EVALUATION OF INTRAOPERATIVE PAIN OCCURRENCE AND NEED FOR SUPPLEMENTAL ANESTHESIA DURING EMERGENCY DENTAL CARE

Aims: This study aimed to evaluate the intraoperative pain (IOP) occurrence in situations of symptomatic irreversible pulpitis (SIP) and symptomatic apical periodontitis (SAP). Materials and Methods: Patients who sought emergency care presenting a diagnosis of SIP or SAP were included. IOP was measured with a Visual Analogue Scale (VAS) after five minutes of local anesthesia, during access to the pulp chamber, root canal exploration and at the end of procedures. In cases where pain was reported during treatment, supplementary anesthesia was performed. Pain scores were recorded and analyzed using a generalized estimating equation model with posthoc comparisons. Results: 56 patients were included. 35 had a diagnosis of SIP; and 21 a diagnosis of SAP. Mean preoperative pain scores for SAP and SIP were 6.69 (±1.54) and 6.39 (±1.48), respectively (p>0.05). In patients with SIP, significant differences were observed between: preoperative scores and other time points; scores after five minutes of local anesthesia and other time points; scores during pulp chamber access and at the end of procedures; and scores during root canal exploration and at the end of procedures (p<0.05). In patients with SAP, significant differences were observed between preoperative pain scores with all other time points (p<0.05). Chi-square test indicated an association between diagnosis and the need for supplementary anesthesia (p<0.05). Conclusions: In conclusion, there is a strong relationship between reduction of moderate/severe pain after application of local anesthesia. The need for supplemental anesthesia is significantly associated to the diagnosis of symptomatic irreversible pulpitis.

ARE CALCIUM SILICATE SEALERS LESS CYTOTOXIC AND GENOTOXIC THAN EPOXY RESIN SEALERS? A SYSTEMATIC REVIEW OF IN VITRO STUDIES

Aims: This systematic review aimed to evaluate whether calcium silicate-based sealers are less cytotoxicity and genotoxicity than epoxy resin-based sealers. Materials and Methods: Systematic searches were conducted for studies published up to September 27th, 2022, without restriction for language or year of publication, in the following databases: MEDLINE/PubMed, Scopus, Web of Science and Grey Literature Report. Only in vitrostudies that evaluated the cytotoxicity or genotoxicity of calcium silicate and epoxy resin-based sealers were included. The quality assessment was performed. Results: After duplicate removal and eligibility criteria assessment, a total of thirty-four studies were included. Twenty-eight studies had a low risk of bias, and six studies had amoderate risk of bias. In general, calcium silicate-based sealers had a lower cytotoxic and genotoxic potential than epoxy-resin based sealers.Conclusions: Based on the findings from in vitrostudies, calcium silicate-based sealers are less cytotoxic andgenotoxic than epoxy resin-based sealers

Preheated restorative composite resin for luting ceramic laminate veneers: An optimized technique report.

Resin cements are traditionally used to lute ceramic laminate veneers due to their lower viscosity, which facilitates a fast restoration seating. However, resin cements have lower mechanical properties compared to restorative composite resins. Thus, restorative composite resin is an alternative luting agent with lower marginal degradation as a potential advantage for clinical longevity. This article presents an application of preheated restorative composite resin for adhesive luting of laminate veneers with a predictable clinical technique for seating and marginal quality. By addressing important factors that influence film thickness, the predictable presented workflow should overcome this major concern when luting with restorative composite resin, therefore enabling the benefits of using a restorative material with better mechanical properties without the drawback of higher film thickness. Considering the clinical evidence that the adhesive interface between the dental substrate and restoration is the weak link of adhesive indirect restorations, bonding the restoration with preheated restorative composite resins (PRCR) may provide an interface filled with a restorative resin material, presenting optimized mechanical properties. Key words:Resin cements, ceramic laminate veneers.

The Influence on Fracture Resistance of Different Composite Resins and Prefabricated Posts to Restore Endodontically Treated Teeth.

