Role of Medicinal Herbs in Periodontal Therapy: A Systematic Review.

Aims and Objectives: The use of medicinal herbs to prevent gingival and periodontal diseases has become increasingly popular due to their anti-inflammatory and antioxidant properties. This systematic review aims to provide the current literature to validate the traditional use of medicinal herbs in the management of gingival and periodontal diseases. Materials and Methods: An online literature search was conducted to identify research papers published from 2010 to 2022 in three major scientific databases, PubMed, Scopus, and Web of Science, in June 2022. Original research studies, case reports, and systematic reviews on medicinal plants' application in oral health care were selected to be included in this systematic review. Only high-quality articles identified in the quality assessment were included for evidence synthesis. Results: Initial keyword research yielded 726 free-text articles published between 2010 and 2022. Of these, 14 articles (8 research papers and 6 reviews) were included for evidence synthesis. The review's findings indicate that the antibacterial property of medicinal plants is due to their alkaline nature and prevents plaque and calculus formation by maintaining acid-alkali balance in saliva. Various parts of medicinal plants help maintain periodontal health. Glycyrrhiza glabra, Ficus religiosa, and Plantago major effectively inhibit primary plaque colonizers and periodontal pathogens. Medicago sativa, Aloe barbadensis Miller, and Trifolium pratense have excellent applications in treating periodontal diseases. Mangifera indica, Pongamia pinnata, the husk of Cocos nucifera, the root of G. glabra and Curcuma longa, leaves of Psidium guajava and Azadirachta indica, fruits of Citrus medica and Punica granatum, Ocimum Moringa oleifera extract, and pomegranate peel extract can serve as a promising alternative in managing chronic gingivitis. Conclusion: The anti-inflammatory, antioxidant, antibacterial, and astringent action of extracts obtained from various parts of medicinal plants make them effective in reducing gingival and periodontal diseases. Herbal medicine may be a viable alternative to contemporary pharmaceuticals as an adjuvant to scaling and root planning procedures.

Systematic Reviews in Dental Research: A Bibliometric Analysis of Contribution from Indian Dentists During 1948-2022.

Aims and Objective: Although systematic reviews (SRs) are the backbone of evidence-based dentistry, they have appeared infrequently in dental literature and their importance may not be recognized by dentists. So, this study aimed to identify SRs in dental research contributed by Indian dentists to the PubMed database during 1948-2022 and describes their epidemiological and descriptive characteristics. Materials and Methods: An electronic search of the PubMed database was performed from 1948 through September 2022. SRs were considered for inclusion if they were related to oral health and published by Indian dentists as the first author. From this collection, the following characteristics of SRs were described: name of the journal, type of journal (e.g., general dentistry, specialty dentistry, non-dental), year of publication, author's affiliation, and focus of the SR. Results: The search identified 439 SRs in dentistry indexed in the PubMed database during 1948-2022. There were only 5 SRs published from 2007 to 2010 with maximum publications during the year 2021 (n = 114; 25.97%). About 32.35% of the SRs (n = 142) were published in 10 journals with the maximum contribution from the Journal of Conservative Dentistry (n = 22; 5.01%). The majority of the SRs were published in the field of Pedodontics and Preventive Dentistry (n = 72; 16.40%), followed by Conservative Dentistry and Endodontics (n = 63; 14.35%). Conclusion: The contribution of SRs in dental research from India is small but growing. There is a clear need to improve SRs in dental research qualitatively and quantitatively.

Optimizing dimensional changes of soft tissue in alveolar ridge preservation using rotational palatal pedicle flap in posterior maxilla - A randomized controlled clinical trial.

Background: After tooth extraction, it is critical to maintain alveolar bone proportions as well as soft tissue integrity for rehabilitation. The common procedure for closing the socket is a coronally advanced flap, however, it compromises the keratinized tissue dimensions. As a result, the current study's goal is to assess and compare the soft tissue dimensional alterations caused by the new palatal rotational pedicle flap versus the conventional coronally advanced flap as an adjunct to alveolar ridge preservation. Materials and Methods: Fifty-four participants requiring extraction of single maxillary posterior teeth were randomized into two groups. While both groups used a 1:1 mixture of demineralized freeze dried bone allograft and platelet rich fibrin to preserve the ridge after atraumatic extraction, the control group used a coronally advanced flap to seal the socket, whereas the test group used a rotational palatal pedicle flap to close the socket. At baseline, 3 and 6 months after surgery, the clinical parameters, i.e., vertical ridge height (VRH), horizontal ridge width (HRW), width of keratinized gingiva (WKG), thickness of keratinized gingiva (TKG), and papillary height (PH) were measured. Results: Intergroup comparison demonstrated a significantly greater gain in WKG (P = 0.001), TKG (P = 0.029) and PH (P = 0.021) in the test group. The VRH and HRW, on the other hand, were preserved in both groups. The data were analyzed using unpaired t-test for intergroup and analysis of variance for intragroup comparison. Conclusion: Both groups effectively preserved hard tissue dimensional changes, with the test group showing superior soft tissue enhancement.

