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ALTEX ; 30(1): 74-103, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23338808

RESUMO

The Evidence-based Toxicology Collaboration (EBTC) was established recently to translate evidence-based approaches from medicine and health care to toxicology in an organized and sustained effort. The EBTC held a workshop on "Evidence-based Toxicology for the 21st Century: Opportunities and Challenges" in Research Triangle Park, North Carolina, USA on January 24-25, 2012. The presentations largely reflected two EBTC priorities: to apply evidence-based methods to assessing the performance of emerging pathway-based testing methods consistent with the 2007 National Research Council report on "Toxicity Testing in the 21st Century" as well as to adopt a governance structure and work processes to move that effort forward. The workshop served to clarify evidence-based approaches and to provide food for thought on substantive and administrative activities for the EBTC. Priority activities include conducting pilot studies to demonstrate the value of evidence-based approaches to toxicology, as well as conducting educational outreach on these approaches.


Assuntos
Toxicologia/métodos , Toxicologia/normas , Animais , Biomarcadores , Ensaios de Triagem em Larga Escala , Humanos , Reprodutibilidade dos Testes , Toxicologia/legislação & jurisprudência , Estados Unidos , United States Food and Drug Administration
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