Recent formulations of resin-based composites have incorporated different combinations of materials. However, the mechanical and bonding behavior of these materials with intraradicular posts are unclear. This study aimed to evaluate the effect of light-cure and dual-cure resin composite posts on the fracture resistance of endodontically-treated teeth. Materials and Methods: Ninety extracted human upper canines were selected and randomly divided into nine groups (n=10): (G1) endodontically treated teeth without endodontic posts; (G2) glass-fiber post cemented with glass-ionomer cement; (G3) endodontic post by dual-cure composite resin (Rebilda DC); (G4) endodontic post by dual-cure composite resin (Cosmecore); (G5) endodontic post by dual-cure composite resin (Bis-Core); (G6) endodontic post by light-cure composite resin; (G7) glass-fiber post customized with flowable composite resin; (G8) glass-fiber post cemented with light-cure composite resin; (G9) glass-fiber post cemented with self-adhesive resin cement. After the post insertion, all specimens were subjected to mechanical (250,000 cycles) and thermocycling (6000 cycles, 5 °C/55 °C) and immediate loading at 45 degrees in a universal testing machine until fracture. The data were analyzed by one-way ANOVA and multiple comparisons using the Fisher LSD Method (p < 0 05). Results: The mean failure loads (±SD) for the groups ranged from 100.7 ± 22.6 N to 221.9 ± 48.9 N. The G1 group (without endodontic posts) had a higher fracture strength than all experimental groups (p < 0.001). Conclusions: Within the limitations, the light- and dual-cure post technique did not present lower fracture resistance values as compared to the conventional glass-fiber post.

Symptoms of post-traumatic stress disorder and affects in healthcare workers during the COVID-19 pandemic / Sintomas de transtorno de estresse pós-traumático e afetos em profissionais da saúde durante a pandemia da COVID-19

Objective: This study aimed to evaluate symptoms of post-traumatic stress disorder and affects in health professionals during the COVID-19 pandemic. Method: Three hundred and seventy-four health professionals, among which 235 were front-line and 139 non-front-line workers, answered an online questionnaire consisting of socio-demographic data, identification of past mental disorders, personal experience facing the pandemic, the Impact of Event Scale, and the Positive and Negative Affect Schedule. The sample consisted mainly of physicians and nursing staff aged between 30 and 49 years. Results: The results demonstrate high scores of symptoms related to post-traumatic stress disorder, with greater expressiveness among front-line professionals, especially in the nursing staff, and a strong correlation of these results with negative affects. Conclusion: Psychological assistance and interventions directed to health professionals are urgent to mitigate the impacts caused by the COVID-19 pandemic.

Objetivo: Este estudo objetivou avaliar sintomas de transtorno de estresse pós-traumático e afetos em profissionais de saúde durante a pandemia da COVID-19. Método: Trezentos e setenta e quatro profissionais da área da saúde, dentre os quais 235 profissionais que estavam atuando na linha de frente e 139 que não estavam na linha de frente, responderam a um questionário online composto por dados sociodemográficos, identificação de transtornos mentais pregressos, experiência pessoal frente à pandemia e Escala do Impacto do Evento e Escala de Afetos Positivos e Afetos Negativos. A amostra foi composta majoritariamente de médicos e funcionários da equipe de enfermagem com idades entre 30 e 49 anos. Resultados: Os resultados demonstram altas pontuações de sintomas relativos ao transtorno de estresse pós-traumático, com maior expressividade nos profissionais da linha de frente, principalmente na equipe de enfermagem, e forte correlação desses resultados com afetos negativos. Conclusão: O atendimento e intervenções psicológicas direcionadas aos profissionais de saúde são urgentes para mitigar os impactos causados pela pandemia da COVID-19.

Estresse, coping e estados afetivos em profissionais da saúde durante a pandemia / Distress, coping and affective statesin healthcare workers durig the COVID-19 pandemic / Estrés, afrontamiento y estados afectivos em profissionales de la salud durante la pandemia de COVID-19

A pandemia da COVID-19 configurou um período de crise mundial com impactos na saúde mental de toda a população, notadamente dos profissionais de saúde da linha de frente. Objetivou-se rastrear a presença de sintomas de Transtorno de Estresse Pós-Traumático em profissionais de saúde da linha de frente e verificar sua associação com estratégias de coping e estados afetivos durante a pandemia da COVID-19 no Brasil. Realizou-se um estudo longitudinal on-line com 51 profissionais da saúde da linha de frente residentes nas cinco regiões do Brasil que responderam aos instrumentos: Escala do Impacto do Evento, Escala de Afetos Positivos e Afetos Negativos, Escala de Coping Ocupacional e questionário sobre a experiência pessoal frente à pandemia. Por meio de análises de comparação de proporções e médias, bem como análise de correlações, verificou-se alto índice de sintomas relacionados ao Transtorno de Estresse Pós-Traumático nos três momentos de coleta com correlações significativas com afetos negativos, mas não com estratégias de coping. Destaca-se o risco aumentado para o desenvolvimento ou agravo de transtornos mentais nesses profissionais, particularmente quadros de estresse pós-traumático e dificuldades de regulação emocional, que exigem ações urgentes de cuidado psicológico (AU).

