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Emerg Infect Dis ; 13(5): 719-25, 2007 May.
Artigo em Inglês | MEDLINE | ID: mdl-17553250

RESUMO

In April 2005, 4 transplant recipients became ill after receiving organs infected with lymphocytic choriomeningitis virus (LCMV); 3 subsequently died. All organs came from a donor who had been exposed to a hamster infected with LCMV. The hamster was traced back through a Rhode Island pet store to a distribution center in Ohio, and more LCMV-infected hamsters were discovered in both. Rodents from the Ohio facility and its parent facility in Arkansas were tested for the same LCMV strain as the 1 involved in the transplant-associated deaths. Phylogenetic analysis of virus sequences linked the rodents from the Ohio facility to the Rhode Island pet store, the index hamster, and the transplant recipients. This report details the animal traceback and the supporting laboratory investigations.


Assuntos
Animais Domésticos/virologia , Busca de Comunicante , Hospedeiro Imunocomprometido , Coriomeningite Linfocítica/transmissão , Vírus da Coriomeningite Linfocítica , Roedores/virologia , Animais , Cobaias , Humanos , Vírus da Coriomeningite Linfocítica/classificação , Vírus da Coriomeningite Linfocítica/genética , Camundongos , Filogenia , Ratos , Transplantes/efeitos adversos , Estados Unidos/epidemiologia , Zoonoses/transmissão , Zoonoses/virologia
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