RESUMO
PURPOSE: To compare polyglactin 910 and simple catgut sutures for the incidence of intraperitoneal adhesions. METHODS: Twenty female Wistar rats were placed into two groups. Group 1 received ischemic sutures and Group 2 received polyglactin 910. Five sutures inductive of adhesions in each rat were made. After 14 days, the rats were euthanized with an assessment of the presence of adhesions, the number of sutures involved and classification according to the Granat et al. scale described by Ozel et al17. RESULTS: In total, 19 of the 20 rats presented adhesions, with nine from Group 1 and ten from Group 2. There was a smaller number of affected sutures in Group 1, while in Group 2 the majority of the sutures formed adhesions (p=0.0197). According to the Granat et al. scale, Group 1 predominately developed fine, filamentous adhesions or thickening in a restricted area. Group 2 mainly presented extensive, thick adhesions with the involvement of the viscera (p=0.0055). CONCLUSION: Polyglactin 910 sutures formed more adhesions that were more extensive and thicker than the simple catgut sutures.
Assuntos
Categute/efeitos adversos , Isquemia/etiologia , Doenças Peritoneais/etiologia , Peritônio/cirurgia , Poliglactina 910/efeitos adversos , Técnicas de Sutura/efeitos adversos , Animais , Categute/normas , Modelos Animais de Doenças , Feminino , Doenças Peritoneais/prevenção & controle , Peritônio/irrigação sanguínea , Poliglactina 910/farmacocinética , Complicações Pós-Operatórias/etiologia , Ratos , Ratos Wistar , Aderências Teciduais/etiologia , Aderências Teciduais/prevenção & controleRESUMO
Abstract Purpose: To compare polyglactin 910 and simple catgut sutures for the incidence of intraperitoneal adhesions. Methods: Twenty female Wistar rats were placed into two groups. Group 1 received ischemic sutures and Group 2 received polyglactin 910. Five sutures inductive of adhesions in each rat were made. After 14 days, the rats were euthanized with an assessment of the presence of adhesions, the number of sutures involved and classification according to the Granat et al. scale described by Ozel et al17. Results: In total, 19 of the 20 rats presented adhesions, with nine from Group 1 and ten from Group 2. There was a smaller number of affected sutures in Group 1, while in Group 2 the majority of the sutures formed adhesions (p=0.0197). According to the Granat et al. scale, Group 1 predominately developed fine, filamentous adhesions or thickening in a restricted area. Group 2 mainly presented extensive, thick adhesions with the involvement of the viscera (p=0.0055). Conclusion: Polyglactin 910 sutures formed more adhesions that were more extensive and thicker than the simple catgut sutures.
Assuntos
Animais , Feminino , Ratos , Doenças Peritoneais/etiologia , Peritônio/cirurgia , Poliglactina 910/efeitos adversos , Técnicas de Sutura/efeitos adversos , Categute/efeitos adversos , Isquemia/etiologia , Doenças Peritoneais/prevenção & controle , Peritônio/irrigação sanguínea , Poliglactina 910/farmacocinética , Complicações Pós-Operatórias/etiologia , Aderências Teciduais/etiologia , Aderências Teciduais/prevenção & controle , Categute/tendências , Ratos Wistar , Modelos Animais de DoençasRESUMO
Purpose: To compare polyglactin 910 and simple catgut sutures for the incidence of intraperitoneal adhesions. Methods: Twenty female Wistar rats were placed into two groups. Group 1 received ischemic sutures and Group 2 received polyglactin 910. Five sutures inductive of adhesions in each rat were made. After 14 days, the rats were euthanized with an assessment of the presence of adhesions, the number of sutures involved and classification according to the Granat et al. scale described by Ozel et al17.Results: In total, 19 of the 20 rats presented adhesions, with nine from Group 1 and ten from Group 2. There was a smaller number of affected sutures in Group 1, while in Group 2 the majority of the sutures formed adhesions (p=0.0197). According to the Granat et al. scale, Group 1 predominately developed fine, filamentous adhesions or thickening in a restricted area. Group 2 mainly presented extensive, thick adhesions with the involvement of the viscera (p=0.0055).Conclusion: Polyglactin 910 sutures formed more adhesions that were more extensive and thicker than the simple catgut sutures.(AU)