Nutritional Risk, Depression, and Physical Function in Older People Living Alone.

This study investigated depression and physical function as factors associated with nutritional risk in older adults living alone. The study included 2896 people 65 years or older who lived alone. Data were collected in South Korea between September and November 2020. Descriptive statistics, a chi-squared test, independent samples t-test, weighted multiple regression analysis, and binary logistic regression analysis were performed using IBM SPSS for Windows ver. 23.0. In this study, 44.8% of participants were in the nutritional risk group. Furthermore, 60.9% of those at risk for depression, 75.1% of those with instrumental activities of daily living (IADLs) dependency, and 59.1% of those with chewing limitations were at nutritional risk. The factors that increased nutritional risk in the weighted multiple regression analysis were depression (ß = 0.27, p < 0.001), chewing limitations (ß = 0.12, p < 0.001), IADL dependency (ß = 0.09, p < 0.001), and basic physical movement (ß = 0.04, p = 0.020). Binary logistic regression analysis showed that those with IADL dependency had a 2.59 times higher nutritional risk than those with IADL non-dependency (p < 0.001). The nutritional risk group had a higher risk of depression (2.01 times higher [p < 0.001]), chewing limitations (1.76 times higher [p < 0.001]), and basic physical movement limitations (1.35 times higher [p = 0.009]) than the good nutritional group. Therefore, nutritional screening is required of older individuals living alone. To mitigate nutritional risks, it is necessary to assess depression and physical function, including IADL dependency.

Social Interaction and Life Satisfaction among Older Adults by Age Group.

This study examined the effect of social interaction on life satisfaction in older adults. A total of 8188 participants were selected according to the inclusion criteria. SPSS Windows software (version 23.0) was used for statistical analyses. Data were analyzed using the independent samples t-test, chi-squared test, and multiple regression analysis with weights based on two age groups: 65-74 and ≥75 years. The results showed that social interaction factors influenced the life satisfaction of older adults. In the 65-74 age group, factors that statistically significantly increased life satisfaction were meeting children (ß = 0.17, p < 0.001) and volunteer activities (ß = 0.04, p = 0.007). In the ≥75 age group, factors that significantly increased life satisfaction were talking with friends (ß = 0.11, p = 0.002), talking with children (ß = 0.07, p = 0.013), using senior citizen community centers (ß = 0.08, p = 0.001), and hobby club activities (ß = 0.07, p = 0.001). In order to increase the life satisfaction of older adults, different ways to support social interactions need to be explored.

The Effects of Manual Acupuncture on Mitochondrial Fusion and Fission Gene Expression in Rat Spleen.

Background: A significant amount of research has been conducted to establish the validity of acupuncture, and it has been demonstrated through animal disease model studies that acupuncture influences mitochondrial changes. However, to more accurately examine the mechanisms of acupuncture treatment effectiveness in pathological models, it is crucial to investigate changes in disease-free animals. Among various hypotheses regarding the effects of acupuncture on the body, we focused on the result that acupuncture stimulation is related to mitochondria. Objectives: We examined the effects of acupuncture mitochondrial fission and fusionrelated mediators in disease-free Sprague Dawley (SD) rats' spleen meridian acupoints. Methods: SD rats were divided into control, SP1, SP2, SP3, SP5, and SP9 acupuncture groups. Acupuncture was performed at each point for 10 minutes daily for four days. Peroxisome proliferator-activated receptor-gamma coactivator 1-α (PGC-1α) and fission protein 1 (Fis1) levels were evaluated using quantitative real-time polymerase chain reaction (qRT-PCR), while dynamin-related protein 1 (DRP1), optic atrophy-1 (OPA1), mitofusin-1 (MFN1), and mitofusin-2 (MFN2) levels were assessed via western blotting. Mitochondria protein concentrations and NADH dehydrogenase activity in spleen tissues were measured using enzyme-linked immunosorbent assay (ELISA). Results: PGC-1α expression decreased in the SP1 (p < 0.01), SP5 (p < 0.05), and SP9 (p < 0.05) groups, while Fis1 expression increased in the SP1 (p < 0.01), SP5 (p < 0.01), and SP9 (p < 0.05) groups. DRP1, OPA1, MFN1, and MFN2 levels exhibited no significant changes. Mitochondrial protein concentrations decreased in the SP2 (p < 0.01), SP3 (p < 0.01), SP5 (p < 0.01), and SP9 (p < 0.01) groups, while NADH dehydrogenase activity decreased in the SP2 (p < 0.05) and SP9 (p < 0.05) groups. Conclusion: Acupuncture at the SP9 acupoint influenced the mitochondrial fission pathway by modulating PGC-1α and Fis1 mediators in the rat spleen under non-disease conditions.

Factors Related to Life Satisfaction of Older Adults at Home: A Focus on Residential Conditions.

This study examined which residential conditions increase older adults' life satisfaction at home. We used data from 8903 participants over 65 years old who did not need help in their daily lives from a 2020 survey of older adults conducted by the Korea Institute for Health and Social Affairs. Data analysis was conducted using descriptive statistics, independent sample t-test, Pearson correlation analysis, and hierarchical multiple regression with weights. The final model explained 34.2% of life satisfaction in old age. Residential conditions that increased life satisfaction the most in old age were the community environment (ß = 0.16, p < 0.001) and satisfaction with the house (ß = 0.15, p < 0.001). Other conditions that significantly affected life satisfaction were safety (ß = 0.08, p < 0.001), interaction with neighbors (ß = 0.08, p < 0.001), distance from children or relatives (ß = 0.08, p < 0.001), frequency and route of public transportation (ß = 0.05, p < 0.001), and abundance and distance of green spaces (ß = 0.02, p = 0.031). Housing welfare policies should consider these results to increase life satisfaction for an increasingly aging population. Moreover, these data can be used to design age-friendly community environments.

