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INTRODUCTION: Preterm premature rupture of membranes (PPROM) is the spontaneous rupture of the fetal membranes before the completion of 37 weeks of pregnancy. PPROM occurs in 3% of pregnancies. METHODOLOGY: This prospective observational study was conducted between September 2019 and March 2021, involving 150 antenatal patients attending our outpatient department or labor room. All pregnant women with a singleton pregnancy between 28 and 37 weeks of gestational age with PPROM were included in our study. RESULTS: A total of 44% of women were admitted to the hospital within 6-11 hours of the onset of PPROM, while 34% of women were admitted within five hours and 15.33% were admitted within 12-23 hours of the onset of PPROM. The most common organisms isolated in high vaginal swabs were Enterococcus faecalis (18%), Escherichia coli (12%), Staphylococcus aureus (12.66%), Staphylococcus haemolyticus (6.66%), and Candida albicans (4.66%). Around 74.66% of women were delivered within 24 hours of the onset of PPROM, whereas only 2.6% of patients were delivered after 72 hours and the rest 34% were delivered between 25 and 72 hours. Of our study subjects, 10% were febrile, 4% were having urinary tract infections, 2.5% had postpartum hemorrhage, and 2% had chorioamnionitis. As far as neonatal morbidity and mortality are concerned, birth asphyxia and jaundice were seen in 12% of patients each, whereas septicemia was found in 4% of study subjects. CONCLUSION: Owing to the association of higher maternal and perinatal morbidity and mortality, cases, especially in the early PPROM group, should be strictly monitored for clinical and laboratory signs of chorioamnionitis while opting for conservative management.
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Introduction A paucity of data exists regarding pregnancy outcome data in women with polycystic ovarian syndrome (PCOS). Therefore, we conducted this study to compare the pregnancy outcomes of women with and without in Indian population. Materials and methods A total of 102 antenatal pregnant women aged between 18 and 45 years were included in this study conducted at the Department of Obstetrics and Gynecology, Pradyumna Bal Memorial Hospital, Kalinga Institute of Medical Sciences, Bhubaneswar, India. Fifty-one women had PCOS, and 51 women served as controls. We recorded patient demographic, clinical, menstrual, and pregnancy data for each group. All participants were monitored until delivery, and we recorded maternal outcomes, including spontaneous abortion, preterm birth, gestational diabetes mellitus (GDM), and pregnancy-induced hypertension (PIH). We used IBM SPSS Statistics version 20.0 for Windows (Armonk, NY: IBM Corp.) for statistical analysis and the chi-square test to analyze relationships in categorical variables. Results Most participants were aged between 20 and 30 years (64.7%). A high body mass index (BMI) was twice as common in women with PCOS than the control group. Most women with PCOS with pregnancy complications were overweight (62.7%) with a BMI of 25 to 29.9 kg/m2. A majority of women in the PCOS group (86.3%) required reproductive technology assistance, while none in the control group needed the same type of assistance. In the PCOS group, spontaneous abortions (SAB) occurred in 5.9%, GDM occurred in 17.6%, PIH in 21.6%, and preterm births in 33.3%. By contrast, the control group saw SAB occur in only 3.9%, GDM occurred in 9.8%, PIH was identical in 21.6%, and preterm births occurred in 17.6% of women without PCOS. Cesarian delivery occurred in 64.7% of women with PCOS, while only 39.2% of women without PCOS had cesarian delivery was statistically not significant. Conclusion We conducted this study to assess the impact of PCOS on pregnancy against pregnant women without PCOS. Pregnant women with PCOS were more likely to experience complications such as SAB, GDM, and preterm birth than pregnant women without PCOS. Therefore, pregnancies in women with PCOS are high-risk pregnancies that require frequent and timely antenatal care.
