RESUMO
The study aimed to work out the method of cryodestruction of brain tumors. 10 patients with neuroepithelial brain tumors were prospectively operated on with the use of cryodestruction. MRI was performed before and after the operation. The operation strated from tumor biopsy under the ultrasound control with further injection of cryoprobe with further destruction. The study demonstrated that ultrasound navigation is an effective means of the cryodestruction control on all stages. The cryodestruction itself is a miniinvasive, easily controlled and effective method, applicable for tumors, located in functionally important regions of the brain, where major surgery could be mutilating.
Assuntos
Neoplasias Encefálicas/cirurgia , Criocirurgia/métodos , Microcirurgia/métodos , Neoplasias Neuroepiteliomatosas/cirurgia , Procedimentos Neurocirúrgicos/métodos , Neoplasias Encefálicas/diagnóstico , Feminino , Seguimentos , Humanos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Neoplasias Neuroepiteliomatosas/diagnóstico , Estudos ProspectivosRESUMO
26 animals (13 pigs and 13 rabbits) were involved in the study. Liquid nitrogen cryodestruction experimental machine was used. The following measurements and investigation were performed: invasive temperature measurement, intraoperative ultrasound, magnetic resonance imaging and pathomorphologic assessment. An ice sphere was hypoechogenic with hyperechogenic contour by ultrasound. Postoperative MRI showed signs of local ischemic oedema in cryodestruction zone, no signs of bleeding were detected. Morphologically zones of total necrosis, oedema and minor dystrophic changes were recognized. Cryodestruction proved to be a reliable technique of cold brain necrosis.
