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1.
J Psychiatr Ment Health Nurs ; 30(3): 435-450, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-36066569

RESUMO

WHAT IS KNOWN ON THE SUBJECT: Nurses working at nursing homes can play a pivotal role in mental health as a high proportion of residents diagnosed with dementia are in these facilities. Many institutionalized residents diagnosed with dementia develop clinical complications and symptoms that reduce the quality of dying. A mixed-methods approach can help nurses with the difficult task of assessing the quality of dying among these residents and identify inconsistencies that cannot be found using scales alone, but no studies were found in this topic. WHAT THE PAPER ADDS TO EXISTING KNOWLEDGE: Through the Quality of dying in Long-Term Care Scale (QoD-LTC), nurses described symptom management, quality of care, and end-of-life appearance as adequate and end-of-life communication as lacking. Generally speaking, the scores on the scale were consistent with the data from semi-structured interviews conducted with nurses. In the semi-structured interviews, some of the concepts on the scale, including 'dignity', 'holistic' care, 'good relationships with healthcare professionals', and 'a peaceful death', are complex and not fully incorporated into nurses' practice in nursing homes when assessing residents diagnosed with dementia. This could be improved by using the SENSES Model or person-centred care frameworks. WHAT ARE THE IMPLICATIONS FOR PRACTICE?: There is evidence of shortcomings among professionals in the correct use of concepts linked to psychological wellbeing, communication, therapeutic relationship, safety and participation, preservation of dignity, decision-making, and resident autonomy, which can be addressed using specific theoretical approaches developed in the field of mental health nursing. ABSTRACT: Introduction The complex nature of end-of-life assessment of individuals diagnosed with dementia would benefit from a mixed-methods approach that simultaneously assess the perception and response of nurses to standardized tools. Aim/Question To examine nursing professionals' perceptions of the quality of dying among residents diagnosed with dementia using the Quality of Dying in Long-Term Care settings (QoD-LTC) questionnaire and to identify consistencies and inconsistencies in their narratives. Method Mixed-methods study using concurrent triangulation with data integration for results and interpretation. Nurses from eight nursing homes assessed 117 residents diagnosed with dementia who died in the previous 3 months using the QoD-LTC scale. After informed consent was obtained (nurses/caregivers), 17 semi-structured scale-based interviews were conducted. Results Symptom management, quality of care, and end-of-life appearance were found to be adequate, while end-of-life communication was deemed insufficient. The qualitative and quantitative data were consistent for most of the items on the QoD-LTC. Discussion Concepts such as dignity, holistic care, good relationships, and peaceful death are complex and not fully incorporated into professional practice. Implications for Practice The results highlight the need for greater involvement of mental health nurses as well as improved communication, training, and specific tools tailored to residents diagnosed with dementia.


Assuntos
Demência , Casas de Saúde , Humanos , Idoso , Assistência de Longa Duração , Cuidados Paliativos , Morte
2.
Stroke ; 53(11): 3485-3493, 2022 11.
Artigo em Inglês | MEDLINE | ID: mdl-35904017

RESUMO

The consequences of stroke can be devastating and include psychological distress, such as anxiety and depression, functional deficits, pain, and cognitive impairment. Symptoms are complex and impact not only the stroke survivor but may also be challenging for family caregivers. Studies have consistently demonstrated that mindfulness-informed interventions (MBI), such as mindfulness-based stress reduction and acceptance and self-compassion therapies, improve symptoms in a wide variety of clinical populations. However, research examining MBIs within the stroke population is in its infancy. Nurses, who have traditionally focused on holistic care delivery are in a unique position to incorporate MBIs throughout the stroke care continuum. In this topical review, we examine the literature related to the use of MBIs in stroke survivors and their family caregivers. We include a critical appraisal of existing literature, discuss nursing implications, and make recommendations for future research. Mindfulness-informed interventions are feasible and acceptable within the stroke population and may be an important complementary treatment to help stroke survivors and their families manage the consequences of stroke. We recommend further research to tailor MBI programs to the unique needs of stroke survivors and their family caregivers. In addition, nurses should consider opportunities to be trained in MBIs and incorporate these programs into their practice and research.


