1.
Curr Opin Pharmacol
; 48: 1-7, 2019 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30921690
RESUMO
New anti-infective drugs are an unmet necessity of modern medicine. The use of â¼omics technologies has exponentially increased the knowledge on active anti-infective structures, where to search for them and their mechanisms of action. Research involving extreme and unique environments (such as endophytes) revealed their potential for many yet unknown active molecules. This work intends to review a recent research involving discovery of secondary metabolites with an established anti-infective action which was mediated by one of the â¼omics sciences: genomics, proteomics, transcriptomics, metabolomics, glycomics or their combinations, as well as the software at the base of these discoveries.