consumption and substance use were negatively associated with MSIT accuracy scores (ß = -0.307, ρ = .023) and Math grades (b = -3.702, SE = 1.563, ρ = .022), respectively. Overall, the results of this study highlight the importance of lifestyle behaviours as predictors of prefrontal function and academic achievement in youth.

An examination of the prospective association between physical activity and academic achievement in youth at the population level.

Exercise has significant benefits for brain health and this may have downstream learning benefits for youth. However existing studies looking at links between physical activity and academic achievement are limited by relatively small sample sizes and/or cross-sectional designs. The objective of this study is to determine the direction and magnitude of the association between physical activity and academic achievement in a large prospective sample of adolescents. Linear mixed models with random intercepts and multinomial ordinal generalized estimating equations were employed to analyze the prospective relationship between measures of physical activity and academic achievement from the COMPASS study (N = 9,898 linked participant data cases from year 2 (2013-2014) to year 4 (2015-2016)). The linear relationships between minutes of moderate to vigorous physical activity and academic achievement (English: r = -.047, p < .000; Math: r = -.026, p = .008) as well as meeting the national physical activity guidelines and academic achievement (English: est = -.052, p = .004; Math: est = -.052, p = .028) were negative and trivial in magnitude. Organized sport participation showed slight positive associations with academic achievement indices, but these were also of trivial magnitude. In conclusion, the relationship between physical activity and academic achievement was effectively null in this population sample. Advocacy for physical activity programming for adolescent populations may best be undertaken with reference to lack of net academic achievement cost, rather than presence of benefit, or simply with reference to the many other physical and mental health benefits for youth.