The COVID-19 pandemic forgeda period of global crisis with impacts on the mental health of the entire population, notably frontline health professionals.The study aimed to track the presence of Post-Traumatic Stress Disorder symptoms in frontline healthcare workers and verify its association with coping strategies and affective states during the COVID-19 pandemic in Brazil. A longitudinal onlinestudy was carried out with 51 frontline healthcare professionalsfrom the fiveregions of Brazilwho responded to the following instruments: Impact of Event Scale, Positive Affect and Negative Affect Scale, Occupational Coping Scale, and questionnaire about personal experience during the pandemic. Comparison of proportions and means, as well as correlationanalysis,revealeda high rate of symptoms related to Post-Traumatic Stress Disorder in the three point of data collection, with significant correlations with negative affects, but not with coping strategies. The increased risk for the development or worsening of mental disorders in these professionals is highlighted, particularly post-traumatic stress and emotional regulation difficulties, which require urgent psychological care actions (AU).

La pandemia de COVID-19 estableció un período de crisis global con impactos en la salud mental de toda la población, en particular de los profesionales de la salud de primera línea. El objetivo fue rastrear la presencia de síntomas de Trastorno de Estrés Postraumático en profesionales de salud de primera línea y verificar su asociación con estrategias de afrontamiento y estados afectivos durante la pandemia de COVID-19 en Brasil. Se realizó un estudio longitudinal onlinecon 51 profesionales de salud de primera línea residentes de las cincoregiones de Brasil que respondieron los siguientes instrumentos: Escala de Impacto de Evento, Escala de Afectos Positivos y Negativos, Escala de Afrontamiento Ocupacional y cuestionario sobre experiencia personal frente ala pandemia.Los análisisde comparación de proporciones y medias, así como análisis de correlaciones, mostró una alta tasa de síntomas relacionados con el Trastorno de Estrés Postraumático en los tres momentos de recolección de datos, con correlaciones significativas con los afectos negativos, pero no con las estrategias de afrontamiento. Se destaca el mayor riesgo para el desarrollo o empeoramiento de trastornos mentales en estos profesionales, en particular el estrés postraumático y las dificultades (AU).

Effect of Curing Modes on the Mechanical Properties of Commercial Dental Resin-Based Composites: Comparison between Different LEDs and Microwave Units.

Resin-based composites (RBCs) have transformed restorative dentistry and its procedures. However, the characteristics of RBCs have been modified over the years to enhance the physical and chemical properties of the materials. This context raises the need for studies that evaluate whether the properties of the RBCs that are commercially available are clinically adequate with different curing modes. This study aimed to evaluate the mechanical behavior of commercial RBCs after undergoing different curing modes. Twenty-three RBCs of different classes were evaluated. For curing the specimens, a microwave (BMS45, Brastemp) (for 3 min at 450 W) and three LED units were used: an Emitter A Fit (Schuster (second generation)) (light-curing for 15 s with an irradiance of 1250 mW/cm2), VALO (Ultradent (third generation)) (light-curing for 15 s with an irradiance of 1100 mW/cm2), and Emitter Now Duo (Schuster (second generation)) (light-curing for 15 s with an irradiance of 1100 mW/cm2). A total of 670 RBC specimens of 8 mm in diameter and 1 mm in depth were obtained. Afterward, a biaxial flexure strength test was performed until the failure of the specimens, using a universal testing machine set at a speed of 0.5 mm/min. The same specimens were subjected to infrared spectroscopy for evaluating the degree of conversion. Tukey's test was used for multiple comparisons at a significance level of 5%. The light-curing mode did not affect the flexure strength of the RBCs (p > 0.05), but the type and shade of RBCs did so (p < 0.05). In conclusion, the type of RBC directly interferes with the mechanical behavior of the material. However, the curing modes within the same RBC did not change the mechanical properties.

Effect of ultrasonic activation of the adhesive system on dentin tubule penetration and the pushout bond strength of fiber posts.

