[Our experience with the treatment of high perianal fistulas with the mucosal flap advancement technique]. / Trattamento delle fistole perianali alte con la tecnica del lembo mucoso di avanzamento.

The authors present their experience with the treatment of high transphincteric anal fistulas with the mucosal flap advancement technique. This technique, though by no means easy to perform, allows fistulas to be treated in a single surgical session in comparison to the technique in which setone is used or to the less well known transposition techniques, given the same long-term results in terms of continence and recurrence rate. After a brief overview of the problem, from the points of view of both aetiopathogenesis and classification, the principal surgical treatment techniques are described, presenting the results and complications observed in the authors' own case series.

[Antibiotic prophylaxis in laparoscopic cholecystectomy: from empiricism to evidence. Review of the problem and proposal of a randomized trial of the Lap Group Roma]. / Antibioticoprofilassi in corso di colecistectomia laparoscopica: dall'empirismo all'evidenza. Revisione del problema e proposta di un trial randomizzato del Lap Group Roma.

More than 10 years after its appearance in clinical practice, laparoscopic cholecystectomy can now be considered the standard operation for gallstone disease. However, some aspects of this operation are still debated. The need to perform routine antibiotic prophylaxis in order to reduce the incidence of infectious complications is still a matter of controversy. International guidelines do not recommend its routine use. The evidence for this, however, is rather limited, because there are no randomized trials with a sufficient number of cases to avoid a type II error. The authors, on behalf of the Lap Group Roma, introduce the protocol of a multicenter prospective randomized controlled clinical trial designed to find a definitive answer to this problem.