RESUMO
We report the case of a 45-year-old woman suffering from anti-hepatitis C virus (HCV) positive chronic active hepatitis and amenorrhea-galactorrhea syndrome due to a prolactin-secreting pituitary microadenoma. She was repeatedly given alpha-interferon for hepatitis, and a concomitant normalization of plasma prolactin levels, with disappearance of the related symptoms, was observed during the treatment. Further experience is needed in order to verify the therapeutical effectiveness of alpha-interferon on prolactin-secreting tumors.
Assuntos
Adenoma/terapia , Antineoplásicos/administração & dosagem , Hepatite C/terapia , Hepatite Crônica/terapia , Interferon-alfa/administração & dosagem , Neoplasias Hipofisárias/terapia , Prolactina/sangue , Prolactina/metabolismo , Adenoma/sangue , Adenoma/metabolismo , Feminino , Hepatite C/sangue , Hepatite Crônica/sangue , Humanos , Interferon alfa-2 , Pessoa de Meia-Idade , Neoplasias Hipofisárias/sangue , Neoplasias Hipofisárias/metabolismo , Prolactina/efeitos dos fármacos , Proteínas Recombinantes , Fatores de TempoRESUMO
At the end of a previous study concerning the use of different buffers for hemodiafiltration (BHDF) in both the re-infusate (40 mM/L) and dialysate (26 mM/L). Retrospective data analysis and showed BHDF to permit good acid/base balance, good clinical tolerability and satisfactory and persistent sense of well-being. From the point of view of kinetics, it is essential to evaluate carefully the acute and/or chronic effect of an alkaline blood pH during or after dial lysis, especially since the volume distribution of bicarbonate is not known.
Assuntos
Bicarbonatos/uso terapêutico , Soluções para Diálise/uso terapêutico , Soluções para Hemodiálise/uso terapêutico , Diálise Renal , Avaliação de Medicamentos , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
The bioelectrical impedance can correctly evaluate the body composition both in normal subjects and those uremia. Thus, due to its reliability and simplicity, it could be largely used not only in normal subjects but also in all the pathologies concerning bodywater and malnutrition.