[Anti-arrhythmia therapy of acute heart rhythm disorders in the early period after heart valve prosthesis]. / Antiaritmicheskaia terapiia ostrykh narushenii serdechnogo ritma v rannie sroki posle protezirovaniia klapanov serdtsa.

The paper reports the results of a comparative study of the efficiency of antiarrhythmic drugs with different mechanisms of action and quickening electric cardiostimulation (ECS) in 640 patients with acute heart rhythm and conductivity disorders that had developed at early dates after the introduction of valvular prostheses. Beta-adrenoblockers and isoptin were shown to be effective in the control of supraventricular tachysystolic rhythm disorders, membrane-stabilizing agents are indicated in ventricular extrasystole, and ECS combined with trimecaine, in bradyarrhythmias. Arterial hypotension associated mostly with obsidan administration, and functional central nervous disturbances observed with membrane-stabilizing agents are reported as the most common side effects. Transformation of arrhythmias into a more severe condition--ventricular tachysystole, fibrillation and asystole--is possible when obsidan or ECS are used.

[Respiratory hypoxia as a heart failure complication in patients with acquired heart defects operated on with artificial circulation and its treatment by artificial pulmonary ventilation with positive expiratory pressure]. / Respiratornaia gipoksiia kak oslozhnenie serdechnoi nedostatochnosti u bol'nykh priobretennymi porokami serdtsa, operirovannykh s iskusstvennym krovoobrashcheniem, i lechenie ee iskusstvennoi ventiliatsiei legkikh s polozhitel'nym davleniem na vydokhe.

The pulmonary gas exchange was studied in 148 patients with prosthesis of the cardiac valves during progressing cardiac insufficiency. It was established that with the increase of cardiac insufficiency respiratory disorders also increase, mainly at the expense of the increase of the intrapulmonary arterio-venous shunting of the blood. The use of artificial lung ventilation with positive expiratory pressure in the post-operative period decreases intrapulmonary shunting, thus increasing the partial pressure and oxygen saturation of the arterial blood, and does not exert depressing action on the cardiac activity.