RESUMO
The heart rate variability estimation was used for autonomous regulation diagnostic in the 7-day head down bedrest experiment (HDBR). The new device "Pneumocard" and the fix respirations test were applied. The growth of sympathetic activity of autonomous nervous system and reduction of functional reserves of regulation mechanisms were observed in the microgravity modeling by HDBR. The analysis of the individual data had shown, that at two volunteers with most significant growth of SI after the experiment the orthostatic intolerance was observed. The data received in experiment confirm a hypothesis that growth of sympathetic activity in microgravity is accompanied by reduction of regulation mechanisms functional reserves is prognostic unfavorable.