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1.
Cureus ; 16(4): e57910, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38725795

RESUMO

BACKGROUND: "Healthy aging" is a major public health challenge, as the prevalence and incidence of diseases are much higher in older people. Among them, diabetes mellitus, hypertension (HTN), and cardiovascular illnesses are the most prevalent chronic ailments. A complete blood count test can give an overall picture of a patient's health status because abnormal counts might indicate the presence of many different types of disease. Using advanced hematology analyzers, a typical microscopic examination of a peripheral blood smear can yield vital information about the clinical state of the patient. The objective of the study was to investigate the hematological parameters in the elderly population in a tertiary care hospital, utilizing a five-part cell counter and a peripheral smear test. METHOD: A cross-sectional study was conducted at a tertiary care institute on 188 patients aged 60 years and above attending the outpatient department for two years. The routine complete blood count and differential count were determined on the Siemens Advia 2120 analyzer. All the data were collected and entered into the data sheets. Appropriate statistical analysis was carried out to interpret the results. RESULTS: HTN, diabetes mellitus, cardiovascular disease (CVD), and generalized weakness were the most common conditions affecting our senior group. Decreased Hb was positively correlated with widespread weakness. Total leukocyte count (TLC) was found to be more prevalent in people with CVD and HTN. A sizable share of the elderly population who had diabetes mellitus and CVD showed an elevated red cell distribution width (RDW) percentage. CONCLUSION: The results indicated a significant deviation from normal hematological parameters, which were associated with various health issues. These parametric associations can be used as risk indicators, which can help healthcare professionals ensure the good health of the geriatric population.

2.
Cureus ; 15(1): e33208, 2023 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-36733580

RESUMO

Dermatofibrosarcoma protuberans is a rare, low-grade dermal soft-tissue tumor with a high propensity for recurrence but a low propensity for metastatic spread. It mostly affects the head, neck, proximal extremities, and trunk. We report a case of dermatofibrosarcoma protuberans over the right lumbar region. The patient presented with swelling in the right lumbar region measuring 3 cm × 3 cm. The local region ultrasonography (USG) revealed a well-defined hypoechoic lesion in the subcutaneous area. The patient was provisionally diagnosed with a peripheral nerve sheath tumor under evaluation. USG-guided fine needle aspiration cytology (FNAC) suggested a spindle cell tumor. Wide local excision of the tumor was performed. Monomorphic spindle cells in a storiform pattern were observed by histological evaluation. The neighboring adipose tissue was invaded by the tumor cells in a honeycomb-shaped pattern. The histological features were suggestive of Dermatofibrosarcoma Protuberans. Due to the high likelihood of recurrence, it is crucial to monitor these patients for an extended period of time.

3.
Cureus ; 14(11): e31275, 2022 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-36505120

RESUMO

Filariasis is a global public health problem. We routinely examine it in peripheral smears made from samples collected during the night. Though the prevalence is high, microfilariae are rarely found in cytology smears. A lymph node presenting as a filarial nodule is an unusual occurrence. Also, lymph node fine needle aspiration cytology (FNAC) with a finding of microfilariae is uncommon. We would like to report the case of incidental microfilariae finding in a patient who presented with a supraclavicular lymph node mass. The patient presented with a right supraclavicular lymph node mass of size 2 cm × 2 cm and severe fever during the night for six months. The USG-neck region revealed enlarged lymph nodes in the right supraclavicular region. She was provisionally diagnosed as a case of cervical lymph node swelling under evaluation. However, on ultrasound-guided FNAC of the lymph node, microfilariae were found incidentally. In cases where clinical presentations of filariasis are absent, FNAC may aid in the diagnosis of microfilariae in the lymph node.

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