RESUMO
The infectivologic risk in hospital environment. After a brief introduction on the historical development of the question of infectivologic risk in health services in general, and, in particular, in hospitals, the principal epidemiologic characteristics of viral hepatitis B and C, of HIV/AIDS and of TBC are examined as well as the potential cancerogenic role of the viral hepatitis. Guide-lines on staff health observation are also presented along with work-fitness criteria.
Assuntos
Síndrome da Imunodeficiência Adquirida/transmissão , Infecções por HIV/transmissão , Hepatite Viral Humana/transmissão , Transmissão de Doença Infecciosa do Paciente para o Profissional , Doenças Profissionais/etiologia , Recursos Humanos em Hospital , Tuberculose/transmissão , Infecções Oportunistas Relacionadas com a AIDS/prevenção & controle , Infecções Oportunistas Relacionadas com a AIDS/transmissão , Síndrome da Imunodeficiência Adquirida/prevenção & controle , Adulto , Serviço Hospitalar de Emergência , Feminino , Infecções por HIV/prevenção & controle , Hepatite B/diagnóstico , Hepatite B/transmissão , Hepatite C/diagnóstico , Hepatite C/transmissão , Hepatite Viral Humana/diagnóstico , Humanos , Masculino , Doenças Profissionais/diagnóstico , Doenças Profissionais/prevenção & controle , Fatores de Risco , Tuberculose/prevenção & controleRESUMO
Data available on biologic fluid content of therapeutic metals are uneven for silver, gold and platinum respectively. Tentative reference values may be proposed on the basis of the most representative studies for silver and gold. For silver it is suggested that the variability in normal subjects could range up to 10 micrograms/l in whole blood and up to 1 microgram/l in urine. For gold 0.5 microgram/l can be considered the upper limit for both whole blood and urine. For platinum there is no indication that concentration in either blood or urine could reach detectable amounts in normal subjects.
Assuntos
Líquidos Corporais/química , Ouro/análise , Platina/análise , Prata/análise , Ouro/sangue , Humanos , Platina/sangue , Valores de Referência , Prata/sangueRESUMO
SEPs obtained by stimulation of the median nerve of the wrist were recorded in a group of 33 subjects working with vibrating instruments in 82% of whom the case history was positive for Raynaud's Phenomenon (RP). Electrophysiological investigation revealed a decrease in peripheral nerve conduction speed, which was related to the duration of exposure to risk and the presence of RP. No diseases of the central nervous system were found. The results are discussed on the basis of the data in the literature.
Assuntos
Potenciais Somatossensoriais Evocados , Nervo Mediano/fisiopatologia , Vibração/efeitos adversos , Adulto , Braço , Humanos , MasculinoAssuntos
Tecido Adiposo/análise , Hidrocarbonetos Clorados , Inseticidas/análise , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Itália , Masculino , Pessoa de Meia-Idade , Caracteres SexuaisRESUMO
Lead intoxication has been reported to occur as a consequence of nonoccupational exposure, the source being mostly the leaching of lead from fluid containers in domestic use. Three such cases are described, for which the cause has been identified to be in the lining of the vat used to contain home-made wine. All cases are members of the same family.
Assuntos
Intoxicação por Chumbo/etiologia , Vinho/intoxicação , Adulto , Cerâmica/normas , Feminino , Fermentação , Manipulação de Alimentos/normas , Utensílios Domésticos/normas , Humanos , Chumbo/análise , Masculino , Vinho/análiseRESUMO
Haemoglobin glycosilate was evaluated using the bio-rad method in 129 diabetics during their periodic visits to outpatient departments. A significant correlation between this test and metabolic compensation was revealed in confirmation of results reported in most research so far carried out. The advantages of using this test in outpatients departments is also emphasised.
Assuntos
Assistência Ambulatorial , Hemoglobinas Glicadas/análise , Adulto , Idoso , Doença Crônica , Diabetes Mellitus/sangue , Diabetes Mellitus/diagnóstico , Diabetes Mellitus/terapia , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
An experimental research was carried out at the Institute of Occupational Health of Turin University on the risks following exposure to oligomers with particular reference to the textile industry. A group of 36 Sprague-Dawley rats were injected endotracheally with a suspension of dust collected from various sections of twisting and spinning departments while 6 rats used a referent groups, were treated with normal solution in the way. Five rats had pneumonia and 1 rat showed the presence of aspecific granuloma whereas the histological patterns for the other rats were found to be similar to those of the control group. In the Authors' opinion it is impossible at the moment, to give a definite conclusion as to the role of oligomers in lung damage.
