RESUMO
Aplasia cutis congenita (ACC) is a relatively rare congenital anomaly that most commonly occurs as a solitary cutaneous defect on the scalp. Depth of involvement varies, and involvement of deeper calvarium and dural structures can be seen in more severe cases. Multiple classification systems have been devised with the Frieden Classification System being the most widely adopted. Using this system, we describe a patient that developed Type V ACC with associated fetal papyraceous. The child healed remarkably well with the application of petrolatum impregnated gauze and topical silver sulfadiazine twice daily for approximately 4 weeks. The child was noted to have no significant contractures or complications at 6-months and 1-year follow-up exams. Herein, we review the current literature on type V ACC including a discussion of treatment options.
Assuntos
Displasia Ectodérmica/terapia , Anti-Infecciosos Locais/uso terapêutico , Displasia Ectodérmica/etiologia , Humanos , Lactente , Masculino , Prognóstico , Couro Cabeludo , Sulfadiazina de Prata/uso terapêutico , Tronco , CicatrizaçãoRESUMO
Hailey-Hailey disease or familial benign chronic pemphigus is a rare blistering dermatosis that is characterized by recurrent erythematous plaques with a predilection for the skin folds. For extensive Hailey-Hailey disease that is recalcitrant to conventional therapy, laser ablation, photodynamic therapy, electron beam radiotherapy, botulinum toxin type A, dermabrasion, glycopyrrolate, and afamelanotide have been reported as useful treatments, but comparative trials are lacking. This review discusses the various treatment modalities for Hailey-Hailey disease and a summary of the evidence for the most recommended treatments.
Assuntos
Terapia a Laser , Pênfigo Familiar Benigno/terapia , Fotoquimioterapia , Antioxidantes/uso terapêutico , Toxinas Botulínicas Tipo A/uso terapêutico , Ablação por Cateter , Dermabrasão , Glicopirrolato/uso terapêutico , Humanos , Antagonistas Muscarínicos/uso terapêutico , Neurotoxinas/uso terapêutico , Radioterapia , alfa-MSH/análogos & derivados , alfa-MSH/uso terapêuticoRESUMO
Eruptive melanocytic nevi have been reported in association with severe blistering diseases, renal transplantation, malignancy, AIDS, and medications. Eruptive nevi associated with medications have been reported with increasing frequency. Of particular interest are eruptive nevi associated with medications developing in association with biologic therapies, which we anticipate will continue to become more common as use of these medications continues to increase. We searched the databases PubMed/MEDLINE, Cochrane, and Cumulative Index to Nursing and Allied Health Literature for associated medications using the terms "eruptive nevi," "melanocytic + medications," and "nevi + medications" for relevant articles. We report the summary of our findings, which were used in defining what constitutes an eruptive nevi associated with medication and developing a classification system by medication type.