Assuntos
Atenção Plena , Acidente Vascular Cerebral , Humanos , Sobreviventes , Ansiedade/psicologia , Cuidadores/psicologia , Acidente Vascular Cerebral/terapia
3.
Rev. med. Risaralda ; 27(2): 161-169, jul.-dic. 2021. graf
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1365902

RESUMO

Resumen Introducción: La fístula colovesical es la unión entre la vejiga y el intestino grueso, se presenta en el 2% de los pacientes con enfermedad diverticular del colon, genera síntomas como neumaturia y fecaluria, asociados a infecciones urinarias recurrentes. Los pacientes se diagnostican mediante estudios imagenológicos y su tratamiento generalmente es quirúrgico. Objetivo: Reportar el caso de tratamiento laparoscópico de paciente con fístula colovesical secundaria a diverticulitis complicada. Caso clínico: Se presenta el caso de un paciente masculino de 69 años, con antecedente de enfermedad diverticular, cursando con infección de vías urinarias recurrentes, fecaluria y neumaturia. La cistoscopia no mostró trayecto fistuloso y la tomografía abdominopélvica mostró hallazgos inflamatorios y fístula colovesical asociada a diverticulitis complicada. Durante procedimiento laparoscópico se encuentra absceso pericólico sin evidencia del trayecto fistuloso, se realizó drenaje, sutura del colon e interposición del epiplón, sin resección intestinal. Paciente con adecuada evolución postoperatoria con egreso al sexto día. El objetivo del tratamiento quirúrgico se centra en el control de complicaciones generadas por los divertículos, en este caso, la fístula colovesical. Conclusiones: El procedimiento laparoscópico es de mínima invasión, no presenta la morbilidad que implica una resección de colon o una colostomía y se asocia con una recuperación funcional más rápida.


Abstract Introduction: The colovesical fistula is a junction between the urinary bladder and the large intestine. It occurs in 2% of patients with diverticular disease of the colon and generates symptoms such as pneumaturia and fecaluria associated with recurrent urinary tract infections. The patients are diagnosed by imaging studies and their treatment is usually surgical. Objective: To report the laparoscopic treatment administered to a patient that presented a case of colovesical fistula secondary to severe diverticulitis. Case report: The case of a 69-year-old male patient with a medical record of diverticular disease, who presented recurrent urinary tract infection, fecaluria, and pneumaturia is presented. The cystoscopy procedure showed no signs of anal fistula, and the abdominopelvic tomography showed signals of inflammations and colovesical fistula associated with complicated diverticulitis. During the laparoscopic procedure, a pericolic abscess was found without evidence of anal fistula. Drainage and suture of the colon and omentum interposition were performed without presenting intestinal resection. The patient had an adequate postoperative recovery and was discharged on the sixth day. The aim of this surgical treatment is focused on the control of medical complications caused by diverticulitis, in this case, colovesical fistula. Conclusions: This procedure is minimally invasive, and it is associated with a faster functional recovery since it does not present the morbidity of a colon resection or colostomy.

5.
J Clin Neurosci ; 91: 383-390, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-34373056

RESUMO

BACKGROUND AND PURPOSE: Early identification of large vessel occlusions (LVO) and timely recanalization are paramount to improved clinical outcomes in acute ischemic stroke. A stroke assessment that maximizes sensitivity and specificity for LVOs is needed to identify these cases and not overburden the health system with unnecessary transfers. Machine learning techniques are being used for predictive modeling in many aspects of stroke care and may have potential in predicting LVO presence and mechanical thrombectomy (MT) candidacy. METHODS: Ischemic stroke patients treated at Loyola University Medical Center from July 2018 to June 2019 (N = 286) were included. Thirty-five clinical and demographic variables were analyzed using machine learning algorithms, including logistic regression, extreme gradient boosting, random forest (RF), and decision trees to build models predictive of LVO presence and MT candidacy by area of the curve (AUC) analysis. The best performing model was compared with prior stroke scales. RESULTS: When using all 35 variables, RF best predicted LVO presence (AUC = 0.907 ± 0.856-0.957) while logistic regression best predicted MT candidacy (AUC = 0.930 ± 0.886-0.974). When compact models were evaluated, a 10-feature RF model best predicted LVO (AUC = 0.841 ± 0.778-0.904) and an 8-feature RF model best predicted MT candidacy (AUC = 0.862 ± 0.782-0.942). The compact RF models had sensitivity, specificity, negative predictive value and positive predictive value of 0.81, 0.87, 0.92, 0.72 for LVO and 0.87, 0.97, 0.97, 0.86 for MT, respectively. The 10-feature RF model was superior at predicting LVO to all previous stroke scales (AUC 0.944 vs 0.759-0.878) and the 8-feature RF model was superior at predicting MT (AUC 0.970 vs 0.746-0.834). CONCLUSION: Random forest machine learning models utilizing clinical and demographic variables predicts LVO presence and MT candidacy with a high degree of accuracy in an ischemic stroke cohort. Further validation of this strategy for triage of stroke patients requires prospective and external validation.


