1.
Carbohydr Res
; 345(12): 1685-97, 2010 Aug 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20584528
RESUMO
The total chemical synthesis of the four well-defined chitodisaccharides is described using N-trichloroacetyl (TCA) and N-benzyloxycarbonyl (Z) as C-2 protecting groups for acetamido and free amino groups, respectively. The synthesis is carried out according to a strategy that paves way to the elaboration of various homo- and hetero-chitooligosaccharides, with perfect control of the number and the position of GlcN and GlcNAc units along the oligomer chain.