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Brain Inj ; 34(11): 1541-1547, 2020 09 18.
Artigo em Inglês | MEDLINE | ID: mdl-32816559

RESUMO

Factor XI (FXI) deficiency, also known as hemophilia C, is included in the rare bleeding disorders (RBDs). It is distinct from other coagulation factor deficiencies because it rarely presents as spontaneous hemorrhage, but rather as bleeding after trauma or surgery; in addition, the severity of bleeding does not correlate with FXI levels. Most delayed traumatic intracerebral hemorrhage (DTICH) occurs during the first 72 hours of the trauma. Factors that contribute to its formation include local or systemic coagulopathy, among others. Hemorrhagic cases of FXI deficiency related to the central nervous system (CNS) are very rare, with only 13 reported cases. To the best of our knowledge, this is the first reported case of a DTICH in a patient with undiagnosed FXI deficiency.


Assuntos
Hemorragia Cerebral Traumática , Deficiência do Fator XI , Hemorragia Cerebral Traumática/diagnóstico , Hemorragia Cerebral Traumática/etiologia , Fator XI , Deficiência do Fator XI/complicações , Deficiência do Fator XI/diagnóstico , Hemorragia , Humanos
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