Assuntos
Isquemia Encefálica , AVC Isquêmico , Acidente Vascular Cerebral , Isquemia Encefálica/diagnóstico , Isquemia Encefálica/cirurgia , Humanos , Aprendizado de Máquina , Masculino , Estudos Prospectivos , Estudos Retrospectivos , Acidente Vascular Cerebral/diagnóstico , Acidente Vascular Cerebral/cirurgia , Trombectomia , Ativador de Plasminogênio Tecidual
6.
Neurocirugía (Soc. Luso-Esp. Neurocir.) ; 32(4): 199-202, jul.- ago. 2021. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-222732

RESUMO

Los quistes coloides son lesiones intracraneales benignas localizadas mayoritariamente en el III ventrículo en la región de los agujeros de Monro. La mayoría se presentan entre la tercera y cuartas décadas de la vida, y son poco frecuentes por debajo de los 10 años. Presentamos el caso de una niña de 2,5 años que presentaba un quiste coloide incidental que fue seguido de manera conservadora, observándose en los estudios de resonancia magnética una progresiva regresión en su tamaño. Realizamos una revisión de los 4 casos similares publicados con anterioridad (AU)


Colloid cyst are benign intracranial lesions located in the III ventricle in the region of the foramen of Monro. The majority present in the third and fourth decades of life and are rare under the age of ten. We report a case of an incidentally colloid cyst presented in a 2.5 -years-old girl who was managed conservatively; follow-up with MRI showed a progressive reduction in size. We review the four similar case previously reported (AU)


Assuntos
Humanos , Feminino , Pré-Escolar , Remissão Espontânea , Cistos Coloides/diagnóstico por imagem , Terceiro Ventrículo/diagnóstico por imagem , Imageamento por Ressonância Magnética
7.
Neurocirugía (Soc. Luso-Esp. Neurocir.) ; 32(2): 84-88, mar.- apr. 2021. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-222446

RESUMO

El neumoencéfalo a tensión es una complicación extremadamente rara en el uso de la ventilación a presión positiva en el neonato, cuyo diagnóstico requiere un alto grado de sospecha clínica. Presentamos el caso de un recién nacido prematuro, que recibió oxígeno a través de cánulas nasales de alto flujo debido a enfermedad de membrana hialina, propia de su prematuridad, y que desarrolló signos clínicos de hipertensión intracraneal. La ecografía transfontanelar y la TAC craneal pusieron de manifiesto un importante neumoencéfalo a tensión que fue evacuado a través de punción directa a través de la fontanela anterior (AU)


Tension pneumocephalus is an extremely rare complication of positive-pressure ventilation in neonates, the diagnosis of which requires a high degree of clinical suspicion. We present the case of a preterm newborn, who received high-flow nasal cannula oxygen therapy because of hyaline membrane disease, due to his prematurity, and developed clinical signs of intracranial hypertension. Transfontanellar ultrasound and cranial CT scan revealed significant tension pneumocephalus, which was evacuated with direct needle puncture through the anterior fontanelle (AU)


Assuntos
Humanos , Feminino , Recém-Nascido , Recém-Nascido Prematuro , Hipertensão Intracraniana/etiologia , Pneumocefalia/diagnóstico por imagem , Pneumocefalia/etiologia , Pressão Positiva Contínua nas Vias Aéreas/efeitos adversos , Tomografia Computadorizada por Raios X , Complicações Pós-Operatórias
8.
Complement Ther Med ; 58: 102710, 2021 May.
Artigo em Inglês | MEDLINE | ID: mdl-33727090

