[Human dirofilariasis in Corsica: a new local case. Review of reported cases]. / Dirofilariose humaine en Corse: un nouveau cas autochtone. Révision des cas déja publiés.

A case of human dirofilariasis with Dirofilaria (Nochtiella) repens, located in a subcutaneous nodule of the arch of the foot is reported in a 64-year-old man living in the surroundings of Porto Vecchio in Corsica. The histological examination of this nodule has revealed a gravid female nematode, dead some weeks or months before its surgical excision. It is the second case of human dirofilariasis observed in a patient living on the island. The authors are surprised by the number of patients reported in medical literature (10 altogether) as having contracted the infection probably during a short stay in Corsica. This paper seeks to collect the fragmented available data on the existence in Corsica of nematodes in dogs and its possible vectors.

[Management of asymptomatic small tumor of the kidney of incidental discovery]. / Conduite à tenir devant une petite tumeur du rein asymptomatique de découverte fortuite.

OBJECTIVE: The incidental discovery of renal tumours is increasingly frequent. All small renal tumours are not inevitably cancers. The objective of our study was to compare radiological and histological data and to establish a diagnostic and therapeutic approach to the incidental discovery of a small renal tumour. MATERIAL AND METHODS: Retrospective study of 22 incidentally discovered asymptomatic renal tumours, with a long axis of less than 5 cm on the pathology specimen. RESULTS: The tumour was discovered on ultrasound in 68% of cases. All patients were operated, allowing histological examination of the operative specimen, revealing 14 cancers, 4 angiomyolipomas, 2 adenomas and 2 haemorrhagic cysts (with thick contents). Ultrasound demonstrated a hypoechoic tumour in 13 cases, 11 of which were cancers, and a hyperechoic tumour in the other 7 cases, corresponding to 4 angiomyolipomas, 2 cancers, and 1 adenoma. Computed tomography showed a heterogeneous tumour in 12 cases, corresponding to a cancer in all but one case. The tumour was homogeneous in the other 10 cases, including 4 cancers. Arteriography showed a hypervascular tumour in 3 cases, all cancers, and a hypovascular tumour in 7 cases: 2 cancers, 2 adenomas, 2 very small angiomyolipomas and 1 haemorrhagic cyst. CONCLUSION: Despite the development of medical imaging, further progress is required to resolve the diagnostic problems raised by certain incidentally discovered asymptomatic renal tumours, particularly tumours with a homogeneous appearance on CT scan and a hypovascular appearance on arteriography.

[Prostatic localization revealing an acute myeloid leukemia. Apropos of a case]. / Localisation prostatique révélatrice d'une leucémie aiguë myéloïde. A propos d'un cas.

The authors report an original case of acute myeloid leukaemia (AML) presenting in the form of acute urinary retention, confirmed by prostatic biopsy, with complete absence of any non-urological clinical features. Prostatic sites of leukaemia are frequent and classically reported, but often occur during the course of known leukaemia, and are rarely symptomatic, justifying biopsies in the presence of any prostatic symptoms. Immunolabelling represents the key to the diagnosis in the presence of undifferentiated cells demonstrated on prostatic biopsies. The outcome was fatal in this case, despite early chemotherapy. The clinical features, clinical course and therapeutic aspects of prostatic leukaemia are discussed.

[Neurofibroma of the recurrent nerve: apropos of a case]. / Neurofibrome du nerf recurrent: à propos d'un cas.

A case of solitary benign neurofibroma of the recurrent laryngeal nerve is presented. The preoperative diagnosis was in favour of a thyroid cancer. The discovery of this benign tumour leads to discuss the malignancy criteria of a cold nodule. The recurrential paralysis is an evidence of malignancy in only about 80% of cases. The surgical operation is the best treatment because it allows the histology that asserts the benignancy of the lesion. The review of the literature confirms the exceptional nature of this tumour. The respective histology of neurofibromas is finally briefly recalled.

[Neuroendocrine tumors of the mammary gland. Current evaluation apropos of a case]. / Les tumeurs neuroendocrines de la glande mammaire. Bilan actuel à propos d'un cas.

The authors report a case of infiltrating non-mucinous neuroendocrine breast tumor of both nesidioid and carcinoid type, exclusively composed of argyrophil cells and showing estrogen receptors. By comparing it to those published in literature, they conclude that there are two types of breast tumors with argyrophil cells: one very rare, exclusively composed of neuroendocrine cells, which may present all of the morphological, functional, evolutive aspects and particularly the carcinoid pattern of diffuse endocrine system tumors; the other is more common, composite, reminiscent according to the abundance of their neuroendocrine components, either of the features of diffuse endocrine system tumors, or of those of conventional adenocarcinomas. Their findings help to explain that the combined hormonoreceptive and hormonosecreting nature of these tumors is the particular property of their neuroendocrine cells comparable to that of the pituitary gland. In the composite tumors, these cells are associated in symbiosis with the epithelial glandular cells which are of ectodermal origin. Such an association, also observed in other parts of the body, is not fortuitous but functional and thus could contra-indicate antiestrogen hormonetherapy.