Assuntos
Poeira/efeitos adversos , Pneumopatias/etiologia , Doenças Profissionais , Indústria Têxtil , Animais , Granuloma/etiologia , Pneumonia/etiologia , Ratos , Ratos Endogâmicos , TêxteisRESUMO
An examination of various commercially available pesticides was made in an evaluation of the potential risks presented by phytopharmaceuticals. It was found that insecticides anticryptogamic products, and weed-killers are most commonly used. Insecticides mainly contain organophosphoric compounds, followed by organochlorates, carbamates, and organic sulphur compounds. Anticryptogamic products are primarily composed of dithiocarbamates, followed by inorganic copper and sulphur compounds. Herbicides are mostly represented by the triazines, followed by phenoxycarboxylic acid derivatives, carbamates, and urea derivatives. Lastly, most pesticides fall into the IIIrd and IVth toxicological classes.
Assuntos
Praguicidas/toxicidade , Carbamatos/toxicidade , Cumarínicos/toxicidade , Herbicidas/toxicidade , Humanos , Inseticidas/toxicidade , Medicina do Trabalho , Compostos Organofosforados/toxicidade , Rodenticidas/toxicidadeRESUMO
Recent advances in the field of occupational toxic haemopathies are described. The nosographical classification of these forms is explained, and an account is given of the main organic and inorganic industrial substances responsible for haematological damage, the sources of risk, the known pathogenetic mechanisms, and the main clinical and morphological aspects of the subject. This question is of a certain current interest, not only from the speculative standpoint, but also with regard to the interesting diagnostic and preventive aspects that are and can be derived from such recent advances.
Assuntos
Doenças Hematológicas/induzido quimicamente , Doenças Profissionais/induzido quimicamente , Derivados de Benzeno/efeitos adversos , Doenças Hematológicas/etiologia , Humanos , Hidrocarbonetos/efeitos adversos , Metais/efeitos adversos , Naftalenos/efeitos adversos , Nitratos/efeitos adversos , Fenóis/efeitos adversosAssuntos
Poeira/análise , Ruído Ocupacional , Ruído , Indústria Têxtil , Animais , Humanos , Microclima , LãRESUMO
Reference is made to the extensive use of pesticides in agriculture and the fact that many are highly toxic. The lack of information and legislative provisions makes agricultural workers particularly vulnerable to the several categories of poisons contained under the description "pesticides". The chlorinated and phosphoric organic compounds are of especial interest. The former include the derivatives of the phenoxycarboxylic acids, which can give rise to a product (tetrachlorobenzodioxine, or dioxine) that was responsible for the pollution at Seveso. The latter group contains the very commonly employed alkylthiophosphates (malathion, parathion, etc.). These are well-known inhibitors of acetylcholine esterase and thus responsible for harm to the nervous system. A comparable, but less intense effect on this esterase is possessed by the carbamates, which are increasingly being used in agriculture. It is hoped that, as in the past, suitable, oriented epidemiological surveys will be carried out in industry, designed to focus attention on the probable, but not yet documented chronic damage that many of these products cause to the human body.
Assuntos
Doenças dos Trabalhadores Agrícolas , Doenças do Sistema Nervoso/induzido quimicamente , Praguicidas/intoxicação , Inibidores da Colinesterase , Humanos , Inseticidas/intoxicação , Itália , Legislação Médica , Malation/intoxicação , Medicina do Trabalho , Paration/intoxicação , Dibenzodioxinas Policloradas/intoxicaçãoRESUMO
The large number of xenobiotic agents, associated with work or otherwise, that can attack the body, and the fundamental part played by the liver in the control of metabolic homeostasis offered the occasion for an examination of the present position with regard to the aetiopathogenesis and diagnosis of occupational toxic diseases of the liver. Attention is particularly directed to recent biochemical knowledge (molecular and cellular), to the main aetiopathogenetic features, and to the most modern criteria for the evaluation of liver damage, especially that of a chronic kind.
Assuntos
Doença Hepática Induzida por Substâncias e Drogas , Fígado/efeitos dos fármacos , Doenças Profissionais , Doença Hepática Induzida por Substâncias e Drogas/diagnóstico , Doença Hepática Induzida por Substâncias e Drogas/etiologia , Humanos , Metais/efeitos adversos , Doenças Profissionais/diagnóstico , Doenças Profissionais/etiologia , Praguicidas/efeitos adversos , Compostos Policíclicos/efeitos adversos , Solventes/efeitos adversosRESUMO
Fasting blood sugar was determined in 277 subjects with early forms of silicosis during statutory outpatient examinations. Values were related to the clinical and occupational history and objective and blood chemistry parameters. The results showed that epidemiological examination is useful in the prevention and early diagnosis of diabetes in occupational environments.