Hematuria.

Hematuria is common in the primary care setting. It is classified as either gross or microscopic. Hematuria warrants a thorough history and physical to determine potential causes and assess risk factors for malignancy. Risk of malignancy with gross hematuria is greater than 10%, and prompt urologic referral is recommended. Microscopic hematuria most commonly has benign causes, such as urinary tract infection, benign prostatic hyperplasia, and urinary calculi. If no benign cause for microscopic hematuria is found, the work-up includes laboratory tests to rule out intrinsic renal disease, imaging of the urinary tract, and referral to nephrology and urology subspecialists.

Male group size, female distribution and changes in sexual segregation by Roosevelt elk.

Sexual segregation, or the differential use of space by males and females, is hypothesized to be a function of body size dimorphism. Sexual segregation can also manifest at small (social segregation) and large (habitat segregation) spatial scales for a variety of reasons. Furthermore, the connection between small- and large-scale sexual segregation has rarely been addressed. We studied a population of Roosevelt elk (Cervus elaphus roosevelti) across 21 years in north coastal California, USA, to assess small- and large-scale sexual segregation in winter. We hypothesized that male group size would associate with small-scale segregation and that a change in female distribution would associate with large-scale segregation. Variation in forage biomass might also be coupled to small and large-scale sexual segregation. Our findings were consistent with male group size associating with small-scale segregation and a change in female distribution associating with large-scale segregation. Females appeared to avoid large groups comprised of socially dominant males. Males appeared to occupy a habitat vacated by females because of a wider forage niche, greater tolerance to lethal risks, and, perhaps, to reduce encounters with other elk. Sexual segregation at both spatial scales was a poor predictor of forage biomass. Size dimorphism was coupled to change in sexual segregation at small and large spatial scales. Small scale segregation can seemingly manifest when all forage habitat is occupied by females and large scale segregation might happen when some forage habitat is not occupied by females.

Fetal alcohol spectrum disorders and childhood cancer: a concise review of case reports and future research considerations.

We reviewed the published literature on the relationship between childhood cancer and fetal alcohol spectrum disorders (FASD). A Pub Med search identified 12 subjects with the co-occurrence of FASD and cancer. We included an additional case from the author's institution. Neuroblastomas comprised 6 of the 13 (46%) case reports, yet neuroblastomas comprise only about 10% of childhood cancers (z = 4.1; P < 0.001). Other than rhabdomyosarcoma, no other cancer was reported more than once. Few cases of childhood cancer associated with FASD were identified likely due to under ascertainment of FASD.