RESUMO

OBJECTIVE: Despite evidence that chronic stress, racism, and discrimination impact the well-being and the risk for cardiovascular disease (CVD) in Black women, there are few evidence-based interventions that improve well-being and reduce the risk for CVD in women of minority groups. The purpose of this pilot study was to evaluate the psychobehavioral and anti-inflammatory benefit of a race-based stress reduction program "Resilience, Stress, and Ethnicity (RiSE) for Black women at risk for CVD. METHODS: Black women were recruited from the Chicagoland community and randomized to either the 8-week RiSE intervention (n = 40) or control group (n = 34). Participants were assessed for coping strategies, psychological distress, and blood levels of TNF-alpha and high sensitivity C-reactive protein (hsCRP) at baseline and at 4 and 8 weeks after baseline. RESULTS: Participation in RiSE was associated with a more rapid decline in the use of avoidance coping (b = -0.3585, SE = 0.1705, p < .01). Reductions over time in TNF-alpha (b = -0.0163, SE = .0087, p = .08) and hsCRP (b= -0.4064, SE = 0.2270, p = .08) approached statistical significance. CONCLUSIONS: Findings provide preliminary evidence in Black women at risk for CVD that RiSE contributes to decreases in avoidance coping. Although preliminary, these results suggest RiSE to be an effective intervention to promote improved coping associated with racism and discrimination in minorities.


Assuntos
Doenças Cardiovasculares , Racismo , Adaptação Psicológica , Negro ou Afro-Americano , Doenças Cardiovasculares/prevenção & controle , Feminino , Humanos , Projetos Piloto , Estresse Psicológico/terapia
9.
Sci Adv ; 7(6)2021 02.
Artigo em Inglês | MEDLINE | ID: mdl-33547077

RESUMO

Despite numerous journalistic accounts, systematic quantitative evidence on economic conditions during the ongoing COVID-19 pandemic remains scarce for most low- and middle-income countries, partly due to limitations of official economic statistics in environments with large informal sectors and subsistence agriculture. We assemble evidence from over 30,000 respondents in 16 original household surveys from nine countries in Africa (Burkina Faso, Ghana, Kenya, Rwanda, Sierra Leone), Asia (Bangladesh, Nepal, Philippines), and Latin America (Colombia). We document declines in employment and income in all settings beginning March 2020. The share of households experiencing an income drop ranges from 8 to 87% (median, 68%). Household coping strategies and government assistance were insufficient to sustain precrisis living standards, resulting in widespread food insecurity and dire economic conditions even 3 months into the crisis. We discuss promising policy responses and speculate about the risk of persistent adverse effects, especially among children and other vulnerable groups.


Assuntos
COVID-19/economia , COVID-19/epidemiologia , Países em Desenvolvimento/economia , Emprego/tendências , Renda/tendências , Pandemias/economia , SARS-CoV-2 , Adulto , África/epidemiologia , Agricultura/economia , Ásia/epidemiologia , COVID-19/virologia , Criança , Colômbia/epidemiologia , Violência Doméstica , Recessão Econômica , Características da Família , Feminino , Insegurança Alimentar/economia , Programas Governamentais/economia , Humanos , Masculino , Estações do Ano , Inquéritos e Questionários
10.
Neurocirugia (Astur : Engl Ed) ; 32(2): 84-88, 2021.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-31784352

RESUMO

Tension pneumocephalus is an extremely rare complication of positive-pressure ventilation in neonates, the diagnosis of which requires a high degree of clinical suspicion. We present the case of a preterm newborn, who received high-flow nasal cannula oxygen therapy because of hyaline membrane disease, due to his prematurity, and developed clinical signs of intracranial hypertension. Transfontanellar ultrasound and cranial CT scan revealed significant tension pneumocephalus, which was evacuated with direct needle puncture through the anterior fontanelle.


Assuntos
Hipertensão Intracraniana , Pneumocefalia , Humanos , Recém-Nascido , Oxigênio , Pneumocefalia/diagnóstico por imagem , Pneumocefalia/etiologia , Pneumocefalia/terapia , Complicações Pós-Operatórias , Tomografia Computadorizada por Raios X
11.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-33054998

RESUMO

Colloid cyst are benign intracranial lesions located in the III ventricle in the region of the foramen of Monro. The majority present in the third and fourth decades of life and are rare under the age of ten. We report a case of an incidentally colloid cyst presented in a 2.5 -years-old girl who was managed conservatively; follow-up with MRI showed a progressive reduction in size. We review the four similar case previously reported.

