RESUMO
The draft genome sequence of Actinobacillus seminis strain ATCC 15768 is reported here. The genome comprises 22 contigs corresponding to 2.36 Mb with 40.7% G+C content and contains several genes related to virulence, including a putative RTX protein.
RESUMO
Rabies virus (RABV), a member of the genus Lyssavirus, causes encephalitis that is almost always fatal following the onset of clinical signs. Here, we report the complete codifying sequence of an RABV isolated from a dog in Mexico. Molecular data showed that this strain belongs to the Chiapas lineage.
RESUMO
Rabies is an infectious viral disease that is practically always fatal following the onset of clinical signs. In Mexico, the last case of human rabies transmitted by dogs was reported in 2006 and canine rabies has declined significantly due to vaccination campaigns implemented in the country. Here we report on the molecular characterization of six rabies virus strains found in Yucatan and Chiapas, remarkably, four of them showed an atypical reaction pattern when antigenic characterization with a reduced panel of eight monoclonal antibodies was performed. Phylogenetic analyses on the RNA sequences unveiled that the three atypical strains from Yucatan are associated with skunks. Analysis using the virus entire genome showed that they belong to a different lineage distinct from the variants described for this animal species in Mexico. The Chiapas atypical strain was grouped in a lineage that was considered extinct, while the others are clustered within classic dog variants.
Assuntos
Doenças do Cão/epidemiologia , Doenças do Cão/virologia , Genótipo , Vírus da Raiva/classificação , Vírus da Raiva/genética , Raiva/veterinária , Animais , Análise por Conglomerados , Transmissão de Doença Infecciosa , Vetores de Doenças , Doenças do Cão/transmissão , Cães , Humanos , Mephitidae/virologia , México/epidemiologia , Epidemiologia Molecular , Filogenia , RNA Viral/genética , Raiva/epidemiologia , Raiva/transmissão , Raiva/virologia , Vírus da Raiva/isolamento & purificação , Análise de Sequência de DNARESUMO
Varicella-zoster virus (VZV) is a member of the Herpesviridae family, which causes varicella (chicken pox) and herpes zoster (shingles) in humans. Here, we report the complete genome sequence of varicella-zoster virus, isolated from a vesicular fluid sample, revealing the circulation of VZV clade VIII in Mexico.