Comparison of clinical and radiological outcomes using crestal approach sinus kit and piezoelectric surgery for sinus membrane elevation: A prospective clinical trial.

Background: To overcome the drawbacks of sinus floor augmentation procedures newer surgical techniques to reduce sinus perforation such as crestal approach sinus kit (CAS) and piezosurgery, which are minimally invasive procedures enabling uncomplicated sinus elevation have evolved. The aim of the present study was to investigate the performance of CAS kit compared to piezosurgery during maxillary sinus membrane elevation. Materials and Methods: A total of 40 subjects requiring maxillary sinus membrane augmentation for rehabilitation with implant prosthesis in posterior maxilla were included in the study. The current study was a prospective clinical trial where osteotomy and sinus elevation was done using CAS kit in Group 1 and piezosurgery in Group 2. Platelet-rich fibrin was placed in osteotomy site and dental implants were inserted. Implant stability was evaluated at baseline and 3 months. Crestal bone loss was measured at 3, 6, and 12 months. Apical bone gain was measured at 6 and 12 months. Intragroup comparison of the study groups was done by Paired t-test, ANOVA test, and Friedman test. Intergroup comparison was done by unpaired t-test and Mann-Whitney U-test. P < 0.05 was considered statistically significant. Results: Implant stability improved in both the groups, i.e., 79.2 ± 5.02 and 79 ± 5.31 in Group 1 and Group 2, respectively, at 3 months. Intergroup comparison showed no difference in all parameters; however, crestal bone loss was greater in piezosurgery group with a mean difference of 0.74 mm. Conclusion: Both CAS and piezosurgery groups showed definitive improvement in all parameters. CAS group resulted in added benefits in terms of less crestal bone loss and intraoperative surgical time compared to piezosurgery group.

Emotional Health Status of Postgraduate Students of Periodontics in India During COVID Health Crisis-A Questionnaire-Based Study.

Dental students, especially postgraduate students present a higher risk of getting infected because of their close contact with the patients during this pandemic. The objectives of the study include (a) the reasons for postgraduate students' altered emotional status during coronavirus (COVID-19) infection. (b) To assess the kind of infection protocols adopted. (c) To assess the impacts of postgraduate students' emotional status on treating patients with periodontal problems during the COVID-19 lockdown period from March 2020 to December 2020. The emotional status of postgraduate students was assessed in 2 phases that are at the initial phase of COVID infection and lockdown and the second phase when the lockdown was prolonged. Questionnaires were distributed to the Postgraduate students of periodontics all over India to assess their level of awareness of COVID infection, type of infection control measures followed during the pandemic period, as well as the outpatient turnout during the lockdown period. Results of this study stated that more than 80% of students addressed the decline in the number of patients to surgical clinics, 76.3% of postgraduates were worried about themselves and their families due to the pandemic situation. Surprisingly, 74.3% of them even worried about losing their expertize or skills due to a long lockdown period. Dental postgraduates all over India are willing to treat their patients during the period of a pandemic but in strict compliance with infection control guidelines. This study assessed the emotional responses of the postgraduates during the pandemic through the questionnaire and concluded that all the professionals are ready to resume their clinical activities with adequate guidelines provided.

Single-flap versus double-flap approach for periodontal pocket reduction in supraosseous defects: a comparative study.

PURPOSE: The single-flap approach (SFA) is a minimally invasive technique with limited mucoperiosteal flap elevation to gain access to the buccal/palatal aspects, thus limiting post-surgical complications. The purpose of the present study was to gain insights into the impact of the SFA over the double-flap approach (DFA) on periodontal flap treatment outcomes and patient compliance in terms of discomfort and time taken for surgical procedures. METHODS: Twenty patients with persistent probing pocket depths of ≥5 mm were scheduled for the SFA (test site) and for the DFA (control site). All the clinical periodontal parameters were recorded at baseline, 3 months, and 6 months. Radiographic bone level (cone-beam computed tomography) was evaluated at baseline and 6 months. Patients' postoperative pain perception and wound healing were also assessed. RESULTS: The SFA showed a significant reduction in periodontal pocket depth, gain in clinical attachment level (CAL), and gain in bone level when compared with the DFA. The SFA substantially improved wound healing and induced less postoperative pain than the DFA. CONCLUSIONS: The SFA resulted in substantial improvement in the composite outcome measures, as shown by a reduction in pocket depth with minimal gingival recession, gain in CAL, early wound healing, less postoperative discomfort, and better patient-centered outcomes. TRIAL REGISTRATION: Clinical Trials Registry-India Identifier: CTRI/2018/05/013562.