College Life Adjustment, Life Stress, Career Barriers, and Career Decision-Making Self-Efficacy of College Students Who Have Experienced COVID-19 in South Korea.

University life is challenging for students, given the college life adjustment, life stress, career barriers, and career decision-making self-efficacy required. COVID-19 has made this even more complex. This study investigated the relationships among these factors in college students who experienced COVID-19. Data were collected using an online cross-sectional structured survey of 1242 university students from December 2020 to January 2021. Data were analyzed via independent-sample t-tests, one-way ANOVAs, Pearson's correlation coefficient, multiple regression, and logistic regression, using SPSS. College life adjustment was significantly correlated with life stress (r = −0.255, p < 0.001), career barriers (r = −0.429, p < 0.001), and career decision-making self-efficacy (r = 0.531, p < 0.001). The regression analysis showed that career barriers, career decision-making self-efficacy, and grade level had a total explanatory power of 33.7% for college life adaptation. The logistic regression analysis showed that the odds ratio (OR) of career barriers being low in the group with a high college life adaptation score was 2.045 (p < 0.001), and the OR of career decision-making self-efficacy being high was 4.107 (p < 0.001), as compared to the group with a low score. To increase college students' adaptation to college life, career support programs that improve career barriers and career decision-making self-efficacy should be developed.

Nursing Students' Acceptance Intention of a Smart Device, Information Literacy, and Problem-Solving Confidence.

The purpose of this study was to investigate the relationship between nursing students' acceptance intention of a smart device, information literacy, and problem-solving confidence to explore the factors that may improve nursing students' problem-solving confidence. Data were collected from 450 nursing students between July and August 2019 in two cities in Korea. The results showed that there is a positive correlation between problem-solving confidence and acceptance intention (r = 0.353, p < 0.001) and between problem-solving confidence and information literacy (r = 0.501, p < 0.001). Further, participants with high acceptance intention of a smart device and information literacy scores had significantly higher problem-solving confidence (t = 5.447, p < 0.001; t = 10.072, p < 0.001) than participants with low acceptance intention. In addition, in the logistic regression the odds ratio between the acceptance intention of a smart device, information literacy, and problem-solving confidence groups was odds ratio 2.071 (p < 0.001, CI: 1.412-3.037) and odd ratio 4.966 (p < 0.001, CI: 3.298-7.477). To improve nursing students' problem-solving confidence, educational strategies should be developed to build information experience and information utilization capabilities.

Test-Retest Reliability of Word Recognition Score Using Korean Standard Monosyllabic Word Lists for Adults as a Function of the Number of Test Words.

BACKGROUND AND OBJECTIVES: The purpose was to establish the test-retest reliability of word recognition score (WRS) using Korean standard monosyllabic word lists for adults (KS-MWL-A) recently developed based on the international standard for speech audiometry (ISO 8253-3:2012). SUBJECTS AND METHODS: Subjects consisted of 159 adults aged to 18 to 25 years with normal hearing sensitivity. WRSs were obtained in 2 dB steps from the level of speech recognition thresholds to the level of 86% correct responses or greater. After one or two weeks, retest was performed. Correlation, confidence interval (CI) and prediction interval (PI) were calculated for the reliability. RESULTS: Correlation coefficients were 0.88 for 50 test words, 0.76 for 25 and 0.61 for 10 words. Results also showed that 95% CIs and PIs were narrower for 25 and 50 test words than those for 10 test words. CONCLUSIONS: Korean WRS using the KS-MWL-A has high reliability for 25 and 50 test words, but relatively low for 10 words. It suggested that 95% CIs for each test words would be criteria for significant differences in WRS for groups and 95% PIs at each score of WRS could be utilized for a considerable difference for each individual at retest.

The effects of auditory short-term training in passive oddball paradigm with novel stimuli.

BACKGROUND AND OBJECTIVES: The purpose of this study was to determine how human neural activity might be changed through auditory short-term training when listening to novel stimuli. SUBJECTS AND METHODS: Among the twenty young normal hearing adult listeners who participated, ten were randomly assigned to a training group and ten were assigned to a non-training group as a control. Two synthesized novel stimuli were used: /su/ and /∫u/. Both stimuli similarly sounded like /su/, but had two different onset transition frequencies and fricative pole frequencies. In the experiment, behavioral identification test (i.e., /su/ vs. /∫u/) and the mismatch negativity (MMN) were measured before and after training for the training group. To gauge the training effect, the listeners in the training group were taught by discrimination and identification of two novel stimuli for about 20 minutes. RESULTS: The results showed that scores for the behavioral test increased significantly after auditory short-term training. Also, onset latency, duration, and area of the MMN were significantly changed when elicited by the training stimuli. CONCLUSIONS: These findings indicated that auditory short-term training could change human neural activity, suggesting future clinical applications for auditory training.