[State of antioxidant and oxygen transport system of the blood in the process of adaptation of the body to hypoxic hypoxia]. / Stan antyoksydantnoï ta kysnevo-transportnoï system krovi v protsesi adaptatsiï orhanizmu do hipoksychnoï gipoksiï.

This article shows that in oxygen transported and antioxidative systems considerable changes take place during dynamic of adaptation to oxygen deficiency of inhaled air (every day 4 hours stay of animals in barochamber under pO2 7.45 kPa during 12 days). Single influence of hypoxic factor induced in erythrocytes peripheral blood increasing of haemoglobin affinity to oxygen, decreasing SOD and catalase activity on the background of increasing of malon aldehyde level. On 12-th day of adaptation of animals contents of TBA-active products in erythrocytes is saved on high level, activity of antioxidative enzymes is approached to original meanings, haemoglobin affinity to oxygen is decreased in comparison with control. Detected increasing content of creatine in erythrocytes during dynamic of rat adaptation to hypoxic hypoxia witnessed about erythropoiesis activation and quickened exit out of marrow young forms of erythrocytes.

[A comparative analysis of the oxygen-binding and antioxidant properties of the blood of laboratory animals and the muskrat Ondatra zibethica]. / Sravnitel'nyi analiz kislorodsviazyvaiushchikh i antioksidantnykh svoistv krovi laboratornykh zhivotnykh i ondatry Ondatra zibethica.

Close correlation of oxygen-binding properties of haemoglobin and the content of malonyl dialdehyde (MDA) in animal blood plasma was shown. The higher the affinity of haemoglobin to O2, the lower MDA level in the blood plasma. For the muskrat Ondatra zibethica, representing diving animals, MDA content is lower and catalase activity is higher compared with the laboratory rat.