1.
Org Biomol Chem
; 17(12): 3258-3266, 2019 03 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30847455
RESUMO
An additive/Brønsted acid/base free, highly efficient and chemoselective transetherification of electron deficient vinylogous esters and water mediated de-alkylation using an earth-abundant Fe-catalyst under very mild reaction conditions is described. This reaction is highly selective to primary alcohols over secondary alcohols, has good functional group tolerance, is scalable to gram scale and a purification free sequential transetherification in a continuous flow mode is demonstrated.