STATEMENT OF PROBLEM: Whether ultrasonic activation of the adhesive system improves dentin tubule penetration and the bond strength of fiber posts to root dentin is unclear. PURPOSE: The purpose of this in vitro study was to evaluate the effect of ultrasonic activation of 2 adhesive systems (etch-and-rinse and self-etch) and 1 glass ionomer cement on the dentin tubule penetration and pushout bond strength of fiber posts to root dentin. MATERIAL AND METHODS: Sixty maxillary central incisors were endodontically treated and divided into 6 groups (n=10) as per the post cementation strategy: etch-and-rinse, etch-and-rinse and ultrasonic, self-etch, self-etch and ultrasonic, glass ionomer cement, and glass ionomer cement and ultrasonic. The primers, the adhesives, and the glass ionomer cement were activated for 20 seconds each, and the fiber posts were cemented with a resin cement. Dentin tubule penetration was evaluated by confocal laser scanning microscopy and the pushout bond strength measured at 3 post locations: cervical, middle, and apical. The failure patterns were also described after pushout testing. RESULTS: Self-etch and ultrasonic showed higher dentin tubule penetration than the other cementation strategies (P<.05) and improved the bond strength values (P<.05), which were higher than etch-and-rinse and ultrasonic and glass ionomer cement and ultrasonic (P<.05). Adhesive failures at the cement and dentin interface were predominant in the etch-and-rinse, self-etch, and self-etch and ultrasonic groups. CONCLUSIONS: Ultrasonic activation improved the dentin tubule penetration of a self-etch adhesive system. The bond strength of fiber posts cemented with a self-etch adhesive system and a resin cement was improved after ultrasonic activation.

Impact of Nonsurgical Treatment of Asymptomatic Apical Periodontitis on the Oral Health-related Quality of Life: A Prospective Study.

Introduction: The aim of this study was to evaluate the impact of nonsurgical root canal treatment (nRCT) and the healing of asymptomatic apical periodontitis (AAP) on the oral health-related quality of life (OHRQoL) in a Brazilian population. Materials and Methods: This prospective longitudinal observational study included 56 adults, in which 84 teeth with asymptomatic apical periodontitis underwent nonsurgical root canal treatment. Socio-demographic and medical data were collected; the primary outcome oral health-related quality of life was measured by the short form of the Oral Health Impact Profile (OHIP-14). Statistical analysis was carried out by Mann-Whitney U-test, and changes in the oral health-related quality of life scores post-treatment were estimated by Student t-test. Results: The mean age was 51.0±15.2 years, with 53.5% of females. Overall, nRCT significantly improved the OHRQoL (P<0.001, effect size=0.76). Gender (female) was associated with a higher OHRQoL after nRCT (P<0.05). OHIP-14 showed a significant reduction six months after root canal treatment compared to baseline scores. Conclusion: Present findings revealed that nonsurgical root canal treatment improved the oral health-related quality of life in patients with asymptomatic apical periodontitis.

Spectrophotometric analysis of dental bleaching after bonding and debonding of orthodontic brackets.

INTRODUCTION: The aim of this study was to evaluate the bleaching effect after aging simulation in teeth submitted to bonding and debonding of orthodontic brackets. MATERIALS AND METHODS: For this study, 90 human premolars were selected, and randomly divided into 6 groups: control, bleaching, and other 4 groups submitted to bleaching after bonding and debonding brackets using different methods. Color measurement of sample through the CIE L*a*b* system was performed in three moments: T1 - after brackets debonding, T2 - after staining cycling, and T3 - after bleaching. For evaluation of results among the components L*, a* and b*, the two criteria analysis of variance and the multiple comparison Tukey test (p < 0.05) were used. RESULTS: Statistically significant difference was observed among the groups submitted to brackets bonding and debonding through self-conditioning adhesive system and tungsten drill, also the control and bleaching groups between the moments T1 e T2. CONCLUSION: Bonding and debonding brackets methods tested in this study showed influence on the sample color change, and after the tooth bleaching process, only the group without brackets previous bonding achieved the color value presented before the staining and aging of samples in the brackets absence.