12.
Asian J Urol ; 7(4): 345-350, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32995279

RESUMO

OBJECTIVE: Once chronic inflammatory renal disease (IRD) develops, it creates a severe peri-fibrotic process, which makes it a relative contraindication for minimally invasive surgery (MIS). Our objective is to show that laparoscopic nephrectomy (LN) is a surgical option in IRD with fewer complications and better outcomes. METHODS: Retrospective review of patients who underwent a modified-surgical laparoscopic transperitoneal nephrectomy was performed. Data search included all operated patients between May 2013 and May 2018 that had a pathology result with any renal inflammatory condition (xanthogranulomatous pyelonephritis, chronic nephritis, and renal tuberculosis). We describe intra-operative variables such as operative time, blood loss, conversion rate, postoperative complications and length of hospital stay. RESULTS: There were 51 patients who underwent laparoscopic nephrectomy with a confirmatory pathology report for IRD. We identified four (8%) major complications; three of them required transfusion and one conversion to open surgery. The mean operative time was 233±108 min. Mean estimated blood loss was 206±242 mL excluding the conversion cases and 281±423 mL including them. The mean length of hospital stay was 3.0±2.0 days. CONCLUSION: Laparoscopic nephrectomy for IRD can safely be done. It is a reproducible technique with low risks and complication rates. Our experience supports that releasing the kidney first and leaving the hilum for the end is a safe approach when vascular structures are embedded into a single block of inflammatory and scar tissue.

16.
urol. colomb. (Bogotá. En línea) ; 29(3): 136-140, 2020. tab, graf
Artigo em Inglês | LILACS, COLNAL | ID: biblio-1410593

RESUMO

Objectives Patients undergoing retropubic radical prostatectomy (RRP) may suffer from lower urinary tract symptoms (LUTS). We aim to characterize LUTS and to evaluate the correlation and agreement between uroflowmetry and the International Prostate Symptom Score (IPSS) in patients after RRP in two reference centers. Methods An observational multicenter prospective study was conducted between December 2015 and September 2016. Patients with at least 12-months of follow-up after RRP were included; these were evaluated with uroflowmetry and the IPSS. Results A total of 90 patients were included. The mean follow-up was of 54.6 months (standard deviation [SD] = 27.52), and the mean age was 65 (SD = 6.85) years old. The mean IPSS was 7.41 (SD = 6.29), with 33.3% (n = 54) of the patients with moderate symptoms and 6.7% (n = 6) with severe symptoms. A total of 50% (n = 45) of the patients had normal uroflowmetry. Patients with an abnormal/equivocal result in the uroflowmetry had a mean of 9.31 (SD = 7.03) points in the IPSS versus 5.51 (SD = 4.82) in patients with a normal uroflowmetry result (p < 0.01). The level of agreement between mild versus moderate-to-severe LUTS and normal uroflowmetry versus abnormal/equivocal was 61.1% (k = 0.22, p = 0.04). We found that a score ≥ 10 in the IPSS had a level of agreement of 65.6% (k = 0.31, p = 0.0004). Conclusions We consider that although the IPSS cannot replace uroflowmetry and vice versa, these tests are complementary and may be useful tools in the evaluation of patients with LUTS after RRP.


