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Biochem Soc Trans ; 44(3): 877-82, 2016 06 15.
Artigo em Inglês | MEDLINE | ID: mdl-27284055

RESUMO

Membrane proteins represent one of the most important targets for pharmaceutical companies. Unfortunately, technical limitations have long been a major hindrance in our understanding of the function and structure of such proteins. Recent years have seen the refinement of classical approaches and the emergence of new technologies that have resulted in a significant step forward in the field of membrane protein research. This review summarizes some of the current techniques used for studying membrane proteins, with overall advantages and drawbacks for each method.


Assuntos
Proteínas de Membrana/isolamento & purificação , Membranas Artificiais , Métodos , Bactérias/metabolismo , Eucariotos/metabolismo , Humanos , Proteínas de Membrana/metabolismo , Proteínas de Membrana/fisiologia
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