Programa com jogos de raciocínio para adolescentes em situação de dependência de substâncias psicoativas / A thinking games program for adolescents in a situation of psychoactive-substance dependence / Programa con juegos de pensamiento para adolescentes en situación de dependencia a sustancias psicoactivas

OBJETIVO: verificar impactos da aplicação de um programa com uso de jogos de raciocínio embasado na metodologia Mind Lab nas funções executivas atenção, flexibilidade e planejamento em adolescentes em situação de dependência de substâncias psicoativas. MÉTODO: estudo quantitativo quase-experimental com aplicação de instrumentos de avaliação neuropsicológica pré e pós-intervenção. Participaram 35 adolescentes com idades entre 12 e 17 anos internados em um Centro de Atenção Integrada à Saúde Mental na cidade de São Paulo. RESULTADOS: evidenciou-se melhora na atenção após a aplicação do programa com jogos. Quanto às funções planejamento e flexibilidade, foram observadas melhoras, porém estas não foram significativas. CONCLUSÃO: foi possível verificar a importância da utilização de jogos de raciocínio como recurso lúdico no tratamento de adolescentes em condição de dependência de substâncias psicoativas, possibilitando a construção de estratégias que auxiliem no processo de recuperação e reabilitação.

OBJECTIVE: to analyze the impacts of the application of a program using thinking games based on the Mind Lab methodology on the executive functions: attention, flexibility and planning in adolescents in a situation of psychoactive-substance dependence. METHOD: quasi-experimental quantitative study with the application of neuropsychological assessment tools before and after intervention. Thirty-five adolescents aged 12 to 17 years old, admitted to an Integrated Mental Health Care Center in the city of São Paulo, participated in this study. RESULTS: there was evidence of attention improvement after application of the games program. Regarding the planning and flexibility functions, improvements were observed, but they were not significant. CONCLUSION: it was possible to observe the importance of using thinking games as a playful resource in the treatment of substance-dependent adolescents, thus enabling the construction of strategies that assist in their recovery and rehabilitation process.

OBJETIVO: verificar impactos de la aplicación de un programa utilizando juegos de pensamiento basados en la metodología Mind Lab sobre las funciones ejecutivas de atención, flexibilidad y planificación en adolescentes en situación de dependencia a sustancias psicoactivas. MÉTODO: estudio cuantitativo cuasiexperimental con aplicación de instrumentos de evaluación neuropsicológica antes y después de la intervención. Treinta y cinco adolescentes de 12 a 17 años, ingresados en un Centro Integrado de Atención de Salud Mental en la ciudad de São Paulo, participaron en este estudio. RESULTADOS: hubo evidencia de mejora en la atención después de la aplicación del programa con juegos. Con respecto a las funciones de planificación y flexibilidad, se observaron mejoras, pero estas no fueron significativas. CONCLUSIÓN: fue posible verificar la importancia del uso de juegos de pensamiento como recurso lúdico en el tratamiento de adolescentes en condición de dependencia de sustancias psicoactivas, permitiendo la construcción de estrategias que ayuden en el proceso de recuperación y rehabilitación.

Analysis of microleakage and marginal gap presented by new polymeric systems in class V restorations: An in vitro study.

OBJECTIVE: Evaluating the contraction of polymerization effect of silorane-based composite on dental interface in enamel. MATERIALS AND METHODS: Eighty class V cavities were confectioned in forty extracted molar teeth and restored with different combinations of resinous-based and bond system. They were divided into the following groups: (G1) three-step etch-and-rinse adhesive system and methacrylate-based resin, (G2) two-step etch-and-rinse adhesive system and methacrylate-based resin, (G3) Filtek P-90 self-conditioning adhesive system and methacrylate-based resin, (G4) Adper SE Plus self-conditioning adhesive system and methacrylate-based resin, (G5) three-step etch-and-rinse adhesive system and silorane-based resin, (G6) two-step etch-and-rinse adhesive system and silorane-based resin, (G7) Filtek P-90 self-conditioning adhesive system and silorane-based resin, (G8) Adper SE Plus self-conditioning adhesive system and silorane-based resin. RESULTS: Group 7 showed lower marginal leakage when compared with all other groups (p = 0.001). CONCLUSIONS: The results allows suggesting that silorane-based resinous system is adequate to promote more satisfactory marginal sealing than any other combination, since the system is combined with its own bond system.

Push-out bond strength of fiberglass posts cemented with adhesive and self-adhesive resin cements according to the root canal surface.