Objetivos Los pacientes en quienes se realiza prostatectomía radical retropúbica (PRR) pueden sufrir de síntomas del tracto urinario inferior (STUIs). El propósito es poder caracterizar STUI y correlacionarlos con la uroflujometría y la Escala Internacional de Síntomas Prostáticos (IPSS por sus siglas en inglés). Métodos Se realizó un estudio multicéntrico prospectivo entre Diciembre de 2015 y Septiembre de 2016. Se incluyeron todos los pacientes con un seguimiento mínimo de 12 meses después de la PRR. Estos fueron evaluados con uroflujometría e IPSS. Resultados Se incluyeron un total de 90 pacientes. El seguimiento promedio fue de 54,6 meses (desviación estándar [DE] = 27,52), la edad promedio fue de 65 años (DE 6,85). El promedio de la puntuación en la IPSS fue de 7,41 (DE = 6,29) con 33,3% de los pacientes con síntomas moderados y 6,7% con síntomas severos. El 50% de los pacientes tuvieron una uroflujometría normal. Los pacientes con resultado anormal o equívoco en la uroflujometría presentaron un promedio de 9,31 (DE = 7,03) en la puntuación de la IPSS, versus 5,51 (DE = 4,82) en pacientes con una uroflujometría normal (p < 0,01). El nivel de concordancia entre los STUIs leves y moderados/severos y uroflujometría normal versus anormal/equívoca fue de 61,1% (k = 0,22, p = 0,04). Se encontró que un puntaje ≥ 10 en la IPSS tiene un nivel de concordancia del 65,6% (k = 0.31, p = 0.0004). Conclusiones Se considera que aunque la IPSS no puede reemplazar la uroflujometría y viceversam, estas pruebas son complementarias, y son herramientas útiles en la evaluación de pacientes con STUIs después de la PRR.


Assuntos
Humanos , Masculino , Idoso , Prostatectomia , Neoplasias da Próstata , Sintomas do Trato Urinário Inferior , Qualidade de Vida , Sistema Urinário , Urodinâmica , Estudos Prospectivos
17.
urol. colomb. (Bogotá. En línea) ; 29(2): 91-95, 2020. ilus
Artigo em Inglês | LILACS, COLNAL | ID: biblio-1402767

RESUMO

Introduction Transitional cell carcinoma of the bladder (TCCB) is uncommon in the pediatric population, and its etiology, natural history and epigenetics remain poorly understood. We aim to describe six cases of TCCB in pediatric patients and discuss the state of the art in the management and follow-up of the patients with this uncommon early presentation. Methods The clinicopathological data of 6 patients with TCCB who underwent transurethral resection of bladder tumor (TURBT) were obtained from our institutional database. The patient data were collected retrospectively. A review of the literature was performed, and the most relevant and trending data were analyzed. Results A total of 6 patients (4 female, 2 male) were treated at our institution between 2004 and 2019. The mean age of the sample was 12 years, and the presenting symptoms were macroscopic hematuria (3 cases), suprapubic pain (2 cases), and 1 case was an incidental finding during pelvic ultrasonography. The long-term follow-up (median follow-up of 61 months) did not reveal recurrence. Conclusion Transitional cell carcinoma of the bladder rarely presents in the pediatric population. Genetic and epigenetic anomalies have been proposed as causes, as well as carcinogenic exposure. The reported cases tend to have a good prognosis, and most are non-invasive at the diagnosis. Follow-up protocols are still lacking, as well as molecular insights on tumor development and prognostic markers.


Introducción Carcinoma de células transicionales de vejiga (CCTV) es una patología rara en la población pediátrica, su etiología, historia natural y epigenetica son pobremente entendidos. El objetivo de este articulo es describir 6 casos de CCTV en pacientes pediátricos, discutir el estado del arte en el manejo y seguimiento de los pacientes. Métodos Los datos clinicopatologicos de 6 pacientes con CCTV sometidos a resección transuretral de tumor vesical (RTU-TV) se analizaron de nuestra base de datos institucional. Los datos fueron recolectados y analizados de manera retrospectiva. Se realizo una revisión de la literatura y solo los artículos mas relevantes fueron analizados. Resultados Un total de 6 pacientes (4 mujeres, 2 hombres) fueron tratados en nuestra institución entre el 2004 y el 2019. La media de edad fue 12 años y los síntomas mas frecuentes fueron hematuria macroscópica (3 casos), dolor suprapúbico (2 casos) y en un caso fue un hallazgo incidental durante una ultrasonografía pélvica. El seguimiento a largo plazo (mediana de seguimiento de 61 meses) no mostro recurrencia en ningún paciente. Conclusión CCTV se presenta infrecuentemente en la población pediátrica, Anomalías genéticas y epigeneticas han sido propuestas como causas predisponentes al igual que la exposición a carcinogénicos. Los casos reportados tienden a tener un buen pronostico y la gran mayoría son no musculo invasivos al momento del diagnostico. Protocolos de seguimiento no están claramente definidos igual que vías moleculares en la tumorogenésis y marcadores pronósticos


