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1.
Med Phys ; 30(10): 2849-54, 2003 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-14596320

RESUMO

Dose to the total body from induced radiation resulting from primary exposure to radiotherapeutic beams is not detailed in routine treatment planning though this information is potentially important for better estimates of health risks including secondary cancers. This information can also allow better management of patient treatment logistics, suggesting better timing, sequencing, and conduct of treatment. Monte Carlo simulations capable of taking into account all interactions contributing to the dose to the total body, including neutron scattering and induced radioactivity, provide the most versatile and accurate tool for investigating these effects. MCNPX code version 2.2.6 with full IAEA library of photoneutron cross sections is particularly suited to trace not only photoneutrons but also protons and heavy ion particles that result from photoneutron interactions. Specifically, the MCNPX code is applied here to the problem of dose calculations in traditional (non-IMRT) photon beam therapy. Points of calculation are located in the head, where the primary irradiation has been directed, but also in the superior portion of the torso of the ORNL Mathematical Human Phantom. We calculated dose contributions from neutrons, protons, deutrons, tritons and He-3 that are produced at the time of photoneutron interactions in the body and that would not have been accounted for by conventional radiation oncology dosimetry.


Assuntos
Neoplasias Induzidas por Radiação/etiologia , Neoplasias/radioterapia , Nêutrons/uso terapêutico , Humanos , Íons , Masculino , Método de Monte Carlo , Nêutrons/efeitos adversos , Imagens de Fantasmas , Fótons , Radiometria , Dosagem Radioterapêutica , Planejamento da Radioterapia Assistida por Computador , Espalhamento de Radiação
2.
Med Phys ; 27(3): 568-79, 2000 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-10757608

RESUMO

Monte Carlo simulations of digital images of the contrast detail phantom and the ACR phantom are presented for two different x-ray digital mammography modalities: a synchrotron mammography system and a next-generation scanning slot clinical system. A combination of variance reduction methods made it possible to simulate accurate images using real pixel dimensions within reasonable computation times. The complete method of image simulation, including a simple detector response model, a simple noise model, and the incorporation of system effects (MTF), is presented. The simulated images of the phantoms show good agreement with images measured on the two systems.


Assuntos
Mamografia/métodos , Método de Monte Carlo , Algoritmos , Mamografia/instrumentação , Imagens de Fantasmas , Interpretação de Imagem Radiográfica Assistida por Computador/métodos , Espalhamento de Radiação , Software , Síncrotrons
3.
Phys Med Biol ; 43(9): 2431-52, 1998 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-9755937

RESUMO

Photon scattering angular distributions from various animal tissues were measured at two energies of a monochromatic synchrotron x-ray beam. Two plastics and human breast tissue were also measured. From these two measurements, the molecular coherent scattering form factor of each material was extracted. A new data analysis technique that uses Monte Carlo based corrections for air scattering, incoherent scattering and multiple scattering was used. The form factors of the 16 materials are presented in tabular form, suitable for use in computer calculations.


Assuntos
Mama/anatomia & histologia , Mamografia/métodos , Animais , Fenômenos Biofísicos , Biofísica , Bovinos , Simulação por Computador , Feminino , Humanos , Mamografia/estatística & dados numéricos , Modelos Teóricos , Método de Monte Carlo , Especificidade de Órgãos , Imagens de Fantasmas , Fótons , Plásticos , Espalhamento de Radiação , Suínos
6.
Bol. Oficina Sanit. Panam ; 93(3): 233-9, sept. 1982.
Artigo em Espanhol | LILACS | ID: lil-7453

RESUMO

Este estudio es el primero que compara la incidencia de parasitos intestinales en los habitantes de las regiones amazonica, andina y costera de Ecuador, y en el que un mismo investigador, con tecnicas identicas, examino a 1568 personas de 12 comunidades con ambientes diferentes


Assuntos
Enteropatias Parasitárias , Cestoides , Eucariotos , Nematoides
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