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1.
Eur J Cancer ; 138: 11-18, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32829104

RESUMO

The United Kingdom head and neck mucosal melanoma guideline development group used an evidence-based systematic approach to make recommendations in key areas of uncertainty in the field, including accurate diagnosis and staging; the appropriate treatment pathway including surgery, adjuvant radiation and new systemic treatments, such as targeted agents and immunotherapy; and the surveillance of patients after treatment. The guidelines were sent for international peer review and have been accredited by the National Institute for Health and Care Excellence. A summary of key recommendations is presented. The full documents are available on the Melanoma Focus website (https://melanomafocus.com/activities/mucosal-guidelines/mucosal-melanoma-resources/).


Assuntos
Neoplasias de Cabeça e Pescoço/terapia , Melanoma/terapia , Guias de Prática Clínica como Assunto , Terapia Combinada , Neoplasias de Cabeça e Pescoço/patologia , Humanos , Excisão de Linfonodo , Melanoma/patologia , Recidiva Local de Neoplasia , Estadiamento de Neoplasias , Biópsia de Linfonodo Sentinela , Reino Unido
2.
Eur Eat Disord Rev ; 19(2): 112-20, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-20669151

RESUMO

OBJECTIVE: Poor problem-solving and low self-esteem are frequently cited as significant factors in the development and maintenance of anorexia nervosa. The current study examines the multi-dimensional elements of these measures and postulates a model whereby self-esteem mediates the relationship between social problems-solving and anorexic pathology and considers the implications of this pathway. METHOD: Fifty-five inpatients with a diagnosis of anorexia nervosa and 50 non-clinical controls completed three standardised multi-dimensional questionnaires pertaining to social problem-solving, self-esteem and eating pathology. RESULTS: Significant differences were yielded between clinical and non-clinical samples on all measures. Within the clinical group, elements of social problem-solving most significant to anorexic pathology were positive problem orientation, negative problem orientation and avoidance. Components of self-esteem most significant to anorexic pathology were eating, weight and shape concern but not eating restraint. The mediational model was upheld with social problem-solving impacting on anorexic pathology through the existence of low self-esteem. CONCLUSION: Problem orientation, that is, the cognitive processes of social problem-solving appear to be more significant than problem-solving methods in individuals with anorexia nervosa. Negative perceptions of eating, weight and shape appear to impact on low self-esteem but level of restriction does not. Finally, results indicate that self-esteem is a significant factor in the development and execution of positive or negative social problem-solving in individuals with anorexia nervosa by mediating the relationship between those two variables.


Assuntos
Anorexia Nervosa/psicologia , Modelos Psicológicos , Resolução de Problemas , Autoimagem , Comportamento Social , Adolescente , Adulto , Estudos de Casos e Controles , Feminino , Humanos , Masculino , Inquéritos e Questionários , Adulto Jovem
3.
Eur Eat Disord Rev ; 18(1): 22-32, 2010 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-19827014

RESUMO

OBJECTIVE: Parental relationships and maladaptive problem solving have been associated with anorexic symptomatology. This study investigates the relationship between perceived parental bonding, social problem solving and eating psychopathology. METHODS: Forty three female inpatients with anorexia nervosa and 76 student controls were assessed using the Parental Bonding Instrument, the Social Problem Solving Inventory and the Eating Disorders Examination or the Eating Disorders Examination-Questionnaire. RESULTS: The anorexic group reported significantly lower levels of parental care than the student control group and used more negative and avoidance style coping. In the anorexic group, disordered eating was significantly correlated with low maternal care and high control. Maternal bonding was found to mediate the relationship between avoidance style coping and eating pathology. CONCLUSIONS: Findings suggest a relationship between maternal bonding, the use of maladaptive problem solving techniques and eating disorder pathology in inpatients with anorexia nervosa.


Assuntos
Anorexia Nervosa/psicologia , Comportamento Alimentar/psicologia , Apego ao Objeto , Relações Pais-Filho , Resolução de Problemas , Comportamento Social , Adaptação Psicológica , Adulto , Anorexia Nervosa/diagnóstico , Imagem Corporal , Feminino , Humanos , Pacientes Internados , Inventário de Personalidade , Análise de Regressão , Percepção Social , Inquéritos e Questionários
4.
Eur Eat Disord Rev ; 15(1): 70-7, 2007 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-17676675

RESUMO

OBJECTIVE: Research examining cognitive and behavioural determinants of anorexia is currently lacking. This has implications for the success of treatment programmes for anorexics, particularly, given the high reported dropout rates. This study examines two-dimensional self-esteem (comprising of self-competence and self-liking) and social problem-solving in an anorexic population and predicts that self-esteem will mediate the relationship between problem-solving and eating pathology by facilitating/inhibiting use of faulty/effective strategies. METHOD: Twenty-seven anorexic inpatients and 62 controls completed measures of social problem solving and two-dimensional self-esteem. RESULTS: Anorexics scored significantly higher than the non-clinical group on measures of eating pathology, negative problem orientation, impulsivity/carelessness and avoidance and significantly lower on positive problem orientation and both self-esteem components. In the clinical sample, disordered eating correlated significantly with self-competence, negative problem-orientation and avoidance. Associations between disordered eating and problem solving lost significance when self-esteem was controlled in the clinical group only. Self-competence was found to be the main predictor of eating pathology in the clinical sample while self-liking, impulsivity and negative and positive problem orientation were main predictors in the non-clinical sample. DISCUSSION: Findings support the two-dimensional self-esteem theory with self-competence only being relevant to the anorexic population and support the hypothesis that self-esteem mediates the relationship between disordered eating and problem solving ability in an anorexic sample. Treatment implications include support for programmes emphasising increasing self-appraisal and self-efficacy.


Assuntos
Anorexia Nervosa/psicologia , Resolução de Problemas , Autoimagem , Comportamento Social , Adolescente , Adulto , Estudos de Casos e Controles , Estudos Transversais , Feminino , Humanos , Análise de Regressão
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