Evaluating the bond strength of fiberglass posts cemented with different resin cements. MATERIALS AND METHODS: Seventy freshly extracted roots of healthy human canines were endodontically treated and prepared to receive fiberglass posts. The roots were randomly divided into seven groups: (G1) RelyX ARC, (G2) Enforce, (G3) BisCem, (G4) Duo-Link, (G5) Cement Post, (G6) Variolink II, and (G7) RelyX U200. After post cementation, the specimens were sectioned perpendicularly to the root axis using a high-speed diamond disc, totaling 340 specimens. The strength values obtained in the push-out test were submitted to two-factor ANOVA and Tukey test (p = 0.05). RESULTS: The root thirds (p = 0.001) and the type of cement (p = 0.001) influenced the bond strength values. The relation between these two factors was also significant (p = 0.011). CONCLUSIONS: The bond strength of self-adhesive resin cements was significantly higher as compared to other cements. Besides the cervical third in roots cemented with conventional cements types presented the highest bond strength values (p < 0.05).

Intratubular penetration of endodontic sealers depends on the fluorophore used for CLSM assessment.

Root canal filling aims at eliminating empty spaces into the root canal system using biologically compatible materials. Three-dimensional root canal obturation must prevent or minimize the reinfection caused by microorganisms' leakage. This study aimed at evaluating whether fluorophore (Rhodamine or Fluo-3) influences the CLSM images of intratubular penetration of four endodontic sealers. Eighty bovine teeth were prepared using K files up to a size #70 and irrigated with 2.5% sodium hypochlorite. All roots were divided into eight groups (n = 10) according to the sealer and fluorophore used: AH Plus/Rhodamine, AH Plus/Fluo-3, Sealer Plus/Rhodamine, Sealer Plus/Fluo-3, Sealer Plus BC/Rhodamine, Sealer Plus BC/Fluo-3, Endosequence/Rhodamine, and Endosequence/Fluo-3. All roots were filled using cold lateral compaction technique. After 7 days, the roots were transversely sectioned, and three slices, one of each canal third, were obtained. Intratubular penetration was evaluated using CLSM. Sealer Plus BC/Rhodamine and Endosequence BC/Rhodamine presented higher intratubular penetration than AH Plus/Fluo-3 and Sealer Plus/Fluo-3 (p ˂ .05). The intragroup analysis showed similar intratubular penetration, regardless of the root third, except for the apical third in AH Plus/Fluo-3 and Sealer Plus BC/Fluo-3 groups. The type of fluorophore influences the calcium silicate sealers' tubular penetration but not of epoxy resin-based ones using CLSM. Bioceramic sealers should not be used associated with Rhodamine for CLSM evaluation. RESEARCH HIGHLIGHTS: The type of fluorophore influences the calcium silicate sealers' tubular penetration but not of epoxy resin-based ones when CLSM is used for assessment. Bioceramic sealers should not be used associated with Rhodamine.

Interdisciplinary approach using composite resin and ceramic veneers to manage an esthetic challenge.

This clinical report describes the management of an esthetic challenge in an interdisciplinary manner addressing both the soft tissue and the anterior dentition. Different restorative materials were used in an esthetic and conservative manner to provide a pleasing smile. A minimally invasive approach was adopted to manage the anterior esthetics problems, including a maxillary diastema and inadequate width-to-length tooth proportions.

Comparison between isolated and associated with codeine acetaminophen in pain control of acute apical abscess: a randomized clinical trial.

OBJECTIVES: The study aimed to compare the acetaminophen administration efficacy or its combination with codeine for pain control in acute apical abscesses cases. MATERIALS AND METHODS: Thirty-nine patients who sought emergency treatment in the Faculty of Dentistry of the Federal University of Rio Grande do Sul were included, all of them with acute apical abscess diagnosis. These patients were divided into two groups: acetaminophen group-prescription of acetaminophen (1000 mg) and acetaminophen-codeine group-prescription of acetaminophen (1000 mg) + codeine (30 mg), both with oral intake every 6 h for 3 days. The pain scores were recorded by the patients on their own at 6, 12, 24, 48, and 72 h after finishing clinical assistance, by filling a pain evolution journal, containing a visual analogue scale (VAS). Student t test was conducted to investigate different mean ages between groups 1 and 2. A comparison of weight and means of initial pain scores between groups was carried out using the Mann-Whitney U test. Chi-square test was performed to compare gender, affected tooth, education, initial swelling, and frequency of adverse effect between test and control groups. Mann-Whitney U test was applied to compare groups in the same period. Friedman's test was used to compare results from the same group over time. RESULTS: Both groups showed score reduction over time (P < 0.05). Paracetamol-codeine group showed significant pain score reduction at 48 h registers when compared to baseline and at 6 h scores (P < 0.05). Further, pain scores at 72 h were significantly lower, when compared to the baseline, at 6 h, and at 12 h scores (P < 0.05). Acetaminophen group showed significant pain score reduction observed at 72 h, when compared to the baseline and at 6 h scores (P < 0.05). There were no significant differences in pain score reduction over time between groups (P > 0.05). There was no difference between the groups regarding the frequency of adverse reactions (P > 0.05). CONCLUSION: Both medications were effective for pain control in acute apical abscess cases. The findings might have inferred in pain control of acute apical abscess associated pain in patients who used an antibiotic drug. External validity of the findings for acute apical abscess cases with no need for an antibiotic prescription is uncertain. CLINICAL RELEVANCE: This paper suggests acetaminophen 1000 mg can be used for pain control in the treatment of acute apical abscess associated with systemic manifestation.

