1.
Bioorg Med Chem Lett
; 14(6): 1509-11, 2004 Mar 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15006392
RESUMO
A new and efficient method for the identification of human cells with positive myeloperoxidase reactivity was developed. This method is based on the myeloperoxidase catalyzed formation of p-naphthoquinone-thiazol-2-on-azine pigments and offers a number of advantages compared to standard methods. In addition, we report the horseradish peroxidase (HRP) catalyzed oxidative coupling of 2-hydrazono-4-thiazolines with alpha-naphthol. This transformation allows a new and efficient synthesis of p-naphthoquinone-thiazol-2-on-azines under mild conditions.