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1.
Can Vet J ; 64(11): 1002-1008, 2023 11.
Artigo em Inglês | MEDLINE | ID: mdl-37915782

RESUMO

Our objective was to report the use of distraction osteogenesis at the site of angular limb deformity correction using external skeletal fixation for treatment of 1 femoral and 1 tibial angular limb deformity in 2 large-breed puppies. Medical records were reviewed from 2 dogs (a 7-month-old intact male golden retriever and a 4-month-old intact female German shepherd mixed breed) diagnosed with angular limb deformities and truncation of a pelvic limb. Surgical treatment consisted of neutral wedge ostectomy and distraction osteogenesis at the site of bone deformity with an external skeletal fixator (ESF). The surgical technique and postoperative period of distraction osteogenesis were reviewed along with postoperative complications and clinical outcomes after complete bone healing was evident radiographically. Both dogs had adequate bone formation during distraction osteogenesis and the ESFs remained intact and structurally stable. At ESF removal, femoral length had increased 2.6 cm for Dog 1 and tibial length increased 3.88 cm for Dog 2, distal femoral valgus improved 16.3 degrees for Dog 1, and tibial procurvatum improved 19.5 degrees and distal tibial valgus improved 6.2 degrees for Dog 2. At the last follow-up examinations, 5 mo (Dog 1) and 3 mo (Dog 2) postoperatively, both dogs were ambulating without any visible lameness. Key clinical message: Acute angular correction and subsequent distraction osteogenesis at the site of bone deformity and corrective ostectomy using an ESF enabled successful treatment of femoral (Dog 1) and tibial (Dog 2) truncation and angulation in 2 large-breed puppies. Optimal deformity correction and lengthening were achieved through distraction osteogenesis at the site of neutral wedge ostectomy, minimizing soft tissue dissection and risk for potential complications that can occur with bifocal deformity correction (i.e., correction of the deformity at 1 osteotomy/ostectomy and correction of bone length at another, remote osteotomy).


Ostéogenèse par distraction au site d'ostectomie en coin neutre pour déformation angulaire du membre postérieur chez 2 jeunes chiens. Notre objectif était de rapporter l'utilisation de l'ostéogenèse par distraction au niveau du site de correction de la déformation angulaire du membre par fixation squelettique externe pour le traitement d'une déformation angulaire fémorale et d'une déformation angulaire tibiale chez 2 chiots de grande race. Les dossiers médicaux ont été examinés concernant 2 chiens (un golden retriever mâle intact âgé de 7 mois et une femelle berger allemand intacte de race mixte âgée de 4 mois) diagnostiqués avec des déformations angulaires des membres et une troncature d'un membre pelvien. Le traitement chirurgical consistait en une ostéogenèse en coin neutre et une ostéogenèse par distraction au niveau du site de déformation osseuse avec un fixateur squelettique externe (FSE). La technique chirurgicale et la période postopératoire d'ostéogenèse par distraction ont été examinées ainsi que les complications postopératoires et les résultats cliniques après une guérison osseuse complète évidente radiographiquement.Les deux chiens présentaient une formation osseuse adéquate pendant l'ostéogenèse par distraction et les FSE restaient intacts et structurellement stables. Lors du retrait de le FSE, la longueur fémorale avait augmenté de 2,6 cm pour le chien 1 et la longueur tibiale de 3,88 cm pour le chien 2, le valgus fémoral distal s'était amélioré de 16,3 degrés pour le chien 1, le procurvatum tibial s'était amélioré de 19,5 degrés et le valgus tibial distal s'était amélioré de 6,2 degrés pour le chien 2. Lors des derniers examens de suivi, 5 mois (chien 1) et 3 mois (chien 2) postopératoires, les deux chiens marchaient sans aucune boiterie visible.Message clinique clé :La correction angulaire aiguë et l'ostéogenèse de distraction ultérieure au site de déformation osseuse et l'ostectomie corrective à l'aide d'un FSE ont permis un traitement réussi de la troncature et de l'angulation fémorale (chien 1) et tibiale (chien 2) chez 2 chiots de grande race. La correction et l'allongement optimaux de la déformation ont été obtenus grâce à l'ostéogenèse par distraction au site de l'ostectomie en coin neutre, minimisant la dissection des tissus mous et le risque de complications potentielles pouvant survenir avec la correction de la déformation bifocale (c'est-à-dire la correction de la déformation à 1 ostéotomie/ostectomie et la correction de la longueur de l'os à une autre ostéotomie distante).(Traduit par Dr Serge Messier).


Assuntos
Osteogênese por Distração , Cães , Masculino , Animais , Feminino , Osteogênese por Distração/veterinária , Osteogênese por Distração/métodos , Desigualdade de Membros Inferiores/cirurgia , Desigualdade de Membros Inferiores/veterinária , Fixadores Externos/veterinária , Extremidade Inferior , Fêmur/cirurgia , Tíbia/cirurgia , Resultado do Tratamento
3.
Anat Rec (Hoboken) ; 301(10): 1697-1713, 2018 10.
Artigo em Inglês | MEDLINE | ID: mdl-29740965

RESUMO

Reconstruction of joint-crossing digital nerves requires the application of nerve guides with a much higher flexibility than used for peripheral nerve repair along larger bones. Nevertheless, collapse-resistance should be preserved to avoid secondary damage to the regrowing nerve tissue. In recent years, we presented chitosan nerve guides (CNGs) to be highly supportive for the regeneration of critical gap length peripheral nerve defects in the rat. Now, we evidently increased the bendability of regular CNGs (regCNGs) by developing a wavy wall structure, that is, corrugated CNGs (corrCNGs). In a comprehensive in vivo study, we compared both types of CNGs with clinical gold standard autologous nerve grafts (ANGs) and muscle-in-vein grafts (MVGs) that have recently been highlighted in the literature as a suitable alternative to ANGs. We reconstructed rat sciatic nerves over a critical gap length of 15 mm either immediately upon transection or after a delay period of 45 days. Electrodiagnostic measurements were applied to monitor functional motor recovery at 60, 90, 120, and 150 (only delayed repair) days postreconstruction. Upon explanation, tube properties were analyzed. Furthermore, distal nerve ends were evaluated using histomorphometry, while connective tissue specimens were subjected to immunohistological stainings. After 120 days (acute repair) or 150 days (delayed repair), respectively, compression-stability of regCNGs was slightly increased while it remained stable in corrCNGs. In both substudies, regCNGs and corrCNGs supported functional recovery of distal plantar muscles in a similar way and to a greater extent when compared with MVGs, while ANGs demonstrated the best support of regeneration. Anat Rec, 301:1697-1713, 2018. © 2018 Wiley Periodicals, Inc.


Assuntos
Regeneração Nervosa , Traumatismos dos Nervos Periféricos/cirurgia , Alicerces Teciduais , Animais , Quitosana , Feminino , Transferência de Nervo , Ratos Endogâmicos Lew , Recuperação de Função Fisiológica , Nervo Isquiático/lesões , Nervo Isquiático/fisiologia , Tempo para o Tratamento , Transplante de Tecidos
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