Long-term surveillance of the feline leukemia virus in the endangered Iberian lynx (Lynx pardinus) in Andalusia, Spain (2008-2021).

Feline leukemia virus (FeLV) infection is considered one of the most serious disease threats for the endangered Iberian lynx (Lynx pardinus) Over 14 years (2008-2021), we investigated FeLV infection using point-of-care antigen test and quantitative real-time TaqMan qPCR for provirus detection in blood and tissues in lynxes from Andalusia (Southern Spain). A total of 776 samples from 586 individuals were included in this study. The overall prevalence for FeLV antigen in blood/serum samples was 1.4% (5/360) (95% CI: 0.2-2.6), FeLV proviral DNA prevalence in blood samples was 6.2% (31/503) (95% CI: 4.1-8.6), and FeLV proviral DNA in tissues samples was 10.2% (34/333) (95% CI: 7-13.5). From a subset of 129 longitudinally sampled individuals, 9.3% (12/129) PCR-converted during the study period. Our results suggest that FeLV infection in the Andalusian population is enzootic, with circulation of the virus at low levels in almost all the sampling years. Moreover, since only one viremic individual succumbed to the infection, this study suggests that lynxes may therefore control the infection decreasing the possibility of developing a more aggressive outcome. Although our results indicate that the FeLV infection in the Iberian lynx from Andalusia tends to stay within the regressive stage, continuous FeLV surveillance is paramount to predict potential outbreaks and ensure the survival of this population.

Correlación colpocitológica e histológica de la neoplasia cervical intraepitelial (NIC) en el ION-Solca

El cáncer cervico uterino es un problema de vital importancia para nosotros. Es el tipo de cáncer más frecuente en las mujeres ecuatrorianas. El 60 por ciento de todos los casos acuden en estadío clínico III y IV, y de éstos la sobrevida a cinco años es del 25 por ciento, con una sobrevida libre de enfermedad a 5 años del 10 por ciento. Los programas de detección temprana que comenzaron hace 20 años, han permitido diagnósticos más precoces y seguramente estamos mejorando nuestros resultados. Actualmente usamos para el diagnostico citológía, colposcopía, Biopsia dirigida y conización. Lamentablemente no contamos con otros auxilios diagnósticos como: tipificación del HPV, inmunoperoxidasa, microscopia de fluorescencia aplicada al cito diagnóstico, haciendo una correlación entre ellos.