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Dig Dis Sci ; 33(9): 1089-95, 1988 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-3044713

RESUMO

Bone biopsies of 52 histologically confirmed alcoholic cirrhotic patients and 15 age- and sex-matched controls have been histomorphometrically analyzed determining trabecular bone volume (TBV), mineralized bone volume (MBV), and osteoid volume (OV). We also determined serum PTH, 25-OH-D3, calcitonin, FSH, LH, estradiol, testosterone, T3 and T4, urine cortisol, routine liver function tests, serum and urinary calcium, phosphorus, and magnesium. We found a high prevalence of osteoporosis: TBV was significantly lower in cirrhotic patients (T = 7.23, P less than 0.001), 41 of them being in the range of osteoporosis; none of them had osteomalacia. Levels of all the above-mentioned hormones and electrolytes were almost normal, and no correlation was found between them and liver function tests, as occurred with the bone parameters.


Assuntos
Osso e Ossos/patologia , Cirrose Hepática Alcoólica/patologia , Adulto , Idoso , Biópsia , Osso e Ossos/metabolismo , Cálcio/sangue , Cálcio/urina , Feminino , Hormônios/sangue , Humanos , Fígado/patologia , Cirrose Hepática Alcoólica/metabolismo , Magnésio/sangue , Magnésio/urina , Masculino , Pessoa de Meia-Idade , Fósforo/sangue , Fósforo/urina
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