RESUMO
OBJECTIVE: The aim of this work was to review the incidence of monoclonal gammopathy of undetermined significance (MGUS) and complications in kidney transplant (KT) patients at the Puerta del Mar Hospital in Cádiz, Spain. This diagnosis was not considered to be a contraindication for transplantation. METHODS: To estimate the incidence of MGUS in KT patients we used the database of our hospital, which included 1,016 patients who received a KT from 1992 to 2012 with a median follow-up of 30 months. The incidence of MGUS in non-transplant patients was estimated from the literature. RESULTS: Out of 1,016 KT patients, 16 developed MGUS; 10 (72.5%) were >50 years old. Two patients developed post-transplantation lymphoproliferative disorders. No cases of progression to multiple myeloma or amyloidosis were seen during immune suppression therapy or after. CONCLUSIONS: MGUS was >100 times more frequent in KT recipients than in the general population (P < .05). But in contrast to MGUS in general population, progression to plasma cell dyscrasia in these patients was absent and its incidence is unknown in KT patients.
Assuntos
Transplante de Rim , Gamopatia Monoclonal de Significância Indeterminada/etiologia , Complicações Pós-Operatórias , Adulto , Idoso , Feminino , Seguimentos , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Gamopatia Monoclonal de Significância Indeterminada/epidemiologia , Avaliação de Resultados em Cuidados de Saúde , Complicações Pós-Operatórias/epidemiologia , Estudos Retrospectivos , EspanhaRESUMO
El plasmocitoma solitario es un tumor poco frecuente de células plasmáticas que ocasionalmente puede aparecer en la región de la cabeza y el cuello. Por su presentación inicial debe diferenciarse del mieloma múltiple. Describimos un caso de plasmocitoma solitario de paladar y analizamos el papel de la tomografía por emisión de positrones con 18F-fluorodeoxy-glucosa en su estadificación inicial(AU)
Solitary plasmacytoma is an uncommon tumor of plasma cells that can appear in the head and neck. It must be differentiated from multiple myeloma because of its initial presentation. A case of solitary plasmacytoma on the palate is presented. Furthermore, role of 18F-fluorodeoxyglucose Positron Emission Tomography (18F-FDG-PET) in its initial staging is analyzed(AU)
Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Tomografia por Emissão de Pósitrons/métodos , Tomografia por Emissão de Pósitrons/tendências , Plasmocitoma/diagnóstico , Plasmocitoma/patologia , Mieloma Múltiplo/complicações , Mieloma Múltiplo/diagnóstico , Palato Mole/patologia , Diagnóstico Diferencial , Plasmocitoma , Mieloma Múltiplo , Palato MoleRESUMO
Solitary plasmacytoma is an uncommon tumor of plasma cells that can appear in the head and neck. It must be differentiated from multiple myeloma because of its initial presentation. A case of solitary plasmacytoma on the palate is presented. Furthermore, role of ¹8F-fluorodeoxyglucose Positron Emission Tomography (¹8F-FDG-PET) in its initial staging is analyzed.
