RESUMO
(1) Background. Patients with bilateral vestibular disease (BVD) experience oscillopsia with a detriment to visual acuity (VA). This VA is driven mainly by the VOR that has two components: rotational and translational. VA can be tested by using dynamic visual acuity (DVA) on a treadmill because both systems are activated. The aim of this study is to compare VA before and after chronic electrical stimulation of the otolith organ. (2) Materials and Method. Five patients suffering from bilateral vestibular dysfunction (BVD), previously implanted with a new vestibular implant prototype, were included in this study with the aim to check VA with and without vestibular implant use (W and W/O) in static, 2 km/h and 4 km/h walking situations. DVAtreadmill was measured on a treadmill with a dynamic illegible E (DIE) test in static and dynamic conditions (while walking on the treadmill at 2 and 4 km/h). The DVA score was registered in a logarithm of the minimum angle of resolution (LogMAR) for each speed. In addition, every patient completed the oscillopsia severity questionnaire (OSQ) and video head impulse test (vHIT) before and after activation of the vestibular implant. (3) Results. The analysis shows a significant difference in OSQ scores and DVA with an improvement in dynamic conditions. Organized corrective saccades during the use of a vestibular implant with no changes in gain were also detected in the video head impulse tests (vHIT). (4) Conclusion. The vestibular implant with otolithic stimulation offers changes in the response of DVA, which makes this paper one of the first to address the possible restoration of it. It is not possible to rule out other contributing factors (presence of covert saccades, somatosensory system, ). More work seems necessary to understand the neurophysiological basis of these findings, but this implant is added as a therapeutic alternative for the improvement of oscillopsia.
RESUMO
New cochlear implant (CI) electrode arrays provide softer insertion dynamics; however, due to their high flexibility, the possibilities of fold-overs or intraoperative displacements must be taken into account. The position of each individual electrode can only be determined by using high-resolution computed tomography or cone-beam CT. The trans-impedance matrix test (TIM) is an electrophysiological method based on electric field imaging that can provide images of electrode position and electrode folding. OBJECTIVE: In this experimental research, we evaluated the result of TIM as a method of monitoring cochlear insertion for a precurved slim modiolar electrode array in fresh human temporal bones by analyzing the transimpedance matrix patterns and their correlation with electrode position using high-resolution computed tomography. MATERIAL AND METHODS: Sixteen slim modiolar electrode arrays were inserted into eight fresh Human Temporal Bones. Eight electrodes were inserted according to the correct methodology of insertion, and eight were intentionally folded over. After all insertions, a trans-impedance matrix analysis and a Cone Beam CT (CBCT) were performed in each temporal bone. RESULTS: If we correlated the TIM patterns with the radiological electrode position, we observed that better electrode intracochlear positions indicated more "homogeneous" TIM patterns (intracochlear voltage dropped monotonically as the distance between stimulation and recording contact increased, both toward the apex and toward the base). A correlation where fold-over was detected in the TIM results was found in all eight temporal bone radiological findings. CONCLUSIONS: Trans-Impedance Matrix patterns were correlated with the radiological CI electrode position. When a tip fold-over appeared, a matrix with a secondary ridge in addition to the primary ridge was observed in all cases. TIM can be an effective method in the control of electrode positioning.