A New Calcium Silicate-Based Root Canal Dressing: Physical and Chemical Properties, Cytotoxicity and Dentinal Tubule Penetration.

The aims of this study were to evaluate the physical and chemical properties, cytotoxicity and dentinal tubule penetration of a new calcium silicate-based root canal dressing. For pH and calcium ion release evaluation (1, 24, 72 and 168 h) were used a pH meter and colorimetric spectrophotometer, respectively. Radiopacity evaluation followed the ISO 6876:2012. Cytotoxicity was evaluated by the percentage of cell viability using MTT assay. Illustrative images of dentinal tubule penetration were obtained using confocal laser scanning microscopy (CLSM). Data from pH and calcium ion release were statistically analyzed by two-way analysis of variance and Tukey test. Radiopacity was analyzed using the Student t-test. The statistical tests for cytotoxicity results were the one-way analysis of variance and Tukey test. Both materials showed alkaline pH in all experimental times. The pH values for calcium hydroxide paste were higher than bioceramic paste at 1, 24, and 72 h (p<0.05). The calcium ion release of bioceramic was lower than the calcium hydroxide paste only at 24 h (p<0.05). The bioceramic was more radiopaque than the calcium hydroxide paste (p<0.05). Bioceramic paste presented a dose and time-dependent cytotoxic effect after MTT assay. CLSM images showed absence of tubule penetration for both pastes. The new calcium silicate-based canal dressing presented alkaline pH, high calcium release, and acceptable radiopacity. Bio C Temp showed a dose and time-dependent cytotoxic and absence of dentinal tubule penetration.

A new calcium silicate-based root canal dressing: physical and chemical properties, cytotoxicity and dentinal tubule penetration

Abstract The aims of this study were to evaluate the physical and chemical properties, cytotoxicity and dentinal tubule penetration of a new calcium silicate-based root canal dressing. For pH and calcium ion release evaluation (1, 24, 72 and 168 h) were used a pH meter and colorimetric spectrophotometer, respectively. Radiopacity evaluation followed the ISO 6876:2012. Cytotoxicity was evaluated by the percentage of cell viability using MTT assay. Illustrative images of dentinal tubule penetration were obtained using confocal laser scanning microscopy (CLSM). Data from pH and calcium ion release were statistically analyzed by two-way analysis of variance and Tukey test. Radiopacity was analyzed using the Student t-test. The statistical tests for cytotoxicity results were the one-way analysis of variance and Tukey test. Both materials showed alkaline pH in all experimental times. The pH values for calcium hydroxide paste were higher than bioceramic paste at 1, 24, and 72 h (p<0.05). The calcium ion release of bioceramic was lower than the calcium hydroxide paste only at 24 h (p<0.05). The bioceramic was more radiopaque than the calcium hydroxide paste (p<0.05). Bioceramic paste presented a dose and time-dependent cytotoxic effect after MTT assay. CLSM images showed absence of tubule penetration for both pastes. The new calcium silicate-based canal dressing presented alkaline pH, high calcium release, and acceptable radiopacity. Bio C Temp showed a dose and time-dependent cytotoxic and absence of dentinal tubule penetration.

