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Clin Nucl Med ; 27(7): 494-8, 2002 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-12072776

RESUMO

An unexpected elevated postimplant radiation survey is described in an elderly patient with an interstitial low-dose-rate iridium-192 (Ir-192) needle implant for endometrial cancer. The elevated activity was related to prolonged clearance of Tl-201 from a cardiac study that had been performed 7 days earlier. The Tl-201 accumulated in the soft tissue, particularly the colon, resulting in increased survey readings over the abdomen and raising concern that an Ir-192 source remained within the patient. This case shows that delayed excretion of a diagnostic radionuclide agent can cause elevated activity high enough to confound postradiotherapy implant survey readings. The estimated surface exposure from a single iridium source left in the pelvis was determined using a phantom study. Possible factors causing decreased excretion of Tl-201 in a patient with heart disease, arteriosclerotic vascular disease, previous pelvic radiation therapy, and a brachytherapy procedure are discussed. A preloading radiation survey is recommended in patients who have had previous nuclear medicine studies involving radionuclides with long half-lives.


Assuntos
Abdome/diagnóstico por imagem , Adenocarcinoma/radioterapia , Neoplasias do Endométrio/radioterapia , Radioisótopos de Irídio/uso terapêutico , Tálio/farmacocinética , Contagem Corporal Total/métodos , Braquiterapia/efeitos adversos , Braquiterapia/métodos , Feminino , Humanos , Obstrução Intestinal/diagnóstico por imagem , Obstrução Intestinal/etiologia , Taxa de Depuração Metabólica/fisiologia , Pessoa de Meia-Idade , Modelos Biológicos , Miocárdio/metabolismo , Proteção Radiológica , Cintilografia
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