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JOP ; 11(2): 176-82, 2010 Mar 05.
Artigo em Inglês | MEDLINE | ID: mdl-20208331

RESUMO

Erlotinib has been FDA approved to be used in combination with gemcitabine as the first line treatment in advanced pancreatic cancer patients. Skin rash has been documented as one of the commonest adverse reactions in patients receiving erlotinib and other EGFR inhibitors. Draw back to this reaction leads to: 1) drug discontinuation or dose reduction; 2) impairs quality of life; and 3) Puts patients at risk of superinfection. Monitoring patients closely and initiating immediate skin care is recommended. However, patients forget how the rash started and when. No standard treatments exist secondary to the diversity of symptoms, variability and intermittent occurrence in relation to the cancer therapy. In addition, there is slow improvement with medical treatment. Also, patients need to make extra visits to doctor's office for skin management when in needed in addition to chemotherapy appointments. Late presentation for medical attention leading to complications, such as sepsis. We here experience a novel way of assessing and managing the skin rash using the electronic media. We suggest that electronic communication is of crucial importance to detect early, diagnose and treat anti-EGFR related skin rash in order to continue the benefit of anti-EGFR.


Assuntos
Carcinoma/tratamento farmacológico , Correio Eletrônico , Receptores ErbB/antagonistas & inibidores , Neoplasias Gastrointestinais/tratamento farmacológico , Neoplasias Pancreáticas/tratamento farmacológico , Inibidores de Proteínas Quinases/efeitos adversos , Dermatopatias/induzido quimicamente , Dermatopatias/terapia , Telecomunicações , Sistemas de Notificação de Reações Adversas a Medicamentos , Algoritmos , Recursos Audiovisuais , Comunicação , Continuidade da Assistência ao Paciente , Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/terapia , Eficiência , Acessibilidade aos Serviços de Saúde , Humanos , Cooperação do Paciente , Relações Médico-Paciente , Inibidores de Proteínas Quinases/uso terapêutico
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