Assuntos
Humanos , Masculino , Feminino , Criança , Bexiga Urinária , Neoplasias da Bexiga Urinária , Carcinoma de Células de Transição , Ultrassonografia , Guias como Assunto , Assistência ao Convalescente , Epigenômica , Carcinogênese
18.
Neurocirugía (Soc. Luso-Esp. Neurocir.) ; 30(6): 288-293, nov.-dic. 2019. graf, tab
Artigo em Espanhol | IBECS | ID: ibc-186958

RESUMO

Introducción: La espasticidad representa un problema médico cuya incidencia está aumentando debido a enfermedades como parálisis cerebral, ictus, esclerosis múltiple, traumatismos o encefalopatías, afectando tanto a adultos como a niños. Los tratamientos incluyen rehabilitación, farmacoterapia y cirugía, entre las cuales destacamos las bombas de baclofeno intratecal. Material y métodos: Seleccionamos a los pacientes portadores de bomba de baclofeno intratecal implantada en el Hospital Clínico de Santiago de Compostela entre 2005-2018 y analizamos retrospectivamente los resultados mediante escalas de valoración de espasticidad, como la de Ashworth, así como las complicaciones observadas. Resultados: Se implantaron bombas de baclofeno a 17 pacientes, obteniendo una mejoría de 2 puntos en la escala de Ashworth en el 88,2% y de 1 punto en la escala de Penn en el 94%. Se observaron complicaciones en 3 pacientes. Conclusiones: El tratamiento con baclofeno intratecal es una técnica sencilla con resultados muy positivos para mejorar la calidad de vida de pacientes con espasticidad


Introduction: Spasticity represents a medical problem whose incidence is increasing during the last years due to pathologies such as cerebral palsy, stroke, multiple sclerosis, trauma or encephalopathy, affecting both adults and children. The treatments include rehabilitation, pharmacotherapy and surgery, among which we highlight intrathecal baclofen infusion devices. Material and methods: Intrathecal baclofen devices implanted patients in Clinical Hospital of Santiago de Compostela from 2005 to 2018 were selected for retrospective analysis using assessment of spasticity scales, such as Ashworth scale. Complications are described. Results: Surgery was performed in 17 patients for baclofen pump implant, achieving an improvement of 2 points on the Ashworth Scale in 88,2% of the patients and of 1 point on the Penn Scale in 94%. Complications were seen in 3 patients. Conclusions: Intrathecal baclofen is a simple technique with good results for improving the quality of life of patients with spasticity


Assuntos
Humanos , Masculino , Feminino , Adulto , Baclofeno/administração & dosagem , Espasticidade Muscular/tratamento farmacológico , Estudos Retrospectivos , Espasticidade Muscular/complicações , Esclerose Múltipla/etiologia , Neurofisiologia
20.
Neurocirugia (Astur : Engl Ed) ; 30(6): 288-293, 2019.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-31208871

RESUMO

INTRODUCTION: Spasticity represents a medical problem whose incidence is increasing during the last years due to pathologies such as cerebral palsy, stroke, multiple sclerosis, trauma or encephalopathy, affecting both adults and children. The treatments include rehabilitation, pharmacotherapy and surgery, among which we highlight intrathecal baclofen infusion devices. MATERIAL AND METHODS: Intrathecal baclofen devices implanted patients in Clinical Hospital of Santiago de Compostela from 2005 to 2018 were selected for retrospective analysis using assessment of spasticity scales, such as Ashworth scale. Complications are described. RESULTS: Surgery was performed in 17 patients for baclofen pump implant, achieving an improvement of 2 points on the Ashworth Scale in 88,2% of the patients and of 1 point on the Penn Scale in 94%. Complications were seen in 3 patients. CONCLUSIONS: Intrathecal baclofen is a simple technique with good results for improving the quality of life of patients with spasticity.


Assuntos
Baclofeno/administração & dosagem , Bombas de Infusão Implantáveis , Relaxantes Musculares Centrais/administração & dosagem , Espasticidade Muscular/tratamento farmacológico , Adolescente , Adulto , Idoso , Criança , Feminino , Humanos , Bombas de Infusão Implantáveis/efeitos adversos , Injeções Espinhais , Masculino , Pessoa de Meia-Idade , Espasticidade Muscular/etiologia , Estudos Retrospectivos , Adulto Jovem
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