Pantokrator Monastery-Zeyrek Mosque: The Preserved Byzantine Hospital in Istanbul.

BACKGROUND: Istanbul, home to numerous historical treasures, houses one of the oldest fully constructed hospitals. METHODS: This 50-bed hospital was built in the early 12th century during the Byzantine period by Empress Irene of Hungary and her husband Emperor John II Komnenos inside one of the largest monasteries of its time. The monastery housed one of the first hospitals and schools of medicine and included a nursing home, ophthalmologic health center, library, and cemetery. After the Empress died, her husband continued to enlarge the complex to its current state. Soon after the fall of Constantinople in 1453, the complex was renamed after Zeyrek Mehmet, who was ordered by Fatih Sultan Mehmet (Mehmet II or Mehmed the Conqueror) to convert the monastery into a mosque, constructing a Fatih Medrese for a short period of time. The hospital, however, remained untouched, and its rooms were used for Koran lessons. The building was fully restored from 2009 to 2017 and is still used as a mosque today. We would like to introduce the Pantokrator Monastery, maybe the only remaining hospital of the Byzantine era. CONCLUSION: Although it was built in the 12th century, the monastery is still a modern facility meeting current standards.

Microneurosurgical Removal of a Cervical Intramedullary Tumor Via Hemilaminoplasty: 3-Dimensional Operative Video.

Intramedullary tumors of the spinal cord are rare and account for 2% to 8.5% of all central nervous system tumors. In adults, ependymomas are the most common intramedullary tumors. The primary choice of treatment should be radical surgical removal, as this is curative for most tumors. Adequate tumor exposure is crucial and mostly achieved through standard laminectomy followed by midline myelotomy. However, extensive removal of posterior spinal elements may lead to worsening kyphotic deformities. After obtaining patient consent, this 3-dimensional video publication was prepared to present microneurosurgical removal of a C3-C6 cervical intramedullary tumor using right-sided hemilaminoplasty. C3-C6 hemilaminae were lifted en bloc. After dural and arachnoid incision, midline myelotomy was performed. Using microneurosurgical technique, the tumor was removed totally. After the dural closure, C3-C6 hemilaminae were placed into the previous position and reconstructed with mini-plates and screws. Preserving contralateral paraspinal muscles, spinous processes, midline spinal ligaments and bilateral facet joints helped maintaining the alignment of the spinal column. Comparing to laminectomy, hemilaminoplasty, decreases the postoperative pain and the total blood loss as only one side muscle dissection is enough. In the presented case, postoperative MRI showed total removal of the tumor. The final histopathology report indicated an ependymoma (WHO-Grade 2). Successful bone healing was demonstrated by postoperative cervical radiographs and CT scans. The patient has no postoperative neurological deficit. In conclusion, hemilaminoplasty is an effective and a less-invasive method in removal of intradural-intramedullary tumors with its advantages such as preventing the instability and reduction of blood loss and postoperative pain.