1.
J Org Chem
; 85(16): 10719-10727, 2020 Aug 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32664733
RESUMO
A range of indolizine smoothly underwent visible-light-induced intermolecular [3+2] annulations with internal alkynes to afford pyrrolo[2,1,5-cd]indolizine in good to excellent yields with high regioselectivity. Through this cascade reaction, a series of fluoroactive fused indolizines with a large π-system were conveniently synthesized. The usage of visible light as energy source with air as a stoichiometric oxidant under simple conditions makes this process attractive and practical.