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1.
Appl Opt ; 48(4): B73-9, 2009 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-19183584

RESUMO

Cavity-enhanced tunable diode laser absorption spectroscopy is an attractive method for measuring small concentrations of gaseous species. Ethane is a breath biomarker of lipid peroxidation initiated by reactive oxygen species. A noninvasive means of quickly quantifying oxidative stress status has the potential for broad clinical application. We present a simple, compact system using off-axis integrated cavity output spectroscopy with an interband cascade laser and demonstrate its use in real-time measurements of breath ethane. We demonstrate a detection sensitivity of 0.48 ppb/Hz(1/2).


Assuntos
Testes Respiratórios/instrumentação , Testes Respiratórios/métodos , Etano/análise , Lasers , Espectrofotometria Infravermelho/instrumentação , Desenho de Equipamento , Análise de Falha de Equipamento , Humanos , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Espectrofotometria Infravermelho/métodos , Integração de Sistemas
2.
Appl Opt ; 46(27): 6759-69, 2007 Sep 20.
Artigo em Inglês | MEDLINE | ID: mdl-17882296

RESUMO

We have used aperiodically poled lithium niobate waveguides to perform intensity autocorrelation and frequency-resolved optical gating (FROG) measurements for ultraweak femtosecond pulses at 1.5 microm wavelength. The required pulse energies for intensity autocorrelation and FROG are as low as 52 aJ and 124 aJ, respectively. The corresponding sensitivities are 3.2 x 10(-7) mW(2) and 2.7 x 10(-6) mW(2), about 3-5 orders of magnitude better than the previous records. The high nonlinear conversion efficiency is attributed to the long waveguide structure, and the needed broad phase-matching bandwidth is realized by chirping the poling period. We discuss the theory of intensity autocorrelation and FROG measurements in the presence of different phase-matching bandwidths, and we show, for the first time to our knowledge, that the distorted intensity autocorrelation trace due to a delta-like phase-matching spectrum is described by a modified field autocorrelation function. We also report new experimental results comparing autocorrelation traces measured with chirped and unchirped waveguide samples and demonstrating high-quality FROG measurements for cubic phase waveforms generated in a programmable pulse shaper.

3.
Opt Express ; 14(22): 10255-60, 2006 Oct 30.
Artigo em Inglês | MEDLINE | ID: mdl-19529422

RESUMO

We demonstrate an all-optical half adder for bit-wise addition of two serial data streams that simultaneously generates Sum and Carry outputs. The module performs the required XOR and AND operations using only two nonlinear optical elements. Difference Frequency Generation in a periodically poled lithium niobate waveguide serves as the AND gate and cross-gain modulation in a semiconductor optical amplifier is employed to generate the XOR output. Error free operation for RZ data is reported.

4.
Opt Lett ; 30(16): 2164-6, 2005 Aug 15.
Artigo em Inglês | MEDLINE | ID: mdl-16127944

RESUMO

We retrieve intensity and phase profiles of 280 fs, 50 MHz optical pulses with 124 aJ coupled pulse energy (960 photons) by second-harmonic generation (SHG) frequency-resolved optical gating, using aperiodically poled LiNbO3 waveguides. The strong nonlinear interaction that is due to confinement within the micrometer-sized waveguide structure and the linearly chirped poling period contribute, respectively, to high SHG efficiency and broad phase-matching bandwidth. The achieved sensitivity is 2.7 x 10(-6) mW2, improving on the previous record for self-referenced complete pulse characterization by 5 orders of magnitude.

5.
Opt Lett ; 29(17): 2070-2, 2004 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-15455783

RESUMO

We demonstrate ultrasensitive intensity autocorrelation measurements of subpicosecond optical pulses in the telecommunication band by using aperiodically poled lithium niobate (A-PPLN) waveguides. The tightly confined optical beam in the waveguides and the chirped poling period facilitate simultaneous high second-harmonic generation (SHG) efficiency and broad phase-matching (PM) bandwidth. The resulting measurement sensitivity is 3.2 x 10(-7) mW2, approximately 500 times better than the previous record for intensity autocorrelations. We also show that chirped A-PPLN waveguides retain nearly the same SHG efficiency as the unchirped guide as long as the PM bandwidth is not significantly broader than the input spectrum.

6.
Opt Lett ; 27(1): 43-5, 2002 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-18007710

RESUMO

We report 99% pump depletion in single-pass second-harmonic generation. Quasi-cw pulses at 1550 nm were frequency doubled in an annealed proton-exchanged waveguide formed in periodically poled lithium niobate. Measurements of pump depletion and second-harmonic generation agree with results from numerical integration of the coupled-mode equations that describe the process.

7.
Opt Lett ; 27(3): 179-81, 2002 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-18007748

RESUMO

Efficient three-wave mixing devices have numerous applications, including wavelength conversion, dispersion compensation, and all-optical switching. Second-harmonic generation (SHG) is a useful diagnostic for near-degenerate operation of these devices. With buried waveguides formed in periodically poled lithium niobate by annealed and reverse proton exchange, we demonstrate what is believed to be the highest normalized conversion efficiency (150%/W cm(2)) for SHG in the 1550-nm communications band reported to date.

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