[Antifungals, their potentials, limits and outlook]. / Antifungicele, posibilitati, limite si perspective.

A review of the history of antifungal therapy shows that after a long period of empiricism the therapeutic arsenal available for the nowadays practitioner has suffered a spectacular change. Indicated in the topical and systemic treatment of mycoses, their practical use requires experience and responsibility. The impartial analysis of their antifungal benefits refers to such targets as: ergosterol, protein syntheses and mitoses from fungal cells.

[Further comment on the importance of microscopy in clinical microbiology. The argument for the diagnosis of the skin manifestations of histoplasmosis and coccidioidomycosis]. / Inca o data despre importanta microscopiei în microbiologia clinica. Argumentum dupa diagnosticarea unor manifestari cutanate ale histoplasmozei si coccidioidomicozei.

This paper presents two interesting cases: a patient with cutaneous coccidioidomycosis, the first case in Romania, and a female patient with latent histoplasmosis with cutaneous manifestations, periodically reactivated during her pregnancies. The etiological diagnosis problems of these affections in relation with the degrees of competence of the clinical laboratories is discussed. The role of direct microscopic examination in the early and more rapid diagnosis of deep mycoses is underlined.

[The etiopathogenesis of psoriasis]. / Beitrag zur Atiopathogenese der Psoriasis.

In the onset, persistence or aggravation of psoriasis numerous factors are involved. This paper is the result of the investigations carried out on 446 cases of psoriasis admitted to the Dermatological Clinic of Iasi and 1455 cases admitted to the Dermatological Clinic of Algeria.

[Esophageal motor disturbances in sclerodermia]. / Tulburari motorii esofagiene in sclerodermie.

By the manometric method the esophageal motility in 14 patients with sclerodermia was studied. All patients presented an esophageal motor dysfunction characterized by the decrease in amplitude of the spohageal contractions, presence of aperistaltic contractions, decrease of basal pressure of the lower esophageal sphincter and its incomplete relaxation at deglutition. These esophageal motor disturbances may appear in association or separately in the same patient. The pathogenesis of the esophageal motor dysfunction in sclerodermia is not yet fully understood. Besides the theoretical interest, the knowledge of the esophageal motor dysfunction in sclerodermia has also a practical value in respect of the tretment which is to be set up.