RESUMO
The purpose of this presentation has been to describe, in a very general way, the gynecologic problems of elderly women and of the system available to provide gynecologic services to them on an ambulatory basis. Several suggestions to improve care are made. Some can be implemented readily, but others will require new and additional personnel. I firmly believe that the care of aging women will soon require the creation of new facilities and development of new equipment and of new approaches much like the care of other special groups has required.
Assuntos
Envelhecimento , Assistência Ambulatorial , Ginecologia , Idoso , Pessoal Técnico de Saúde , Agendamento de Consultas , Feminino , Humanos , Profissionais de Enfermagem , Exame FísicoRESUMO
Normal pregnancy and delivery after chemotherapy and radiation of cerebral metastases in a case of choriocarcinoma is presented. The need of surgical approach to these lesions as proposed by Stilp and his group is questioned.
Assuntos
Neoplasias Encefálicas , Coriocarcinoma , Complicações na Gravidez , Neoplasias Uterinas , Adolescente , Neoplasias Encefálicas/terapia , Clorambucila/uso terapêutico , Coriocarcinoma/terapia , Dactinomicina/uso terapêutico , Quimioterapia Combinada , Feminino , Humanos , Metotrexato/uso terapêutico , Metástase Neoplásica , Gravidez , Complicações na Gravidez/terapia , Risco , Neoplasias Uterinas/terapiaAssuntos
Cistos Ovarianos/história , Neoplasias Ovarianas/história , Tumor Carcinoide/patologia , Carcinoma de Células Escamosas/patologia , Transformação Celular Neoplásica , Coriocarcinoma/patologia , Cisto Dermoide/complicações , Cisto Dermoide/patologia , Feminino , História do Século XVII , História do Século XVIII , História do Século XIX , História do Século XX , História Antiga , Humanos , Melanoma/patologia , Cistos Ovarianos/complicações , Cistos Ovarianos/patologia , Neoplasias Ovarianas/complicações , Neoplasias Ovarianas/patologia , Gravidez , Ruptura , Teratoma/etiologia , Teratoma/patologia , Anormalidade TorcionalRESUMO
There were 253 dermoid tumors of the ovary studied. Torsion of the pedicle with hemorrhagic infarction proved to be the most frequent complication; malignant change was the most lethal. Nine patients with malignant dermoid tumors, most of them with locally advanced disease, were treated with conservative surgery, radiation, and/or chemotherapy. The longest known survivor lived 3 years; most patients died within a year. It was concluded that a more aggressive surgical approach might salvage some patients with locally advanced malignant disease.
Assuntos
Cisto Dermoide/complicações , Neoplasias Ovarianas/complicações , Adolescente , Adulto , Idoso , Carcinoma de Células Escamosas/patologia , Cisto Dermoide/cirurgia , Feminino , Humanos , Íleo , Perfuração Intestinal/etiologia , Intestino Grosso , Fígado/lesões , Pessoa de Meia-Idade , Metástase Neoplásica , Complicações do Trabalho de Parto , Neoplasias Ovarianas/patologia , Neoplasias Ovarianas/cirurgia , Gravidez , Complicações na Gravidez , Ruptura Espontânea , Anormalidade Torcional/etiologia , Útero/lesõesAssuntos
Dispositivos Anticoncepcionais , Anticoncepcionais Orais/efeitos adversos , Estudos Prospectivos , Adulto , Fatores Etários , Neoplasias da Mama/induzido quimicamente , Escolaridade , Características da Família , Feminino , Neoplasias dos Genitais Femininos/induzido quimicamente , Humanos , Renda , Mestranol/efeitos adversos , Métodos , Noretinodrel/efeitos adversos , Ocupações , Paridade , Probabilidade , Porto Rico , Projetos de Pesquisa , Estatística como Assunto , Fatores de TempoRESUMO
PIP: 9634 patients (21-39 years, with at least 1 normal pregnancy) with no previous experience with oral contraceptives or IUDs, seen at clinics in Rio Piedras, Caguas, and Ponce, Puerto Rico from July 1961 to October 1969 to study their changing patterns in cervical cytology were divided randomly into 2 groups, of which 4846 were given oral contraceptive, Enovid, and 4788 provided with a vaginal contraceptive excluding IUDs, and followed for a period of 6 months-8 years. Separate Pap smears were obtained at admittance to the study by an endocervical aspiration with the pipette and cervical sample with Ayre spatula scraped over the cervico-columnar junction. The cervix was diagrammed showing any erosion. Schiller tests were done. Possible presence of Trichomonas vaginalis was treated. Repeat smears were done at 3-month intervals. 2129 oral patients and 2249 nonoral patients experienced either regression or progression in cytological patterns throughout the 8 years of observation. The analysis is divided into 3 groups, irrespective of the time at which they were observed. Of the 2129 oral patients showing a first change, 55.5% progressed to a higher Pap class, 44.5% regressed to a lower Pap class. In the nonoral group, 55.2% progressed and 44.4% regressed. 1255 patients had a second change: in the oral group, 37.5% progressed, 62.5% regressed. In the nonoral group, 36.7% progressed, 63.3% regressed out of 1258 patients. 690 oral patients showed a third change: 46.1% progressed and 53.9% regressed. Of the 718 nonoral patients 47.1% progressed and 52.9% regressed. There was no significant difference in the pattern of progression and regression between oral and nonoral groups. Oral contraceptives do not aggravate the conditions which lead to development of premalignant lesions in the uterine cervix.^ieng
Assuntos
Colo do Útero/efeitos dos fármacos , Dispositivos Anticoncepcionais/efeitos adversos , Anticoncepcionais Orais/efeitos adversos , Lesões Pré-Cancerosas/induzido quimicamente , Lesões Pré-Cancerosas/etiologia , Adulto , Colo do Útero/patologia , Ensaios Clínicos como Assunto , Feminino , Humanos , Mestranol/efeitos adversos , Noretinodrel/efeitos adversos , Teste de Papanicolaou , Lesões Pré-Cancerosas/patologia , Fatores de Tempo , Esfregaço VaginalAssuntos
Síndromes do Arco Aórtico , Complicações Cardiovasculares na Gravidez , Adulto , Feminino , Humanos , GravidezRESUMO
PIP: The effect of high-dose, long-term oral contraceptive use on thyroid function and thyroid disease was investigated. Between 1956 and 1962 there were 836 patients treated with Enovid. Initially doses of 10 mg were given, then 5 mg, and finally 2.5 mg. 53 patients used oral contraceptives continuously through a total of 8111 cycles with an average of 156 cycles and an average dose of 3.75 mg/day/cycle. These 53 women were studied for protein bound iodine (PBI), resin triiodothyronine (T3) uptake, total thyroxine (TT), free thyroxine level (FT), radioiodine uptake, and a thyroid scan. Fractional uptakes were done on some. The PBI, T3, TT, and FT tests were done at the Bio-Science Laboratories in California, the others at a local laboratory. Uptake values were abnormally low in 40% of patients. This finding had not been previously reported. Thyroid scannings for 48 patients showed 44 were normal. In 3 patients the thyroid appeared uniformly enlarged but this was not apparent on physical examination. A small cold area was noted in 1 thyroid. No nodule or other variation was found on physical examination. A combination of the PBI test and T3 would be most helpful in evaluating hypo or hyperthyroidism. In the presence of a nontoxic goiter the PBI would be normal or high and the T3 normal or low. Though individual tests showed alterations no definite e vidence of thyroid disease was found in the patients studied.^ieng