RESUMO
A case of cutaneous zygomycosis caused by Absidia corymbifera in a leukemic patient submitted to chemotherapy is reported. The lesion was located on the little finger of the right hand and probably resulted from a latent osteomyelitis. It progressed to form extensive necrotic area. No systemic infection was detected and the lesion did not appear to be associated with any trauma.
Assuntos
Dermatomicoses/complicações , Leucemia Mieloide Aguda/complicações , Mucormicose/complicações , Adulto , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Dermatomicoses/microbiologia , Dermatomicoses/patologia , Humanos , Leucemia Mieloide Aguda/tratamento farmacológico , Masculino , Mucorales/isolamento & purificação , Mucormicose/microbiologia , Mucormicose/patologia , Osteomielite/complicações , Osteomielite/diagnóstico por imagem , Osteomielite/microbiologia , RadiografiaRESUMO
Isolated Factor V deficiency is a very rare inherited coagulopathy. A genealogy of Brazilian Caucasians, where this disorder occurs, is reported. In this family, which was located because 2 affected individuals having the same surname were found by chance, the genealogical and laboratory data suggest an autosomal recessive pattern of inheritance. Nevertheless, the existence of deceased individuals who were reported as symptomatic seems to imply that some heterozygotes may present occasional bleeding episodes.
