RESUMO
Analysis of 84 EEGs recorded during the first 24 hours of life in 80 full-term newborns admitted in intensive care unit for different reasons. - 35 died, 45 survived (normal outcome: 30, minor sequelae: 6, major sequelae: 9). Extremely abnormal EEGs (27 cases) demonstrated singly or in combination: electrical discharges - isoelectric activity (after 10 hours of life) - Permanent discontinuous activity with longest interval greater than 40 seconds, shortest interburst interval greater than 3 seconds, longest burst shorter than 6 seconds. These abnormalities were observed in babies with unfavourable outcome. Normal or minimally abnormal EEGs (31 cases) were observed in babies with normal outcome (21 cases), minor sequelae (3) or in babies died without cerebral injury at autopsy. Twenty-two EEGs could not be classified easily after a single recording, most of then obtained before the 10th hour of life. Sleep state organization was assessed in 56 neonates; sleep state organization was present in 11 infants (normal outcome or minor sequelae). The EEG of the first day of life can be a useful tool in assessing the degree of early cerebral injury in infants requiring intensive care.
Assuntos
Encéfalo/fisiopatologia , Eletroencefalografia , Recém-Nascido , Seguimentos , Humanos , Unidades de Terapia Intensiva Neonatal , Convulsões/fisiopatologia , Sono/fisiologiaAssuntos
Face , Cardiopatias Congênitas/diagnóstico , Deficiência Intelectual/diagnóstico , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , SíndromeRESUMO
The unusual association of Werdnig-Hoffmann disease and nephrogenic diabetes insipidus in a 5-month-old child is described for the first time. The association is casual, considering the different pathways of genetical transmission in these two diseases. The possibility of identifying the heterozygote is discussed and it appears to be limited to nephrogenic diabetes insipidus.
Assuntos
Diabetes Insípido/genética , Paralisia/genética , Diabetes Insípido/complicações , Genes Recessivos , Heterozigoto , Humanos , Lactente , Masculino , Paralisia/complicações , LinhagemRESUMO
The authors have studied the sleep of 6 hydrocephalic infants. In 4 cases disturbed sleep was noticed, characterized by insomnia in 2 cases, and frequent interruptions of sleep in the other 2 cases. In the last cases no other particular alterations were observed. The research was continued in 2 cases, operated on with the Pudenz Valve. In one of which the valve functioned well, sleep was restructured. In the second case the valve did not function well and sleep was not restructured. This suggests the hypothesis that the endocranial hypertension may alter the sleep cycles.
