1.
J Biotechnol
; 21(1-2): 173-85, 1991 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-1367688
RESUMO
Enzyme sensors for glucose, lactate and glutamine were connected via flow-injection analysis (FIA) devices to two different bioprocesses. They were used for on-line process control of perfused bioreactor systems containing mammalian cell lines producing a monoclonal antibody and recombinant interleukin-2. The biosensor system gives direct access to important process data which can be used as control parameters for long term cell cultivation systems.