Evaluation of point-of-care ultrasound use in the diagnostic approach for right upper quadrant abdominal pain management in the emergency department: a prospective study.

Point-of-care ultrasound (PoCUS) is commonly used at the bedside in the emergency department (ED) as part of clinical examinations. Studies frequently investigate PoCUS diagnostic accuracy, although its contribution to the overall diagnostic approach is less often evaluated. The primary objective of this prospective, multicenter, cohort study was to assess the contribution of PoCUS to the overall diagnostic approach of patients with right upper quadrant abdominal pain. Two independent members of an adjudication committee, who were blind to the intervention, independently evaluated the diagnostic approaches before and after PoCUS for the same patient. The study included 62 patients admitted to the ED with non-traumatic right upper quadrant abdominal pain from September 1, 2022, to March 6, 2023. The contribution of PoCUS to the diagnostic approach was evaluated using a proportion test assuming that 75% of diagnostic approaches would be better or comparable with PoCUS. Wilcoxon signed-rank tests evaluated the impact of PoCUS on the mean number of differential diagnoses, planned treatments, and complementary diagnostic tests. Overall, 60 (97%) diagnostic approaches were comparable or better with PoCUS (χ2 = 15.9, p < 0.01). With PoCUS, the mean number of differential diagnoses significantly decreased by 2.3 (95% CI - 2.7 to - 1.5) (p < 0.01), proposed treatments by 1.3 (95% CI - 1.8 to - 0.9) (p < 0.01), and complementary diagnostic tests by 1.3 (95% CI - 1.7 to - 1.0) (p < 0.01). These findings show that PoCUS positively impacts the diagnostic approach and significantly decreases the mean number of differential diagnoses, treatments, and complementary tests.

Correlation between hypoxaemia and lung ultrasound score in patients presenting to an emergency department with interstitial syndrome: a prospective physiological study.

Objective: To assess for the presence of a correlation between lung ultrasound score (LUSS) and ratio between arterial partial pressure of oxygen (PaO2) and the fraction of inspired oxygen (FiO2) in patients presenting to an emergency department (ED) with interstitial syndrome (IS). Design: Prospective, multicentre, physiological study. Setting: Four Belgian hospitals: one tertiary academic centre and three secondary centres. Participants: A convenience sample of adult patients who presented to an ED with acute dyspnoea and needed an arterial blood gas (ABG) analysis (those with a LUSS < 2 were secondarily excluded). Main outcome measure: Correlation between PaO2/FIO2 and LUSS determined using Pearson correlation. Results: In total, 162 adult patients were included. A statistically significant negative linear correlation between PaO2/FIO2 and LUSS was found (correlation coefficient, -0.4860 [95% CI, -0.5956 to -0.3587]; P < 0.0001). Conclusions: Our data provide evidence of a statistically significant negative linear correlation between PaO2/FIO2 and LUSS for ED patients with lung IS. Given the representativeness of PaO2/FIO2 for hypoxaemia and the fact that hypoxaemia indicates IS severity, our findings suggest that LUSS could contribute to the evaluation of IS severity. If confirmed by future studies that include patient follow-up, a noninvasive approach using LUSS could decrease the need for ABG analysis in patients who do not require repeated measurement of ABG values other than PaO2, and thereby improve patient comfort.