Role of Communication, Professionalism, and Clinical Care Skills of Postgraduate Students on Patients Recall Visits in Dental School-An Observational Study.

Preservation of periodontal health after periodontal therapy is paramount for the complete elimination of periodontal diseases. In most of the Dental Schools, recall appointments are considerably low, and in particular, to the Department of Periodontics, the compliance to recall visits by the patients diagnosed with periodontal disease is still inadequate. Faculty from the Department of Periodontics framed new criteria to follow in the comprehensive clinics by the postgraduate students. The criteria include communication, intraoral examination skills, and professionalism toward dental patients. Faculty in each comprehensive dental clinic observed the clinical encounters of postgraduate students with patients and provided the feedback. The study conducted from May 2018 to April 2019, and the patients attended were 1164 of 1544. Unattended patients were 380 of 1544. Effective evaluation of the feedback provided by faculty and communication with both the postgraduate students and unattended patients resulted in further improvement in recall, that is, 151 of 380 patients. Reframed criteria, direct observation of the postgraduate students by faculty during patients interaction, assessment of feedback forms, and immediately modifying the student's way of communication allowed maximum recall visits to the Department of Periodontics.

Ethical guidelines, animal profile, various animal models used in periodontal research with alternatives and future perspectives.

Laboratory animal models serve as a facilitator to investigate the etiopathogenesis of periodontal disease, are used to know the efficacy of reconstructive and regenerative procedures, and are also helpful in evaluation of newer therapeutic techniques including laser and implant therapies prior to application in the human beings. The aim of this review is to know the different animal models used in various specialties of dental research and to know the ethical guidelines prior to the usage of experimental models with main emphasis on how to refine, replace, and reduce the number of animal models usage in the laboratory. An online search for experimental animal models used in dental research was performed using MEDLINE/PubMed database. Publications from 2009 to May 2013 in the specialty of periodontics were included in writing this review. A total of 652 references were published in PubMed/MEDLINE databases based on the search terms used. Out of 245 studies, 241 were related to the periodontal research published in English from 2009 to 2013. Relevant papers were chosen according to the inclusion and exclusion criteria. After extensive electronic and hand search on animal models, it has been observed that various animal models were used in dental research. Search on animal models used for dental research purpose revealed that various animals such as rats, mice, guinea pigs, rabbit, beagle dogs, goats, and nonhuman primates were extensively used. However, with the new advancement of ex vivo animal models, it has become easy to investigate disease pathogenesis and to test the efficacy of newer therapeutic modalities with the reduced usage of animal models. This review summarized the large amount of literature on animal models used in periodontal research with main emphasis on ethical guidelines and on reducing the animal model usage in future perspective.

Combination of inflammatory and amlodipine induced gingival overgrowth in a patient with cardiovascular disease.

Gingival overgrowth (GO) is among one of the most important clinical features of gingival pathology frequently seen in periodontal clinic. Amlodipine is a comparatively new calcium channel blocker and is being used with increasing frequency in the management of hypertension and angina. A 48-year-old Indian woman who was on amlodipine for 3 years for hypertension reported to the department of periodontics with the complaint of swollen, un esthetic gums. The patient developed GO 6 months before her first visit to dental hospital. She developed GO very rapidly due to the increase in amlodipine dose due to the severe angina attack 6 months before and due to the use of cholesterol (CHO) lowering drug. The main aim of the case report is to study the severity of amlodipine induced GO in a patient with cardiovascular disease (CVD) and to identify the role of subgingival microorganisms on inflammatory gingival enlargement in the same patient. The severity and rapidity of gingival enlargement in this report could have been triggered by doubling the dose of amlodipine and concomitant use of CHO lowering drug.

Microbiological tests to identify a link between periodontitis and acute myocardial infarction-an original research.

BACKGROUND AND OBJECTIVES: Gingival and periodontal diseases are associated with specific bacterial infections. The main aim of the study was to know whether the periodontitis is associated with an increased risk for acute myocardial infarction (AMI) and to know the distribution of Porphyromonas gingivalis in patients with acute myocardial infarction associated with chronic periodontitis and acute myocardial infarction Groups. MATERIALS AND METHODS: Out of 50 patients, 20 were diagnosed as acute myocardial infarction associated with chronic periodontitis (Group I), twenty patients were suffering from AMI (Group II) and 10 patients were healthy (control Group III). RESULTS AND CONCLUSION: Periodontal pathogens were identified by phenotypic, enzymatic and hybridization methods. The total bacterial load and the number of Porphyromonas gingivalis pathogens were more in Group I when compared to Group II and Group III. Thus, the present study confirmed an association between periodontitis and AMI.