Resumo Os objetivos deste estudo foram avaliar as propriedades físicas e químicas, citototoxidade e penetração tubular de uma nova medicação à base de silicato de cálcio. Para o teste de pH, e liberação de íons cálcio (1, 24, 72 e 168 h) foi usado medidor de pH e espectofotômetro colorimétrico, respectivamente. Avaliação da radiopacidade, seguiu a ISO 6876:2012). A citotoxicidade foi avaliada pela porcentagem de células viáveis usando o ensaio MTT. Imagens ilustrativas de penetração tubular foram obtidas usando microscopia confocal de varredura a laser (CLSM). Os dados de pH e liberação de cálcio foram analisados através do teste de Análise de Variância de duas vias e teste de Tukey. A radiopacidade foi avaliada usando o teste T de Student. Para a citotoxicidade foi empregada a Análise de Variância de uma via e teste de Tukey. Ambos os materiais apresentaram pH alcalino em todos os tempos experimentais. Os valores de pH da pasta de hidróxido de cálcio foram superiores à pasta biocerâmica em 1, 24 e 72 h (p<0,05). A liberação de cálcio da pasta biocerâmica foi inferior à pasta de hidróxido de cálcio apenas em 24 h (p<0,05). Bio-C Temp foi mais radiopaco que o Ultracal XS (p<0,05). A pasta biocerâmica apresentou efeito citotóxico dependente da dose e do tempo de exposição. Imagens de CLSM mostraram ausência de penetração intratubular para ambas as pastas. A nova medicação à base de silicato de cálcio apresentou pH alcalino, alta liberação de cálcio e boa radiopacidade. Bio C Temp apresentou um efeito citotóxico dependente da dose e do tempo de exposição e ausência de penetração tubular.

The influence of titanium base abutments on peri-implant soft tissue inflammatory parameters and marginal bone loss: A randomized clinical trial.

BACKGROUND: Some techniques in implant dentistry have been suggested that may potentially alter peri-implant soft and hard tissue parameters. PURPOSE: To evaluate the peri-implant soft tissue inflammatory parameters and crestal bone loss around titanium base abutments. MATERIALS AND METHODS: Fifty two implants were placed in 21 patients and restored by single crowns. Subjects were randomly allocated into two groups: cement-retained abutment (n = 24) and titanium base (n = 28). Peri-implant probing depth, and mesial and distal marginal bone loss (MBL) were evaluated at implant loading (T1), 6 and 12 months (T2 and T3, respectively). Peri-implant bleeding-on-probing was evaluated at T2 and T3. Two-way repeated measures analysis of variance, Tukey test, Man Whitney, and Pearson correlation were performed for statistical analysis at P < .05. RESULTS: The mean difference of peri-implant MBL from implant installation to 12 months in function was 1.15 ± 0.82 mm for the cement-retained group, and 1.23 ± 0.79 mm for the titanium base group. No statistically significant difference was found between the two groups for clinical and radiographic peri-implant evaluation. CONCLUSIONS: Titanium base abutments present no negative effect on peri-implant soft tissue and MBL. When used to support single crowns, both approaches performed likewise regarding clinical and radiographic parameters.

Beneficial Effects of Ethyl-Cyanoacrylate Coating Against Candida Albicans Biofilm Formation.

The aim of this study was to verify whether modifications made in a hard chairside reline resin by an ethyl-cyanoacrylate adhesive, ECA (Super Bonder®, Loctite, Itapevi, SP, Brazil) would be able to inhibit or reduce Candida albicans biofilm formation on its surface, comparing to a commercial surface sealant (BisCover®, Bisco, Schaumburg, USA). Reline resin specimens were fabricated and randomly divided into 6 groups (n=8): CG (control group), no surface treatment; ECA1, ECA coating on the surface before sterilization; ECA2, ECA coating after sterilization; ECA3, ECA incorporated in the resin bulk; DPE1, BisCover® coating before sterilization; DPE2, BisCover® coating after sterilization. Specimens were inoculated with C. albicans SC5314 (1x107 cells/mL) and incubated for 24 h. Then, the biofilm were stained with LIVE/DEAD® BaclightTM L7007 Kit and analyzed by Confocal Laser Scanning Microscopy. The images were evaluated by bioImageL® v.2.0 software and total biovolume (µm3), viable cells (%), and covered area (%) were calculated. Data were statistically analyzed by Kruskal-Wallis and Dunn tests (p<0.05). Results showed that ECA-coated groups presented better results, reducing C. albicans biofilm formation. Acquired images revealed that these groups (ECA1 and ECA2) presented a reduced number of cells, mostly in yeast form (less pathogenic), while the other groups presented higher number of cells, mostly in hyphae form (more pathogenic). Based on these findings, a beneficial effect of Super Bonder® coating reline resins surface could be demonstrated, suggesting a promising way to prevent fungal biofilm formation on dentures.